Motif ID: ZBTB6.p2

Z-value: 1.746


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZBTB6chr9_-_124715392-0.401.2e-01Click!


Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_78829342 3.269 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr12_-_51200347 3.147 NM_000424
KRT5
keratin 5
chr10_-_105604942 2.317 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr7_+_143683365 1.867 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr5_-_149662640 1.650 NM_001012301
ARSI
arylsulfatase family, member I
chr19_+_62703136 1.605 ZNF773
zinc finger protein 773
chr19_+_62703113 1.587 NM_198542
ZNF773
zinc finger protein 773
chr12_-_51132129 1.387 NM_005555
KRT6B
keratin 6B
chr12_-_51173238 1.327 NM_005554
KRT6A
keratin 6A
chr6_+_1257674 1.287 NM_033260
FOXQ1
forkhead box Q1
chr16_-_71650034 1.186 NM_001164766
ZFHX3
zinc finger homeobox 3
chrX_+_17303798 1.172 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr19_+_45915122 1.122 ITPKC
inositol 1,4,5-trisphosphate 3-kinase C
chr1_+_43769065 1.105 NM_002840
NM_130440
PTPRF

protein tyrosine phosphatase, receptor type, F

chr16_-_66007650 1.095 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr3_-_48675321 1.090 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr22_-_45311730 1.077 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_-_235070431 1.024 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr19_-_40693176 1.019 NM_001126059
DMKN
dermokine
chr22_+_22703107 1.015 NM_001144931
LOC391322
D-dopachrome tautomerase-like
chr5_+_79021401 1.014 NM_153610
CMYA5
cardiomyopathy associated 5
chrX_+_17303727 1.013 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr12_-_51153788 1.001 NM_173086
KRT6C
keratin 6C
chrX_-_54538591 0.984 FGD1
FYVE, RhoGEF and PH domain containing 1
chr7_-_143523582 0.962 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr20_+_6696744 0.951 NM_001200
BMP2
bone morphogenetic protein 2
chr3_-_69674412 0.940 FRMD4B
FERM domain containing 4B
chrX_+_17303458 0.939 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_+_21701942 0.937 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr1_-_115014151 0.937 NM_198459
DENND2C
DENN/MADD domain containing 2C
chr22_+_31527744 0.924 TIMP3
TIMP metallopeptidase inhibitor 3
chr22_+_31527678 0.912 TIMP3
TIMP metallopeptidase inhibitor 3
chr14_+_73073570 0.908 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr4_+_30331543 0.899 PCDH7
protocadherin 7
chr2_-_217267742 0.896 IGFBP5
insulin-like growth factor binding protein 5
chr1_-_212791188 0.884 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr19_+_58750305 0.879 NM_001079907
ZNF331
zinc finger protein 331
chr16_-_85099941 0.849 LOC400550
hypothetical LOC400550
chr3_-_191321367 0.846 LEPREL1
leprecan-like 1
chr6_-_10520264 0.817 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_13782838 0.803 NM_006474
NM_198389
PDPN

podoplanin

chr4_+_30330963 0.801 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr3_-_191522886 0.793 NM_021101
CLDN1
claudin 1
chr10_+_47875229 0.793 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr5_-_72779585 0.790 FOXD1
forkhead box D1
chr4_-_119493322 0.787 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr11_-_35503720 0.777 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_212791467 0.765 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr6_+_108988761 0.756 NM_001455
FOXO3
forkhead box O3
chr1_-_203557379 0.754 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr1_-_240754620 0.753 NM_152666
PLD5
phospholipase D family, member 5
chr20_+_19903778 0.750 RIN2
Ras and Rab interactor 2
chr11_-_11986704 0.745 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr8_+_30361485 0.728 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr5_+_52812236 0.728 NM_006350
NM_013409
FST

follistatin

chr7_-_143622188 0.726 ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr10_-_46593923 0.712 NM_001040084
NM_001098845
ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr10_+_47216925 0.712 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr10_-_76829857 0.710 ZNF503
zinc finger protein 503
chr5_-_9599157 0.707 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr17_+_7549138 0.698 NM_001406
EFNB3
ephrin-B3
chr2_-_20288108 0.697 NM_002997
SDC1
syndecan 1
chr11_-_65841077 0.694 NM_020404
CD248
CD248 molecule, endosialin
chr16_+_67698943 0.692 NM_005329
HAS3
hyaluronan synthase 3
chr3_+_10832867 0.691 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr11_+_45825532 0.689 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr16_-_86082818 0.686 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr6_+_1335067 0.684 NM_001452
FOXF2
forkhead box F2
chr1_+_116181927 0.683 NHLH2
nescient helix loop helix 2
chr18_+_40513889 0.682 NM_001130110
SETBP1
SET binding protein 1
chr4_+_30331289 0.678 PCDH7
protocadherin 7
chr11_-_11987115 0.665 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr12_-_28016182 0.662 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr12_-_79855580 0.659 LIN7A
lin-7 homolog A (C. elegans)
chr15_+_43209422 0.650 NM_017434
NM_175940
DUOX1

