Motif ID: SNAI1..3.p2

Z-value: 8.443


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI2chr8_-_49996353-0.351.8e-01Click!
SNAI3chr16_-_872802890.273.1e-01Click!
SNAI1chr20_+_48032918-0.077.9e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_60053050 27.973 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr8_+_120289735 21.610 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_-_166358792 18.894 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr20_+_48781457 18.656 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr7_-_22363036 17.411 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_27159462 16.912 NM_152365
C1orf172
chromosome 1 open reading frame 172
chr19_+_40431122 16.372 LSR
lipolysis stimulated lipoprotein receptor
chr8_-_144887876 16.112 NM_198488
FAM83H
family with sequence similarity 83, member H
chr2_-_166359016 15.528 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_+_6415259 15.432 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr1_+_1971762 14.626 NM_002744
PRKCZ
protein kinase C, zeta
chr2_-_166358951 13.751 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_+_43447262 13.716 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_7566698 13.702 NM_001080429
NM_020902
KIAA1543

KIAA1543

chr12_-_32940931 13.624 NM_001005242
NM_004572
PKP2

plakophilin 2

chr17_+_71033339 13.007 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr19_+_40431618 12.197 LSR
lipolysis stimulated lipoprotein receptor
chr1_-_159257486 12.195 F11R
F11 receptor
chr19_+_40431359 12.190 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr16_+_70217564 12.168 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr1_-_159257567 12.142 F11R
F11 receptor
chr1_+_181422016 12.136 LAMC2
laminin, gamma 2
chr1_-_159257595 12.110 NM_016946
F11R
F11 receptor
chr1_+_181421984 12.079 LAMC2
laminin, gamma 2
chr16_+_67236730 11.744 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr5_+_68824143 11.643 OCLN
occludin
chr8_+_102574012 11.558 GRHL2
grainyhead-like 2 (Drosophila)
chr4_-_35922288 11.460 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_199130571 11.356 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr17_+_35148084 11.019 NM_001030002
GRB7
growth factor receptor-bound protein 7
chr17_+_35147738 10.723 GRB7
growth factor receptor-bound protein 7
chr8_+_102573837 10.680 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr8_+_144888275 10.619 LOC100128338
hypothetical LOC100128338
chr18_+_27332024 10.577 NM_001943
DSG2
desmoglein 2
chr17_+_35147697 10.428 NM_005310
GRB7
growth factor receptor-bound protein 7
chr1_+_181421796 10.151 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr16_-_66827449 10.129 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr5_+_68746694 10.050 NM_001038603
MARVELD2
MARVEL domain containing 2
chr19_+_43447078 10.019 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr16_-_4927057 9.941 NM_002705
PPL
periplakin
chr11_+_120828058 9.862 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_+_26839143 9.769 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr11_+_384238 9.716 PKP3
plakophilin 3
chr19_-_60587414 9.670 NM_001190764
LOC388564
hypothetical protein LOC388564
chr8_-_81246215 9.552 NM_001025253
NM_005079
TPD52

tumor protein D52

chr11_+_120828275 9.380 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_+_74197473 9.310 LOC441086
hypothetical LOC441086
chr21_-_42060266 9.261 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr21_-_42060334 9.238 RIPK4
receptor-interacting serine-threonine kinase 4
chr14_+_69415880 9.107 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chr14_-_70345485 9.088 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr16_+_67328805 9.009 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr8_+_82807218 8.889 NM_152284
CHMP4C
chromatin modifying protein 4C
chr1_+_27541086 8.757 SYTL1
synaptotagmin-like 1
chr7_-_97868101 8.720 BAIAP2L1
BAI1-associated protein 2-like 1
chr17_-_37196463 8.670 NM_002230
NM_021991
JUP

junction plakoglobin

chr19_+_43446937 8.619 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr17_+_7225088 8.611 NM_003985
TNK1
tyrosine kinase, non-receptor, 1
chr6_-_10527772 8.566 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_27541049 8.498 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr10_-_134940315 8.446 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr6_-_30151526 8.446 NM_170769
NM_025236
RNF39

ring finger protein 39

chr2_+_54638957 8.334 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr19_-_10558906 8.277 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr16_+_67328715 8.213 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_+_24518398 8.168 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr7_-_1562272 8.165 NM_001097620
TMEM184A
transmembrane protein 184A
chr18_-_72973750 8.109 NM_001025100
NM_001025101
MBP

