Motif ID: RORA.p2

Z-value: 0.573


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RORAchr15_-_587069340.524.0e-02Click!


Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_22825148 0.797 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr1_-_233879617 0.716 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr3_+_9919295 0.659 NM_153483
IL17RE
interleukin 17 receptor E
chr4_-_186969202 0.638 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr17_-_46140015 0.572 NM_052855
ANKRD40
ankyrin repeat domain 40
chr7_+_101715137 0.560 SH2B2
SH2B adaptor protein 2
chr14_-_69725342 0.470 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr7_+_101715110 0.464 NM_020979
SH2B2
SH2B adaptor protein 2
chr10_-_52315390 0.446 A1CF
APOBEC1 complementation factor
chr3_-_24511180 0.436 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr3_-_24511456 0.380 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr1_+_67404756 0.335 NM_144701
IL23R
interleukin 23 receptor
chr11_-_2116048 0.309 IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_-_115877104 0.297 AMBP
alpha-1-microglobulin/bikunin precursor
chr10_-_52315436 0.289 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr3_-_127382051 0.265 ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr2_+_27358800 0.258 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr6_+_32229278 0.256 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr10_+_102285690 0.244 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr1_+_40635058 0.240 NM_001198980
SMAP2
small ArfGAP2
chr11_-_70350509 0.233 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr19_+_7607976 0.232 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr17_-_30414789 0.230 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr15_-_54322767 0.215 NM_022841
RFX7
regulatory factor X, 7
chr6_+_32229599 0.205 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr15_-_63457378 0.204 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr6_-_24491498 0.202 NM_001195610
DCDC2
doublecortin domain containing 2
chr18_-_54447168 0.200 NM_052947
ALPK2
alpha-kinase 2
chr17_-_36113502 0.195 NM_019016
KRT24
keratin 24
chr17_-_31332568 0.190 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr11_+_2116486 0.187


chr7_+_18501876 0.177 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr11_-_2116360 0.173 IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_-_154210341 0.168 C5orf4
chromosome 5 open reading frame 4
chr16_+_1773004 0.164 NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr10_+_102285562 0.162 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr2_+_121271336 0.162 NM_005270
GLI2
GLI family zinc finger 2
chr14_-_22825072 0.161 HOMEZ
homeobox and leucine zipper encoding
chr12_+_54700955 0.155 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr16_+_1772929 0.155 NM_012225
NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr16_+_16233979 0.149 NOMO2
NODAL modulator 2
chr17_+_68672705 0.148 NM_001050
SSTR2
somatostatin receptor 2
chr11_-_47572478 0.143 NM_031909
C1QTNF4
C1q and tumor necrosis factor related protein 4
chr1_-_40930295 0.143 LOC100130557
hypothetical LOC100130557
chr11_-_119514011 0.142 TRIM29
tripartite motif containing 29
chr16_-_1772305 0.142 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr11_-_2116775 0.134 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_+_106967283 0.131 ELMOD1
ELMO/CED-12 domain containing 1
chr1_-_176205970 0.131 SEC16B
SEC16 homolog B (S. cerevisiae)
chr5_+_38294417 0.130 EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr16_+_16233989 0.127 NOMO2
NODAL modulator 2
chrX_+_10084984 0.125 NM_001830
CLCN4
chloride channel 4
chr19_-_60272708 0.125 NM_138412
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr5_+_38294289 0.120 NM_152403
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr11_+_106967165 0.118 ELMOD1
ELMO/CED-12 domain containing 1
chr6_+_43846735 0.118 VEGFA
vascular endothelial growth factor A
chrX_-_71443725 0.113 NM_001144886
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr1_+_46413335 0.112 NM_005727
TSPAN1
tetraspanin 1
chr12_-_54497770 0.107 SARNP
SAP domain containing ribonucleoprotein
chr16_+_16233972 0.107 NOMO2
NODAL modulator 2
chr3_-_127382093 0.106 NM_012190
ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr8_+_120289735 0.104 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr5_+_38294613 0.103


chr6_-_155677303 0.102 NM_016020
TFB1M
transcription factor B1, mitochondrial
chr14_-_34661156 0.101 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr16_+_16233996 0.100 NOMO1
NODAL modulator 1
chr11_+_13255967 0.098 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_55869996 0.098 NM_001002907
OR8K1
olfactory receptor, family 8, subfamily K, member 1
chr17_-_23721430 0.097 VTN
vitronectin
chr1_+_227506751 0.096 NM_006542
SPHAR
S-phase response (cyclin related)
chr11_-_6418705 0.096 NM_000613
HPX
hemopexin
chr8_-_142307854 0.094 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr6_-_112033752 0.094 TRAF3IP2
TRAF3 interacting protein 2
chr4_+_39084867 0.093 NM_175737
KLB
klotho beta
chr2_-_154043403 0.093 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_+_43846372 0.092 VEGFA
vascular endothelial growth factor A
chr7_+_128795280 0.092 AHCYL2
adenosylhomocysteinase-like 2
chr16_+_16233955 0.091 NOMO2
NODAL modulator 2
chr16_+_16234008 0.090 NOMO1
NODAL modulator 1
chr1_-_176205672 0.090 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_-_155677254 0.089 TFB1M
transcription factor B1, mitochondrial
chr22_-_31732648 0.088 NM_003490
NM_133633
SYN3

