Motif ID: ZNF143.p2

Z-value: 3.506


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
ZNF143 7702 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF143chr11_+_94390870.001.0e+00Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_48815572 4.206 ZNF428
zinc finger protein 428
chr8_+_145705253 4.125 NM_138431
MFSD3
major facilitator superfamily domain containing 3
chr20_+_55399847 3.300 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr20_-_62058162 2.779 NM_017859
UCKL1
uridine-cytidine kinase 1-like 1
chr16_+_2742320 2.674 NM_016333
SRRM2
serine/arginine repetitive matrix 2
chr1_+_44978145 2.603 KIF2C
kinesin family member 2C
chr1_+_44978120 2.549 KIF2C
kinesin family member 2C
chr16_-_30841938 2.435 NCRNA00095
non-protein coding RNA 95
chr19_+_10261646 2.389 NM_003259
ICAM5
intercellular adhesion molecule 5, telencephalin
chr4_-_1692776 2.309 NM_001127266
NM_138385
TMEM129

transmembrane protein 129

chr22_+_18447732 2.278 NM_001190326
NM_022720
DGCR8

DiGeorge syndrome critical region gene 8

chr6_+_43705254 2.256 NM_001003690
MAD2L1BP
MAD2L1 binding protein
chr16_-_30010705 2.244 NM_004608
TBX6
T-box 6
chr1_+_44978053 2.150 NM_006845
KIF2C
kinesin family member 2C
chr16_-_69030421 2.147 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr15_+_38240501 2.048 NM_001211
BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr4_+_1693031 2.041 NM_006342
TACC3
transforming, acidic coiled-coil containing protein 3
chr17_+_73721924 2.029 BIRC5
baculoviral IAP repeat containing 5
chr3_+_32123004 1.978 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr19_-_47438548 1.975 GSK3A
glycogen synthase kinase 3 alpha
chr15_+_38240555 1.913 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr7_-_150385867 1.911 CDK5
cyclin-dependent kinase 5
chr19_-_47438583 1.900 GSK3A
glycogen synthase kinase 3 alpha
chr7_-_150385912 1.890 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chr1_+_45738442 1.890 NM_015506
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr12_+_52181643 1.858 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr6_-_27548438 1.852 NM_007149
ZNF184
zinc finger protein 184
chr17_+_73721871 1.788 NM_001012270
NM_001012271
NM_001168
BIRC5


baculoviral IAP repeat containing 5


chrX_+_70232362 1.778 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr6_-_43704742 1.760 GTPBP2
GTP binding protein 2
chr19_-_47438518 1.751 GSK3A
glycogen synthase kinase 3 alpha
chr2_-_74610323 1.727 AUP1
ancient ubiquitous protein 1
chr4_-_1692574 1.724 TMEM129
transmembrane protein 129
chr11_-_64334593 1.719 NM_130800
NM_130801
MEN1

multiple endocrine neoplasia I

chr17_-_44847215 1.696 NM_002634
PHB
prohibitin
chr11_+_64565118 1.683 SAC3D1
SAC3 domain containing 1
chr17_+_71292535 1.678


chr2_-_74610331 1.668 AUP1
ancient ubiquitous protein 1
chr8_-_145881968 1.636 ARHGAP39
Rho GTPase activating protein 39
chr17_+_38531134 1.629 NBR2
neighbor of BRCA1 gene 2 (non-protein coding)
chr2_+_74610395 1.619 HTRA2
HtrA serine peptidase 2
chr19_-_48815853 1.609 NM_182498
ZNF428
zinc finger protein 428
chr11_-_64334752 1.605 NM_000244
NM_130799
NM_130802
MEN1


multiple endocrine neoplasia I


chr17_+_71292437 1.600 UNK
unkempt homolog (Drosophila)
chr3_+_32123140 1.596 GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr17_-_44847214 1.594 PHB
prohibitin
chr20_+_41576459 1.589 NM_015478
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr20_-_47238310 1.587 NM_001037328
NM_004602
NM_017452
NM_017453
NM_017454
STAU1




staufen, RNA binding protein, homolog 1 (Drosophila)