myelin basic protein

chr7_-_97868362 8.076 NM_018842
BAIAP2L1
BAI1-associated protein 2-like 1
chr16_+_67236699 8.054 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr6_+_54819527 8.023 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr4_+_155884600 8.006 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr18_+_19706979 7.898 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr18_-_45975163 7.806 NM_001080467
MYO5B
myosin VB
chr1_+_3360880 7.706 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr4_-_11039600 7.685 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr17_+_9489578 7.653 NM_153210
USP43
ubiquitin specific peptidase 43
chr12_-_51585004 7.645 NM_002273
KRT8
keratin 8
chr1_+_29086156 7.625 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr11_-_117628211 7.525 NM_198275
MPZL3
myelin protein zero-like 3
chr19_+_40431678 7.520 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_29086206 7.492 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_27113018 7.305 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr12_-_6354650 7.283 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr16_+_67328737 7.258 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_-_136913235 7.257 MAP7
microtubule-associated protein 7
chr15_+_92575767 7.255 MCTP2
multiple C2 domains, transmembrane 2
chr7_+_29570024 7.238 PRR15
proline rich 15
chr4_+_155884564 7.081 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr8_+_95722448 7.026 ESRP1
epithelial splicing regulatory protein 1
chr1_-_199635057 6.998 LAD1
ladinin 1
chr21_-_41140908 6.912 NM_001389
DSCAM
Down syndrome cell adhesion molecule
chr3_+_190990142 6.837 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr1_-_208046011 6.818 NM_006147
IRF6
interferon regulatory factor 6
chr21_+_17807167 6.815 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr16_+_67328693 6.767 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr14_-_60817621 6.707


chr1_-_27211913 6.698 NM_052943
FAM46B
family with sequence similarity 46, member B
chr11_+_66580861 6.661 NM_014578
RHOD
ras homolog gene family, member D
chr1_+_24518501 6.605 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr18_-_72973698 6.532 MBP
myelin basic protein
chr1_-_199635339 6.531 LAD1
ladinin 1
chr16_-_86082818 6.526 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr15_+_38923470 6.521 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_-_6585268 6.453 KLHL21
kelch-like 21 (Drosophila)
chr2_+_17585462 6.445 VSNL1
visinin-like 1
chr14_-_60817946 6.424


chr17_-_37034288 6.420 NM_000422
KRT17
keratin 17
chr1_-_55039458 6.406 NM_001114108
NM_017904
TTC22

tetratricopeptide repeat domain 22

chr5_-_60175798 6.391 NM_001104558
NM_024930
ELOVL7

ELOVL family member 7, elongation of long chain fatty acids (yeast)

