Motif ID: MYFfamily.p2

Z-value: 2.072


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYF6chr12_+_796255380.292.7e-01Click!
MYF5chr12_+_796348200.282.9e-01Click!
MYOD1chr11_+_176976850.263.2e-01Click!
MYOGchr1_-_2013219990.097.3e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_74710741 6.762 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr6_+_45498354 4.417 RUNX2
runt-related transcription factor 2
chr6_+_45498262 3.518 RUNX2
runt-related transcription factor 2
chr5_-_178705036 3.264 NM_014244
NM_021599
 ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr6_+_107917965 3.242 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chr4_+_3046034 3.183 NM_002111
 HTT
huntingtin
chr1_-_72521079 3.021


chr1_-_56817802 2.831 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_88269884 2.758 DUSP6
dual specificity phosphatase 6
chr18_+_59788242 2.716 NM_001031848
NM_002640
NM_198833
 SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr9_-_83494198 2.708 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr5_-_178704934 2.594 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr2_-_161058120 2.572 RBMS1
RNA binding motif, single stranded interacting protein 1
chr3_-_31997738 2.572 OSBPL10
oxysterol binding protein-like 10
chr12_+_64504835 2.376 HMGA2
high mobility group AT-hook 2
chr12_-_74711474 2.323 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr6_+_129245978 2.304 NM_000426
NM_001079823
 LAMA2

laminin, alpha 2

chr18_-_24010944 2.277 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_-_72520735 2.275 NM_173808
 NEGR1
neuronal growth regulator 1
chr12_-_88270128 2.270 DUSP6
dual specificity phosphatase 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 81 entries
enrichment   p-value GO term description
2.23 2.30e-04 GO:0048736 appendage development
2.23 2.30e-04 GO:0060173 limb development
2.23 1.74e-02 GO:0002576 platelet degranulation
2.22 8.91e-03 GO:0007160 cell-matrix adhesion
2.21 3.85e-03 GO:0030326 embryonic limb morphogenesis
2.21 3.85e-03 GO:0035113 embryonic appendage morphogenesis
2.16 1.90e-03 GO:0035107 appendage morphogenesis
2.16 1.90e-03 GO:0035108 limb morphogenesis
2.05 3.08e-02 GO:0031589 cell-substrate adhesion
1.75 2.15e-03 GO:0030168 platelet activation
1.73 5.94e-04 GO:0061061 muscle structure development
1.71 1.86e-02 GO:0048514 blood vessel morphogenesis
1.69 3.97e-03 GO:0001568 blood vessel development
1.67 8.34e-03 GO:2000145 regulation of cell motility
1.67 1.02e-02 GO:0030334 regulation of cell migration
1.65 8.96e-04 GO:0007411 axon guidance
1.65 5.85e-03 GO:0001944 vasculature development
1.65 5.85e-03 GO:0040012 regulation of locomotion
1.62 1.35e-02 GO:0051270 regulation of cellular component movement
1.59 4.06e-05 GO:0000904 cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
4.46 5.00e-03 GO:0005583 fibrillar collagen
3.03 3.48e-04 GO:0005581 collagen
2.55 4.19e-03 GO:0031093 platelet alpha granule lumen
2.52 2.22e-03 GO:0031983 vesicle lumen
2.50 6.40e-03 GO:0034774 secretory granule lumen
2.40 1.42e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.26 2.13e-02 GO:0031091 platelet alpha granule
2.03 1.01e-03 GO:0044420 extracellular matrix part
1.81 2.01e-07 GO:0005578 proteinaceous extracellular matrix
1.80 7.64e-09 GO:0031012 extracellular matrix
1.79 2.23e-02 GO:0043235 receptor complex
1.55 7.44e-04 GO:0009986 cell surface
1.48 1.21e-09 GO:0044421 extracellular region part
1.41 9.21e-05 GO:0005615 extracellular space
1.37 1.52e-02 GO:0030054 cell junction
1.36 8.42e-12 GO:0005576 extracellular region
1.27 2.64e-03 GO:0031226 intrinsic to plasma membrane
1.27 6.08e-03 GO:0005887 integral to plasma membrane
1.25 1.10e-05 GO:0044459 plasma membrane part
1.15 3.49e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.80 1.11e-04 GO:0005520 insulin-like growth factor binding
2.92 3.04e-02 GO:0005158 insulin receptor binding
2.40 9.37e-07 GO:0019838 growth factor binding
2.18 5.24e-03 GO:0005201 extracellular matrix structural constituent
1.55 4.84e-02 GO:0032403 protein complex binding
1.35 3.39e-02 GO:0005509 calcium ion binding
1.33 3.58e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.30 7.24e-03 GO:0005102 receptor binding
1.11 2.68e-05 GO:0005515 protein binding