chr19_+_61344501 1.580 ZNF444
zinc finger protein 444
chr17_+_71292275 1.566 NM_001080419
UNK
unkempt homolog (Drosophila)
chr1_-_26197121 1.562 NM_000437
PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
chr5_+_85949511 1.540 COX7C
cytochrome c oxidase subunit VIIc
chr2_-_74610332 1.530 AUP1
ancient ubiquitous protein 1
chr8_-_145521324 1.529 DGAT1
diacylglycerol O-acyltransferase 1
chr6_-_43704955 1.516 GTPBP2
GTP binding protein 2
chr22_+_19666616 1.503 LZTR1
leucine-zipper-like transcription regulator 1
chr8_-_145521108 1.502 DGAT1
diacylglycerol O-acyltransferase 1
chr1_-_21982256 1.491 NM_001032730
NM_032236
USP48

ubiquitin specific peptidase 48

chr19_+_3136965 1.484 NCLN
nicalin
chr6_-_43704897 1.484 NM_019096
GTPBP2
GTP binding protein 2
chr22_+_19666575 1.482 LZTR1
leucine-zipper-like transcription regulator 1
chr8_-_145521344 1.479 NM_012079
DGAT1
diacylglycerol O-acyltransferase 1
chr7_-_98901699 1.479 NM_001198879
NM_001190353
NM_001190354
NM_001003713
NM_001003714
NM_001039178
NM_004889
ATP5J2-PTCD1
ATP5J2





ATP5J2-PTCD1 readthrough
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2





chr8_-_145521297 1.457 DGAT1
diacylglycerol O-acyltransferase 1
chr22_+_19666508 1.450 NM_006767
LZTR1
leucine-zipper-like transcription regulator 1
chr2_-_74610346 1.448 AUP1
ancient ubiquitous protein 1
chr5_-_134397740 1.440 NM_002653
PITX1
paired-like homeodomain 1
chr19_-_47438563 1.433 NM_019884
GSK3A
glycogen synthase kinase 3 alpha
chr17_+_77574476 1.430 NM_144999
LRRC45
leucine rich repeat containing 45
chr16_+_2742606 1.423 SRRM2
serine/arginine repetitive matrix 2
chr2_+_74610494 1.414 HTRA2
HtrA serine peptidase 2
chr2_-_74610325 1.388 AUP1
ancient ubiquitous protein 1
chr2_+_38746742 1.371 GALM
galactose mutarotase (aldose 1-epimerase)
chr22_+_24468168 1.346 MYO18B
myosin XVIIIB
chr19_+_61344341 1.326 NM_018337
ZNF444
zinc finger protein 444
chr1_-_218168404 1.326


chr14_+_106009489 1.314 NCRNA00221
non-protein coding RNA 221
chr17_-_38204254 1.310 CCDC56
coiled-coil domain containing 56
chr7_+_149696901 1.309 REPIN1
replication initiator 1
chr2_-_74610481 1.308 NM_181575
AUP1
ancient ubiquitous protein 1
chr17_-_38204208 1.307 NM_001040431
CCDC56
coiled-coil domain containing 56
chr2_-_86186441 1.304 POLR1A
polymerase (RNA) I polypeptide A, 194kDa
chr11_+_64564948 1.303 NM_013299
SAC3D1
SAC3 domain containing 1
chr6_-_4949237 1.298 NM_006638
RPP40
ribonuclease P/MRP 40kDa subunit
chr20_-_62081752 1.298 SAMD10
sterile alpha motif domain containing 10
chr2_+_74610333 1.293 HTRA2
HtrA serine peptidase 2
chr6_+_4948995 1.292 LOC285778
hypothetical protein LOC285778
chr11_+_64564971 1.291 SAC3D1
SAC3 domain containing 1
chr1_-_218168137 1.289 SLC30A10
solute carrier family 30, member 10
chr1_-_1840564 1.276 NM_178545
TMEM52
transmembrane protein 52
chr17_-_35337288 1.273 NM_139280
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr2_-_74610263 1.264 AUP1
ancient ubiquitous protein 1
chr20_-_61809753 1.248 NM_001134758
NM_003224
ARFRP1