dual oxidase 1

chr6_+_30958672 0.649 DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_59020875 0.643 JUN
jun proto-oncogene
chr12_+_54612055 0.636 NM_201444
NM_201445
NM_201554
DGKA


diacylglycerol kinase, alpha 80kDa


chr7_-_5429702 0.635 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr9_-_21549696 0.634 LOC554202
hypothetical LOC554202
chr2_+_159533329 0.629 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr14_+_93710401 0.628 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr6_+_43151922 0.628 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr16_-_62573 0.627 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr5_-_72780107 0.624 NM_004472
FOXD1
forkhead box D1
chr16_+_22732982 0.622 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_-_20684858 0.620 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_-_7323528 0.620 ZBTB4
zinc finger and BTB domain containing 4
chr3_+_61522310 0.617 PTPRG
protein tyrosine phosphatase, receptor type, G
chr1_-_231498081 0.617 NM_014801
PCNXL2
pecanex-like 2 (Drosophila)
chr17_+_52026058 0.615 NM_005450
NOG
noggin
chrX_-_51256035 0.610 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr12_-_79855618 0.600 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr5_+_52812165 0.599 FST
follistatin
chr11_-_11987198 0.598 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr3_-_191321601 0.593 NM_018192
LEPREL1
leprecan-like 1
chr10_-_33663984 0.590 NRP1
neuropilin 1
chr12_-_51912101 0.588 NM_000966
RARG
retinoic acid receptor, gamma
chr20_+_13150417 0.584 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr8_+_25098296 0.583 DOCK5
dedicator of cytokinesis 5
chr16_-_11588257 0.577 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr10_-_33663777 0.572 NM_001024628
NM_001024629
NM_003873
NRP1


neuropilin 1


chr8_-_48813256 0.571 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr10_+_75343352 0.567 PLAU
plasminogen activator, urokinase
chr19_+_12966970 0.566 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_-_48813236 0.563 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr19_+_43447262 0.563 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr17_-_7323667 0.562 NM_001128833
ZBTB4
zinc finger and BTB domain containing 4
chr22_+_38720881 0.557 NM_138435
FAM83F
family with sequence similarity 83, member F
chr1_+_182622987 0.556 C1orf21
chromosome 1 open reading frame 21
chr3_-_13896618 0.552 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr1_+_182622850 0.549 C1orf21
chromosome 1 open reading frame 21
chr11_-_114880275 0.548 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr8_-_49996353 0.546 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr16_+_22733307 0.545 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr10_+_101079099 0.544 CNNM1
cyclin M1
chr10_+_123862430 0.541 TACC2
transforming, acidic coiled-coil containing protein 2
chr1_-_6585268 0.540 KLHL21
kelch-like 21 (Drosophila)
chr2_-_19421852 0.539 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr11_-_11987333 0.536 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr17_-_39265965 0.533 NM_001932
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr4_-_177950658 0.531 NM_005429
VEGFC
vascular endothelial growth factor C
chr11_+_45825244 0.530 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr9_-_34448477 0.529 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184944
NM_001184945
NM_147202
C9orf25






chromosome 9 open reading frame 25






chr4_+_152549776 0.526 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr1_+_15957832 0.524 NM_017556
FBLIM1
filamin binding LIM protein 1
chr15_-_38420414 0.522 NM_207380
C15orf52
chromosome 15 open reading frame 52
chr18_-_26876622 0.516 NM_001941
NM_024423
DSC3

desmocollin 3

chr18_-_22382497 0.514 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr17_+_62804036 0.513 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr9_-_103289154 0.512 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr2_+_220017617 0.512 SPEG
SPEG complex locus
chrX_-_131451675 0.511 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr16_+_639278 0.507 NM_145294
WDR90
WD repeat domain 90
chr12_+_26003218 0.506 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr21_-_42789369 0.503 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr19_+_45914755 0.500 NM_025194
ITPKC
inositol 1,4,5-trisphosphate 3-kinase C
chr2_+_36436873 0.499 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_-_65139277 0.493 MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr6_-_10520592 0.491 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr12_-_105165805 0.487 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr10_-_95231933 0.487 NM_013451
NM_133337
MYOF

