Motif ID: NR6A1.p2

Z-value: 0.371


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR6A1chr9_-_1265733490.282.9e-01Click!


Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_129245978 0.543 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr19_-_6671585 0.455 NM_000064
C3
complement component 3
chr6_+_84799969 0.445 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr11_+_111294868 0.436 C11orf52
chromosome 11 open reading frame 52
chr10_-_126097444 0.426 OAT
ornithine aminotransferase
chr1_+_144152864 0.416 TXNIP
thioredoxin interacting protein
chr10_-_126097483 0.408 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr9_-_38059207 0.390 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr1_-_156923111 0.380 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_+_146906520 0.360 NM_006834
RAB32
RAB32, member RAS oncogene family
chr9_+_123083540 0.332 GSN
gelsolin
chr3_-_127719283 0.317 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chrX_+_48505097 0.311 NM_001080489
GLOD5
glyoxalase domain containing 5
chr9_-_14303509 0.306 NFIB
nuclear factor I/B
chr7_+_73506172 0.282 GTF2IRD1
GTF2I repeat domain containing 1
chr6_+_32114060 0.262 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr20_-_42457717 0.259


chr7_-_149669622 0.259 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr3_+_186529376 0.257 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_+_111294810 0.234 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr9_-_14303899 0.234 NFIB
nuclear factor I/B
chr8_-_145672525 0.232 NM_003923
FOXH1
forkhead box H1
chr3_-_140879463 0.223 NM_178177
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr9_-_38059082 0.213 SHB
Src homology 2 domain containing adaptor protein B
chr7_+_37926943 0.204 EPDR1
ependymin related protein 1 (zebrafish)
chr7_+_73506047 0.196 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr10_+_123744131 0.191 TACC2
transforming, acidic coiled-coil containing protein 2
chrX_-_21686079 0.191 NM_014332
SMPX
small muscle protein, X-linked
chr2_-_128792515 0.189 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr8_-_37576515 0.184 LOC157860
hypothetical protein LOC157860
chr9_-_14303943 0.181 NFIB
nuclear factor I/B
chr1_-_205290921 0.177 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr12_+_107797985 0.174 NM_001917
DAO
D-amino-acid oxidase
chr16_-_68317945 0.173 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr10_+_106003941 0.171 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr17_-_40339919 0.168 GFAP
glial fibrillary acidic protein
chr17_-_45280377 0.168 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr1_-_6684426 0.153 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr16_+_82540172 0.148 NM_013370
NM_182980
OSGIN1

oxidative stress induced growth inhibitor 1

chr9_-_14304036 0.147 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr16_+_24765052 0.139 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr6_-_133076873 0.137 NM_004666
VNN1
vanin 1
chr12_+_52696908 0.131 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr2_-_162638746 0.130 DPP4
dipeptidyl-peptidase 4
chr17_-_45619038 0.126 COL1A1
collagen, type I, alpha 1
chr6_+_43136159 0.124 NM_201522
KLC4
kinesin light chain 4
chr3_+_46594079 0.123 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr6_-_132952517 0.123 NM_003967
TAAR5
trace amine associated receptor 5
chr7_+_1543644 0.121 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_117253882 0.119 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr7_+_100037817 0.118 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr20_-_29464301 0.116 NM_001171832
DEFB121
defensin, beta 121
chr2_-_162638875 0.112 DPP4
dipeptidyl-peptidase 4
chr17_+_71586857 0.110 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr1_-_925332 0.110 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr16_-_65781499 0.101 NM_178516
EXOC3L1
exocyst complex component 3-like 1
chr12_+_7039453 0.094