ADP-ribosylation factor related protein 1

chr22_+_19078397 1.237 NM_003426
ZNF74
zinc finger protein 74
chr2_+_38746555 1.231 NM_138801
GALM
galactose mutarotase (aldose 1-epimerase)
chr20_-_61809648 1.228 ARFRP1
ADP-ribosylation factor related protein 1
chr20_-_48165886 1.218 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr9_-_116305273 1.210 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr14_-_22468393 1.205 PRMT5
protein arginine methyltransferase 5
chr16_+_2742635 1.191 SRRM2
serine/arginine repetitive matrix 2
chr1_-_10455100 1.189 DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
chr20_-_47238082 1.178 STAU1
staufen, RNA binding protein, homolog 1 (Drosophila)
chr19_+_59310601 1.168 NM_015629
PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr19_+_12778391 1.159 RNASEH2A
ribonuclease H2, subunit A
chr1_-_10455190 1.156 NM_004401
NM_213566
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr16_+_2742641 1.155 SRRM2
serine/arginine repetitive matrix 2
chr16_+_2742653 1.155 SRRM2
serine/arginine repetitive matrix 2
chr10_+_74540215 1.145 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chrX_+_37429927 1.138 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr14_-_23095240 1.131


chr19_-_47438384 1.127 GSK3A
glycogen synthase kinase 3 alpha
chr20_+_61760084 1.126 NM_016434
NM_032957
RTEL1

regulator of telomere elongation helicase 1

chr19_+_4742756 1.125 FEM1A
fem-1 homolog a (C. elegans)
chr11_-_65070625 1.117 LTBP3
latent transforming growth factor beta binding protein 3
chr14_-_22468445 1.116 NM_001039619
NM_006109
PRMT5

protein arginine methyltransferase 5

chr12_+_54784632 1.113 PA2G4
proliferation-associated 2G4, 38kDa
chr16_+_2742657 1.113 SRRM2
serine/arginine repetitive matrix 2
chr2_+_74610635 1.109 HTRA2
HtrA serine peptidase 2
chr8_-_144770764 1.108 TSTA3
tissue specific transplantation antigen P35B
chr8_-_41774296 1.107 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr15_-_62173041 1.106 NM_001014812
NM_032231
FAM96A

family with sequence similarity 96, member A

chr19_-_4131778 1.104 SIRT6
sirtuin 6
chr10_-_69267774 1.104 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr17_-_71352182 1.101 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr19_+_54160468 1.100 FTL
ferritin, light polypeptide
chr16_+_2742674 1.099 SRRM2
serine/arginine repetitive matrix 2
chr12_+_54784614 1.098 PA2G4
proliferation-associated 2G4, 38kDa
chr5_+_85949518 1.097 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr16_+_2742684 1.087 SRRM2
serine/arginine repetitive matrix 2
chr20_+_61809765 1.087 NM_001195653
NM_001195654
NM_032527
NM_181485
ZGPAT



zinc finger, CCCH-type with G patch domain



chr6_-_107542328 1.085 NM_001080450
BEND3
BEN domain containing 3
chr16_+_23597692 1.085 NM_005030
PLK1
polo-like kinase 1
chr16_-_1933190 1.082 SEPX1
selenoprotein X, 1
chr11_-_63690069 1.079 NM_014067
MACROD1
MACRO domain containing 1
chr12_+_54784681 1.077 PA2G4
proliferation-associated 2G4, 38kDa
chr8_-_144770859 1.073 NM_003313
TSTA3
tissue specific transplantation antigen P35B
chr8_-_144770838 1.064 TSTA3
tissue specific transplantation antigen P35B
chr16_+_23597691 1.063 PLK1
polo-like kinase 1
chr8_+_30721208 1.062 NM_005671
UBXN8
UBX domain protein 8
chr16_+_23597735 1.060 PLK1
polo-like kinase 1
chr16_+_2742704 1.054 SRRM2
serine/arginine repetitive matrix 2
chr19_+_3136927 1.053 NCLN
nicalin
chr16_+_2742709 1.046 SRRM2
serine/arginine repetitive matrix 2
chr16_-_1933209 1.045 SEPX1
selenoprotein X, 1
chr12_+_38306238 1.042 NM_001031748
C12orf40
chromosome 12 open reading frame 40
chr19_+_3136860 1.037 NM_020170
NCLN
nicalin
chr13_-_40666392 1.036 KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr14_+_23095028 1.035 NM_001126339
NM_024328
THTPA