myoferlin

chr6_-_30820264 0.485 NM_003897
IER3
immediate early response 3
chr1_-_9111674 0.482 NM_024980
GPR157
G protein-coupled receptor 157
chr20_-_4177519 0.481 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr3_-_48445719 0.480 NM_002673
PLXNB1
plexin B1
chr5_-_57791544 0.474 NM_006622
PLK2
polo-like kinase 2
chr19_-_11477395 0.473 ZNF653
zinc finger protein 653
chr1_-_212791597 0.471 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_90957028 0.471 NM_003956
CH25H
cholesterol 25-hydroxylase
chr1_-_215329569 0.470 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr2_-_65512619 0.470 SPRED2
sprouty-related, EVH1 domain containing 2
chr19_-_63138551 0.465 NM_133460
ZNF418
zinc finger protein 418
chr3_-_52065130 0.465 NM_001947
DUSP7
dual specificity phosphatase 7
chr6_+_139055244 0.462 FLJ46906
hypothetical LOC441172
chr10_-_59697636 0.462 NM_152230
IPMK
inositol polyphosphate multikinase
chr17_-_71385651 0.462 TRIM47
tripartite motif containing 47
chr16_+_55217085 0.457 NM_175617
MT1E
metallothionein 1E
chr5_+_49998677 0.455 PARP8
poly (ADP-ribose) polymerase family, member 8
chr10_+_81882477 0.455 PLAC9
placenta-specific 9
chrX_+_73557809 0.454 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr8_+_143778529 0.453 NM_001160354
NM_001160355
NM_017527
LY6K


lymphocyte antigen 6 complex, locus K


chr1_-_223907283 0.451 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr6_+_30018287 0.449 NM_002116
HLA-A
major histocompatibility complex, class I, A
chr6_-_31432543 0.448 HLA-B
major histocompatibility complex, class I, B
chr1_+_107484151 0.444 NM_001113226
NM_001113228
NM_014917
NTNG1


netrin G1


chr5_-_54866126 0.442 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr2_+_238265617 0.439 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr19_+_46390980 0.436 CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr6_-_72187168 0.433 C6orf155
chromosome 6 open reading frame 155
chr3_-_45162783 0.433


chr17_-_76985538 0.432


chr17_+_62803824 0.429 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_+_238265519 0.429 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr12_-_109505409 0.427 NM_139283
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr2_+_220200530 0.426 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr8_-_134653194 0.422 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr11_+_110916629 0.422 LAYN
layilin
chr3_-_75566781 0.417 FAM86DP
family with sequence similarity 86, member D, pseudogene
chr22_+_29808845 0.416 SMTN
smoothelin
chr10_+_81882409 0.415 PLAC9
placenta-specific 9
chr11_+_110916442 0.415 NM_178834
LAYN
layilin
chr7_+_55054416 0.414 EGFR
epidermal growth factor receptor
chr6_+_150505849 0.413 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr10_-_30064600 0.413 NM_003174
SVIL
supervillin
chr4_-_4008063 0.412 LOC348926
family with sequence similarity 86, member A pseudogene
chr12_-_6354650 0.411 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr2_-_72906538 0.409 NM_015189
EXOC6B
exocyst complex component 6B
chr1_-_142535878 0.408 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr10_+_88718167 0.408 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr1_+_9275542 0.403 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr17_+_46067114 0.402 NM_001144070
NM_003786
ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

chr9_-_21999270 0.401 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr16_-_11588525 0.400 LITAF
lipopolysaccharide-induced TNF factor
chrX_-_51256166 0.400 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr17_+_74531873 0.399 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr13_+_92677012 0.399 NM_005708
GPC6
glypican 6
chr8_+_25098171 0.399 NM_024940
DOCK5
dedicator of cytokinesis 5
chr19_+_62690890 0.398 NM_001098491
NM_001098492
NM_001098493
NM_001098494
NM_001098495
NM_001098496
NM_024691
ZNF419






