Motif ID: LHX3,4.p2

Z-value: 0.779


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LHX3chr9_-_138234707-0.234.0e-01Click!
LHX4chr1_+_1784660640.117.0e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_88155360 2.771 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr19_-_56612653 2.023 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
 SIGLEC10






sialic acid binding Ig-like lectin 10






chr2_-_175170674 1.451 WIPF1
WAS/WASL interacting protein family, member 1
chr17_+_19917420 1.290 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr13_+_23042722 1.234 NM_148957
 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr16_+_11966464 1.197 NM_001192
 TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr18_+_59767567 1.148 NM_001123366
 HMSD
histocompatibility (minor) serpin domain containing
chr1_+_196874839 1.126 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_-_32265489 1.093 NM_002586
 PBX2
pre-B-cell leukemia homeobox 2
chr12_-_101396459 1.036 NM_001111284
 IGF1
insulin-like growth factor 1 (somatomedin C)
chr1_-_114215768 0.970 NM_001193431
NM_012411
NM_015967
 PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr3_-_57209319 0.965 NM_003865
 HESX1
HESX homeobox 1
chr19_+_14554895 0.948 NM_207390
 CLEC17A
C-type lectin domain family 17, member A
chr1_-_92725017 0.876 NM_005263
 GFI1
growth factor independent 1 transcription repressor
chr20_-_51633042 0.870 NM_006526
 ZNF217
zinc finger protein 217
chr7_-_25234582 0.870 NM_022150
 NPVF
neuropeptide VF precursor
chr7_+_90177082 0.829 CDK14
cyclin-dependent kinase 14
chr5_+_67622242 0.821 NM_181504
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr17_-_38087366 0.796 NM_016602
 CCR10
chemokine (C-C motif) receptor 10
chr22_+_38627129 0.782 GRAP2
GRB2-related adaptor protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.48 7.31e-06 GO:0007608 sensory perception of smell
2.22 2.60e-04 GO:0007606 sensory perception of chemical stimulus
1.55 1.16e-03 GO:0003008 system process
1.55 1.68e-02 GO:0050877 neurological system process
1.25 7.61e-03 GO:0032501 multicellular organismal process
1.24 7.33e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.34 1.58e-05 GO:0071944 cell periphery
1.33 2.30e-05 GO:0005886 plasma membrane
1.21 8.08e-03 GO:0016021 integral to membrane
1.20 2.18e-02 GO:0031224 intrinsic to membrane
1.17 4.37e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
6.34 9.46e-03 GO:0001608 nucleotide receptor activity, G-protein coupled
6.34 9.46e-03 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
2.60 3.57e-07 GO:0004984 olfactory receptor activity
2.16 3.62e-09 GO:0004930 G-protein coupled receptor activity
1.79 6.27e-07 GO:0004888 transmembrane receptor activity
1.70 1.41e-07 GO:0004872 receptor activity
1.55 5.99e-06 GO:0004871 signal transducer activity
1.55 5.99e-06 GO:0060089 molecular transducer activity