thiamine triphosphatase

chr16_+_23597713 1.032 PLK1
polo-like kinase 1
chr12_-_47532171 1.031 NM_004818
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr16_+_2807228 1.029 PRSS21
protease, serine, 21 (testisin)
chr20_+_30259360 1.029 POFUT1
protein O-fucosyltransferase 1
chr19_+_55045754 1.027 PTOV1
prostate tumor overexpressed 1
chr8_+_144870482 1.021 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr7_+_73709943 1.021 NM_001163636
NM_001518
NM_032999
NM_033000
NM_033001
GTF2I




general transcription factor IIi




chr16_-_1933268 1.019 NM_016332
SEPX1
selenoprotein X, 1
chr12_+_54784591 1.014 PA2G4
proliferation-associated 2G4, 38kDa
chr7_+_73709974 1.012 GTF2I
general transcription factor IIi
chr22_+_24468110 1.010 NM_032608
MYO18B
myosin XVIIIB
chr2_+_130703384 1.010


chr16_+_23597661 1.009 PLK1
polo-like kinase 1
chr9_-_139068269 1.003 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr16_+_66433882 0.998 THAP11
THAP domain containing 11
chr12_+_54784625 0.994 PA2G4
proliferation-associated 2G4, 38kDa
chr16_+_2742677 0.985 SRRM2
serine/arginine repetitive matrix 2
chr5_-_134397470 0.980 PITX1
paired-like homeodomain 1
chr17_+_38204335 0.978 NM_173478
CNTD1
cyclin N-terminal domain containing 1
chr20_+_30259359 0.977 POFUT1
protein O-fucosyltransferase 1
chr17_+_69939806 0.969 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr7_+_73709991 0.967 GTF2I
general transcription factor IIi
chr6_+_53037754 0.964 NM_033481
FBXO9
F-box protein 9
chr2_+_218896102 0.958 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr17_-_36938111 0.958 NM_002276
KRT19
keratin 19
chr13_-_40666533 0.957 NM_032138
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr22_+_21852699 0.956 BCR
breakpoint cluster region
chr20_+_30259235 0.952 NM_015352
NM_172236
POFUT1

protein O-fucosyltransferase 1

chr15_+_38843535 0.946 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr17_-_36938025 0.942 KRT19
keratin 19
chr1_+_246087230 0.939 TRIM58
tripartite motif containing 58
chr10_-_13430195 0.935 NM_001195602
NM_001195604
NM_012247
SEPHS1


selenophosphate synthetase 1


chr3_-_15081705 0.934 MRPS25
mitochondrial ribosomal protein S25
chr1_-_54076521 0.929 TMEM48
transmembrane protein 48
chr2_+_74610624 0.928 HTRA2
HtrA serine peptidase 2
chr14_-_23090606 0.927 NM_033400
ZFHX2
zinc finger homeobox 2
chr2_+_74610039 0.920 NM_013247
NM_145074
HTRA2