zinc finger protein 419






chr6_+_87921980 0.396 NM_015021
ZNF292
zinc finger protein 292

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 1.28e-10 GO:0009987 cellular process
1.39 5.00e-05 GO:0007399 nervous system development
1.13 1.12e-04 GO:0065007 biological regulation
1.15 1.34e-04 GO:0044238 primary metabolic process
1.49 1.42e-04 GO:0048468 cell development
1.47 1.62e-04 GO:0006793 phosphorus metabolic process
1.47 1.62e-04 GO:0006796 phosphate metabolic process
1.14 2.00e-04 GO:0050794 regulation of cellular process
1.59 2.37e-04 GO:0032989 cellular component morphogenesis
1.23 3.76e-04 GO:0016043 cellular component organization
1.60 3.84e-04 GO:0000902 cell morphogenesis
1.13 4.57e-04 GO:0050789 regulation of biological process
1.32 6.73e-04 GO:0006464 protein modification process
1.27 8.06e-04 GO:0048519 negative regulation of biological process
1.17 8.49e-04 GO:0043170 macromolecule metabolic process
1.21 1.14e-03 GO:0071840 cellular component organization or biogenesis
1.20 1.28e-03 GO:0023052 signaling
1.14 1.39e-03 GO:0044237 cellular metabolic process
1.13 1.53e-03 GO:0008152 metabolic process
1.28 1.78e-03 GO:0048523 negative regulation of cellular process
1.23 2.16e-03 GO:0019538 protein metabolic process
1.62 2.18e-03 GO:0000904 cell morphogenesis involved in differentiation
1.35 2.54e-03 GO:0009966 regulation of signal transduction
1.29 3.62e-03 GO:0043412 macromolecule modification
1.48 4.38e-03 GO:2000026 regulation of multicellular organismal development
1.27 4.81e-03 GO:0048869 cellular developmental process
1.29 6.18e-03 GO:0048583 regulation of response to stimulus
1.75 6.52e-03 GO:0060284 regulation of cell development
1.31 6.92e-03 GO:0023051 regulation of signaling
1.64 7.92e-03 GO:0007409 axonogenesis
1.42 8.89e-03 GO:0022008 neurogenesis
1.57 9.06e-03 GO:0032990 cell part morphogenesis
1.43 1.04e-02 GO:0048699 generation of neurons
1.57 1.08e-02 GO:0048858 cell projection morphogenesis
1.47 1.10e-02 GO:0006468 protein phosphorylation
1.61 1.20e-02 GO:0048812 neuron projection morphogenesis
1.26 1.31e-02 GO:0030154 cell differentiation
1.22 1.45e-02 GO:0048518 positive regulation of biological process
1.19 1.69e-02 GO:0007165 signal transduction
1.72 1.70e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.60 1.93e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.18 1.98e-02 GO:0032502 developmental process
1.40 2.32e-02 GO:0050793 regulation of developmental process
1.48 2.39e-02 GO:0030030 cell projection organization
1.42 2.49e-02 GO:0016310 phosphorylation
1.55 2.49e-02 GO:0031175 neuron projection development
1.18 2.56e-02 GO:0080090 regulation of primary metabolic process
2.14 2.64e-02 GO:0010975 regulation of neuron projection development
1.23 2.70e-02 GO:0048522 positive regulation of cellular process
1.16 2.96e-02 GO:0044260 cellular macromolecule metabolic process
1.40 3.34e-02 GO:0006351 transcription, DNA-dependent
1.19 3.55e-02 GO:0060255 regulation of macromolecule metabolic process
1.46 3.86e-02 GO:0045595 regulation of cell differentiation
1.22 3.94e-02 GO:0071842 cellular component organization at cellular level
1.81 4.78e-02 GO:0048011 nerve growth factor receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.75 8.92e-04 GO:0030426 growth cone
2.67 1.68e-03 GO:0030427 site of polarized growth
1.07 3.97e-03 GO:0005622 intracellular
1.39 1.36e-02 GO:0005624 membrane fraction
1.38 1.36e-02 GO:0005626 insoluble fraction
1.37 1.76e-02 GO:0042995 cell projection
1.82 2.57e-02 GO:0030424 axon
1.43 3.21e-02 GO:0030054 cell junction
1.53 3.66e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 1.62e-06 GO:0005515 protein binding
1.73 2.79e-05 GO:0004674 protein serine/threonine kinase activity
1.08 3.24e-05 GO:0005488 binding
1.50 3.74e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.54 6.86e-04 GO:0004672 protein kinase activity
1.44 2.25e-03 GO:0016301 kinase activity
1.38 2.60e-03 GO:0030528 transcription regulator activity
1.38 4.17e-03 GO:0001071 nucleic acid binding transcription factor activity
1.38 4.17e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 5.90e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.62 1.84e-02 GO:0042578 phosphoric ester hydrolase activity