chr12_+_52697160 0.092 HOXC5
HOXC6
homeobox C5
homeobox C6
chr11_-_16387001 0.090 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr6_-_2696152 0.089 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr1_+_196153122 0.089 NM_020204
LHX9
LIM homeobox 9
chr3_-_150286812 0.088 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr4_+_41309482 0.085 LIMCH1
LIM and calponin homology domains 1
chr3_+_134947894 0.084 TF
transferrin
chr1_-_159435440 0.083 NM_005099
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr22_+_19649460 0.081 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr21_+_32687282 0.080 C21orf119
chromosome 21 open reading frame 119
chr2_-_210798232 0.079 NM_001608
ACADL
acyl-CoA dehydrogenase, long chain
chr11_-_64520964 0.075 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr15_+_87540238 0.070 ABHD2
abhydrolase domain containing 2
chr1_+_40769877 0.069 ZNF684
zinc finger protein 684
chr2_-_162638790 0.069 DPP4
dipeptidyl-peptidase 4
chr16_+_55199978 0.064 NM_005953
MT2A
metallothionein 2A
chr16_-_57309625 0.064 GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chr6_-_43592670 0.063 YIPF3
Yip1 domain family, member 3
chr7_+_28497272 0.060 CREB5
cAMP responsive element binding protein 5
chr3_+_134947573 0.060 NM_001063
TF
transferrin
chr3_+_134947788 0.058 TF
transferrin
chr21_+_41610530 0.055 NM_058186
NM_206964
FAM3B

family with sequence similarity 3, member B

chrX_+_54483565 0.052 NM_058163
TSR2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr11_-_2113297 0.051 IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_73397929 0.050 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr21_+_44902276 0.049 NM_198697
KRTAP12-3
keratin associated protein 12-3
chr8_-_125648576 0.048 MTSS1
metastasis suppressor 1
chr2_+_26422495 0.047 EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr12_-_6354650 0.047 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr2_-_162638174 0.046 DPP4
dipeptidyl-peptidase 4
chr8_-_145671947 0.044 FOXH1
forkhead box H1
chr15_+_61122957 0.044 TPM1
tropomyosin 1 (alpha)
chr11_+_111462743 0.043 NM_003002
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr7_-_126670804 0.043 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr22_+_19649417 0.042 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr17_-_24426752 0.041 NM_004740
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr16_-_3246587 0.040 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr1_-_10964680 0.040 NM_001170754
C1orf127
chromosome 1 open reading frame 127
chr17_+_75507750 0.039


chr1_-_16006779 0.039 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr5_-_65053630 0.037 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr19_+_46390916 0.033 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr4_-_160175782 0.033 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr17_+_77289704 0.032 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_+_30964441 0.032 NM_013994
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_-_224611568 0.031 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_-_105228986 0.031 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr1_+_45046740 0.029 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr6_-_116706828 0.029 TSPYL1
TSPY-like 1
chr22_+_21393107 0.029 IGLJ3
immunoglobulin lambda joining 3
chr8_+_142501188 0.029 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr11_+_111462821 0.028 SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr17_+_44325127 0.027 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr1_-_222100006 0.027 TP53BP2
tumor protein p53 binding protein, 2
chr12_-_10453409 0.027 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chrX_+_8392870 0.025 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr1_-_46541517 0.025 LRRC41
leucine rich repeat containing 41
chr12_-_108736983 0.024 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr1_+_40769819 0.024 NM_152373
ZNF684
zinc finger protein 684
chr19_-_5797465 0.024 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr1_+_224064365 0.024 NM_001136018
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr4_+_1923629 0.023 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chrX_+_17563333 0.023 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr19_+_8814268 0.023 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr2_+_26422404 0.023 NM_033505
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr5_-_41249270 0.022 NM_000065
C6
complement component 6
chr2_+_96672200 0.021 NM_001113382
FER1L5
fer-1-like 5 (C. elegans)
chr3_+_39826032 0.021 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr22_+_21559959 0.021 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr16_-_70591377 0.019 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr11_-_55815113 0.019 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr7_+_55999559 0.019 NM_001483
GBAS
glioblastoma amplified sequence
chr7_-_97439500 0.019 MGC72080
MGC72080 pseudogene
chr1_+_151873134 0.019 NM_015607
C1orf77
chromosome 1 open reading frame 77
chr1_+_217413746 0.018 NM_138794
LYPLAL1
lysophospholipase-like 1
chr9_+_37475911 0.018 NM_022490
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr12_+_103675075 0.018 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr5_+_175241449 0.018 CPLX2
complexin 2
chr1_+_150005754 0.017 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr6_-_43592679 0.017 NM_015388
YIPF3
Yip1 domain family, member 3
chr17_-_57023322 0.017 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr2_-_21084911 0.017 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_117910472 0.016 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr2_+_190710730 0.016 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr1_+_217413818 0.016 LYPLAL1
lysophospholipase-like 1
chr1_+_210805319 0.016 NM_001030287
ATF3
activating transcription factor 3
chr8_-_53789544 0.016 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr13_+_22653059 0.015 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr2_-_97775300 0.015 TMEM131
transmembrane protein 131
chr7_-_65084597 0.014 GUSB
glucuronidase, beta
chr1_+_46151845 0.014 MAST2
microtubule associated serine/threonine kinase 2
chr6_+_142510034 0.014 VTA1
Vps20-associated 1 homolog (S. cerevisiae)
chr3_-_38153467 0.014 ACAA1
acetyl-CoA acyltransferase 1
chr7_+_5904858 0.014 NM_015622
C7orf28B
CCZ1
chromosome 7 open reading frame 28B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr6_-_43592481 0.013 YIPF3
Yip1 domain family, member 3
chr1_+_75962630 0.013 NM_000016
NM_001127328
ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain

chr1_+_224064427 0.013 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr1_-_151873191 0.013 NM_001024210
S100A13
S100 calcium binding protein A13
chr7_-_65084622 0.012 GUSB
glucuronidase, beta
chr10_+_124020810 0.012 NM_144587
BTBD16
BTB (POZ) domain containing 16
chr19_-_2668272 0.011 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr13_+_23723831 0.011 SPATA13
spermatogenesis associated 13
chr12_-_16652202 0.011 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_208763017 0.010 NM_001099334
C2orf80
chromosome 2 open reading frame 80
chrX_+_48803459 0.010 NM_001163322
NM_033626
NM_001163321
NM_001163323
CCDC120



coiled-coil domain containing 120



chr11_-_111462627 0.009 NM_012459
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr7_-_65084641 0.009 GUSB
glucuronidase, beta
chr19_-_54231884 0.008 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr2_-_31214868 0.008


chr12_-_61832856 0.008 NM_000706
AVPR1A
arginine vasopressin receptor 1A
chr14_-_105712630 0.008 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_+_74326536 0.007 NM_138691
TMC1
transmembrane channel-like 1
chr22_+_49388427 0.007 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr1_+_26376560 0.007 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr1_+_143920424 0.007 NM_203458
NOTCH2NL
notch 2 N-terminal like
chr1_-_29380945 0.006 SRSF4
serine/arginine-rich splicing factor 4
chr1_-_20707196 0.006 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr11_+_35640918 0.006 NM_017583
TRIM44
tripartite motif containing 44
chr4_-_47709717 0.006 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_-_209732881 0.006 NM_001164688
NM_183059
RD3

retinal degeneration 3

chr16_+_3391155 0.006 NM_001032292
NM_003450
ZNF174

zinc finger protein 174

chr12_+_2792047 0.005 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr18_-_648246 0.005 NM_001012716
C18orf56
chromosome 18 open reading frame 56
chr8_-_27906287 0.005 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr9_+_139101235 0.005 NM_016219
MAN1B1
mannosidase, alpha, class 1B, member 1
chr4_+_41309690 0.005 LIMCH1
LIM and calponin homology domains 1
chr6_-_150001376 0.005 NM_007044
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr4_-_154900466 0.004


chr1_-_120413698 0.004 NOTCH2
notch 2
chr11_-_7917642 0.004 NM_001003745
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr9_-_28709302 0.004 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr6_+_167504070 0.003 NM_001145121
TCP10L2
TCP10
t-complex 10-like 2 (mouse)
t-complex 10 homolog (mouse)
chr6_-_31007905 0.003 NM_205854
SFTA2
surfactant associated 2
chr2_+_102744921 0.003 NM_144632
TMEM182
transmembrane protein 182
chr12_+_119632213 0.003 NM_001080533
UNC119B
unc-119 homolog B (C. elegans)
chr3_+_114948600 0.003 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr1_+_62835759 0.002 NM_014495
ANGPTL3
angiopoietin-like 3
chr12_+_54045161 0.002 NM_001005497
OR6C75
olfactory receptor, family 6, subfamily C, member 75
chr1_+_26376611 0.002 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr9_+_35782405 0.002 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr12_-_46439127 0.002 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr10_+_51507891 0.002 NM_018232
FAM21B
family with sequence similarity 21, member B
chr6_-_25982418 0.001 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.