chr11_-_64368616 6.361 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr4_-_9632192 6.343 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr14_-_54438913 6.339 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr14_-_66948523 6.327 NM_016445
PLEK2
pleckstrin 2
chr12_-_6354818 6.309 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr14_-_66948612 6.255 PLEK2
pleckstrin 2
chr11_+_32808045 6.168 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_+_40224480 6.158 HPN
hepsin
chr2_+_17585287 6.145 NM_003385
VSNL1
visinin-like 1
chr4_+_152549776 6.136 NM_001109977
FAM160A1
family with sequence similarity 160, member A1
chr17_+_72789086 6.077 NM_001113491
SEPT9
septin 9
chr20_-_6051562 5.952 FERMT1
fermitin family member 1
chr19_+_40299058 5.919 FXYD3
FXYD domain containing ion transport regulator 3
chr2_-_224410444 5.917 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chrX_+_130985316 5.894 NM_001042452
MST4
serine/threonine protein kinase MST4
chr6_+_34964999 5.872 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr14_-_60817663 5.827 TMEM30B
transmembrane protein 30B
chr11_+_384199 5.765 NM_007183
PKP3
plakophilin 3
chr20_-_60375695 5.749 NM_005560
LAMA5
laminin, alpha 5
chr1_+_154297588 5.747 NM_020387
RAB25
RAB25, member RAS oncogene family
chr10_-_62163083 5.736 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr8_-_127639647 5.689 FAM84B
family with sequence similarity 84, member B
chr15_+_38923914 5.678 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr1_-_57057956 5.675 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr11_+_129534983 5.638 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr3_-_48446405 5.623 NM_001130082
PLXNB1
plexin B1
chr12_+_6926014 5.599 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_-_40858775 5.593 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr16_+_56211410 5.591 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr9_-_111300350 5.572 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr3_+_46996150 5.571 NM_015175
NBEAL2
neurobeachin-like 2
chr5_-_59819642 5.568 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_139750311 5.531 NM_001008749
RAB19
RAB19, member RAS oncogene family
chr5_+_59819761 5.503 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr3_-_112796855 5.502 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr2_-_224410544 5.490 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr3_+_10832867 5.477 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr11_+_63412562 5.474 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr14_-_60818263 5.447 NM_001017970
TMEM30B
transmembrane protein 30B
chrX_-_106336199 5.439 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr8_+_95722516 5.430 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr19_+_40224457 5.425 HPN
hepsin
chr8_+_27238979 5.398 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr6_+_36206239 5.374 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr19_-_12747263 5.357 HOOK2
hook homolog 2 (Drosophila)
chr8_+_95722575 5.350 ESRP1
epithelial splicing regulatory protein 1
chr6_+_30958672 5.287 DDR1
discoidin domain receptor tyrosine kinase 1
chr21_-_41140457 5.278 DSCAM
Down syndrome cell adhesion molecule
chr9_+_35663852 5.271 NM_001216
CA9
carbonic anhydrase IX
chr11_+_45900731 5.214 GYLTL1B
glycosyltransferase-like 1B
chr6_+_7486891 5.201 DSP
desmoplakin
chr22_+_38720881 5.189 NM_138435
FAM83F
family with sequence similarity 83, member F
chr2_+_231610438 5.178 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr12_+_68419446 5.132 NM_175623
NM_175625
RAB3IP

RAB3A interacting protein (rabin3)

chr2_-_208342296 5.128 NM_003468
FZD5
frizzled homolog 5 (Drosophila)
chr14_-_23106372 5.069 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr1_+_46418786 5.055 TSPAN1
tetraspanin 1
chr10_+_8137356 5.009 GATA3
GATA binding protein 3
chr3_-_49434874 5.001 AMT
aminomethyltransferase
chr5_+_76150588 4.984 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr20_-_3097070 4.965 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr12_+_51629164 4.922 KRT18
keratin 18
chr15_-_32398220 4.919 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_+_149221122 4.909 NM_003568
ANXA9
annexin A9
chr15_+_88529122 4.902 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_+_129534922 4.864 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr14_-_60817709 4.845 TMEM30B
transmembrane protein 30B
chr12_+_51628921 4.830 NM_199187
NM_000224
KRT18

keratin 18

chr4_+_85723080 4.788 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr4_-_74704964 4.747 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr19_-_12747421 4.742 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr1_-_1840564 4.730 NM_178545
TMEM52
transmembrane protein 52
chr17_-_68769613 4.710 NM_001129885
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr8_-_144726064 4.700 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr1_-_54256390 4.699 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr20_+_31059174 4.688 BPIL1
bactericidal/permeability-increasing protein-like 1
chr2_-_162883062 4.669 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr4_+_8251818 4.661 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr7_+_29569913 4.658 NM_175887
PRR15
proline rich 15
chr5_+_78567604 4.651 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr17_+_71229191 4.651 ITGB4
integrin, beta 4
chr11_+_551449 4.619 NM_001143994
NM_003475
RASSF7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr5_+_68823874 4.612 NM_002538
OCLN
occludin
chr13_-_113066366 4.607 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr18_+_27281729 4.551 NM_001944
DSG3
desmoglein 3
chr7_+_143683365 4.531 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr7_-_142816019 4.523 NM_005232
EPHA1
EPH receptor A1
chr17_-_71385651 4.465 TRIM47
tripartite motif containing 47
chr8_-_79880095 4.459 NM_000880
IL7
interleukin 7
chr19_+_50535837 4.445 NM_177417
KLC3
kinesin light chain 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 2.31e-06 GO:0005737 cytoplasm
1.78 1.00e-02 GO:0045095 keratin filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.06 3.31e-02 GO:0005515 protein binding