HtrA serine peptidase 2

chr16_-_4605003 0.917 FAM100A
family with sequence similarity 100, member A
chr3_+_140148765 0.910 NM_001040061
C3orf72
chromosome 3 open reading frame 72
chr17_-_3814334 0.908 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr8_-_145612636 0.905 NM_017767
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_-_1441403 0.905 NM_017573
PCSK4
proprotein convertase subtilisin/kexin type 4
chr20_+_337346 0.904 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr2_+_218896219 0.904 PNKD
paroxysmal nonkinesigenic dyskinesia
chr12_+_54784600 0.899 PA2G4
proliferation-associated 2G4, 38kDa
chr17_+_37694007 0.895 STAT5A
signal transducer and activator of transcription 5A
chr19_-_41955493 0.892 NM_001193552
ZNF850
zinc finger protein 850
chr19_+_55627971 0.885 NM_004533
MYBPC2
myosin binding protein C, fast type
chr12_+_56168120 0.885 MARS
methionyl-tRNA synthetase
chr19_+_4742727 0.884 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr8_+_67742348 0.882 C8orf44
chromosome 8 open reading frame 44
chr9_-_125732005 0.880 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 7.02e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 9.73e-07 GO:0044260 cellular macromolecule metabolic process
1.39 1.92e-06 GO:0090304 nucleic acid metabolic process
1.31 4.26e-06 GO:0034641 cellular nitrogen compound metabolic process
1.30 5.69e-06 GO:0006807 nitrogen compound metabolic process
1.19 6.21e-06 GO:0044237 cellular metabolic process
1.39 5.89e-05 GO:0010467 gene expression
1.17 2.25e-04 GO:0044238 primary metabolic process
1.15 3.32e-04 GO:0008152 metabolic process
1.20 3.37e-04 GO:0043170 macromolecule metabolic process
1.39 3.39e-04 GO:0016070 RNA metabolic process
1.66 1.42e-03 GO:0000278 mitotic cell cycle
2.08 2.40e-03 GO:0071156 regulation of cell cycle arrest
2.07 4.69e-03 GO:0000075 cell cycle checkpoint
2.08 6.91e-03 GO:0006457 protein folding
1.58 8.93e-03 GO:0006396 RNA processing
1.86 1.05e-02 GO:0051329 interphase of mitotic cell cycle
1.82 1.82e-02 GO:0051325 interphase
1.77 1.90e-02 GO:0010564 regulation of cell cycle process
1.52 3.87e-02 GO:0022403 cell cycle phase
1.32 4.25e-02 GO:0034645 cellular macromolecule biosynthetic process
1.25 4.26e-02 GO:0044267 cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 6.20e-23 GO:0044424 intracellular part
1.16 4.15e-22 GO:0005622 intracellular
1.22 1.10e-19 GO:0043227 membrane-bounded organelle
1.20 1.93e-19 GO:0043226 organelle
1.22 2.98e-19 GO:0043231 intracellular membrane-bounded organelle
1.20 6.12e-19 GO:0043229 intracellular organelle
1.24 3.46e-11 GO:0044444 cytoplasmic part
1.25 1.22e-10 GO:0005634 nucleus
1.18 3.40e-10 GO:0005737 cytoplasm
1.24 6.35e-10 GO:0044422 organelle part
1.24 1.11e-09 GO:0044446 intracellular organelle part
1.39 5.48e-08 GO:0031974 membrane-enclosed lumen
1.40 6.81e-08 GO:0070013 intracellular organelle lumen
1.38 1.80e-07 GO:0043233 organelle lumen
1.39 3.39e-07 GO:0044428 nuclear part
1.28 7.42e-07 GO:0032991 macromolecular complex
1.78 1.15e-05 GO:0030529 ribonucleoprotein complex
1.37 3.51e-05 GO:0031981 nuclear lumen
1.64 3.84e-05 GO:0015630 microtubule cytoskeleton
1.31 4.66e-04 GO:0005829 cytosol
1.26 5.80e-04 GO:0043228 non-membrane-bounded organelle
1.26 5.80e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.39 9.15e-04 GO:0005654 nucleoplasm
1.35 5.61e-03 GO:0005739 mitochondrion
1.75 5.61e-03 GO:0005815 microtubule organizing center
1.22 7.27e-03 GO:0043234 protein complex
1.95 2.17e-02 GO:0005840 ribosome
1.44 4.09e-02 GO:0031967 organelle envelope

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.24 4.08e-04 GO:0003676 nucleic acid binding
1.51 1.09e-03 GO:0003723 RNA binding
1.07 5.93e-03 GO:0005488 binding
2.16 9.14e-03 GO:0003735 structural constituent of ribosome
1.12 1.41e-02 GO:0005515 protein binding
2.28 1.69e-02 GO:0051082 unfolded protein binding
1.27 3.48e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.30 3.68e-02 GO:0005524 ATP binding
1.26 3.93e-02 GO:0008270 zinc ion binding
1.30 4.60e-02 GO:0032559 adenyl ribonucleotide binding