synapsin III

chr6_+_26212082 0.088 NM_003542
HIST1H4C
histone cluster 1, H4c
chr5_-_154210350 0.088 C5orf4
chromosome 5 open reading frame 4
chr16_-_1772577 0.087 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr15_-_43209348 0.083 NM_144565
DUOXA1
dual oxidase maturation factor 1
chr17_+_7495436 0.082 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr10_-_21475493 0.081 NM_001010896
NM_001177483
C10orf113

chromosome 10 open reading frame 113

chr12_-_40824699 0.081 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr16_-_88623809 0.080 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr7_+_128795178 0.079 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr6_+_43845915 0.078 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_003376
VEGFA















vascular endothelial growth factor A















chr1_+_28637247 0.075 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr3_-_185578621 0.073 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr2_-_215711313 0.072 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr17_+_37941790 0.072 NAGLU
N-acetylglucosaminidase, alpha
chr11_+_13255952 0.071 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr22_+_20101661 0.070 NM_015094
HIC2
hypermethylated in cancer 2
chr6_+_15353681 0.069 JARID2
jumonji, AT rich interactive domain 2
chr12_+_2792047 0.069 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr15_-_50051239 0.068 NM_138792
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr11_-_64283945 0.068 PYGM
phosphorylase, glycogen, muscle
chr19_+_47073029 0.066 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr1_-_203985963 0.065 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_134209628 0.062 C5orf24
chromosome 5 open reading frame 24
chr5_-_150501393 0.061 NM_001193544
ANXA6
annexin A6
chr12_+_54910086 0.060 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr14_-_74458897 0.058 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr2_-_30883775 0.058 NM_144575
CAPN13
calpain 13
chr18_+_53967544 0.058 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr2_+_138975946 0.057


chr16_-_28210867 0.057


chr17_-_17426469 0.056 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chrX_-_2892288 0.055 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr1_-_246869181 0.055 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr7_+_111850367 0.054 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr6_+_43845875 0.053 VEGFA
vascular endothelial growth factor A
chrX_-_108611940 0.052 NM_001522
GUCY2F
guanylate cyclase 2F, retinal
chr4_+_155707089 0.051 FGB
fibrinogen beta chain
chr6_-_136889436 0.051 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr12_-_54497751 0.051 SARNP
SAP domain containing ribonucleoprotein
chr4_+_85723080 0.051 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr6_+_43846155 0.050 VEGFA
vascular endothelial growth factor A
chr8_-_72436832 0.048 EYA1
eyes absent homolog 1 (Drosophila)
chr12_+_25096472 0.047 NM_006152
LRMP
lymphoid-restricted membrane protein
chr1_-_203985932 0.047


chr14_+_93562500 0.047 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr20_-_1257782 0.047 SDCBP2
syndecan binding protein (syntenin) 2
chr17_-_17426416 0.046 PEMT
phosphatidylethanolamine N-methyltransferase
chr19_-_10540620 0.045 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr11_+_55776251 0.044 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr22_+_40286957 0.042 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr17_+_37941715 0.042 NAGLU
N-acetylglucosaminidase, alpha
chr1_+_78243181 0.041 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_+_38005875 0.041 NM_001170791
FAM82A1
family with sequence similarity 82, member A1
chr1_+_44217435 0.041 NM_003780
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr2_-_138762909 0.039


chr1_-_201162938 0.038 KLHL12
kelch-like 12 (Drosophila)
chr10_-_105835609 0.038 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr12_-_21439637 0.038 NM_134431
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr22_+_20068039 0.038 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr6_+_42991704 0.038 NM_138296
PTCRA
pre T-cell antigen receptor alpha
chr6_-_112033775 0.038 TRAF3IP2
TRAF3 interacting protein 2
chr2_+_170742900 0.037 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr9_-_35093189 0.037 STOML2
stomatin (EPB72)-like 2
chr15_-_50270856 0.037 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr17_+_7474128 0.036 SHBG
sex hormone-binding globulin
chr2_-_15999154 0.036 MYCNOS
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand
chr19_-_3930828 0.036 EEF2
eukaryotic translation elongation factor 2
chr22_-_18807805 0.033 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr7_-_150385912 0.032 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chr6_+_37429800 0.032 RNF8
ring finger protein 8
chr19_-_10352172 0.031 TYK2
tyrosine kinase 2
chr16_-_1772572 0.030 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr5_+_134209444 0.029 NM_001135586
C5orf24
chromosome 5 open reading frame 24
chr12_+_119617060 0.029


chr5_+_81636921 0.029 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr1_-_201422533 0.029 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_-_40411418 0.029 NM_152481
FAM187B
family with sequence similarity 187, member B
chr1_-_148936123 0.029 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr1_-_159413833 0.028 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr1_+_17719405 0.028 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_158654464 0.028 TULP4
tubby like protein 4
chr1_-_201422490 0.027 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_148868713 0.026 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr1_-_150328153 0.026 NM_001008536
TCHHL1
trichohyalin-like 1
chr12_+_49522967 0.026 NM_182559
TMPRSS12
transmembrane (C-terminal) protease, serine 12
chr11_+_13255948 0.026 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr1_+_170017430 0.026 METTL13
methyltransferase like 13
chr12_-_55637648 0.025 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr11_+_106967017 0.025 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr2_-_228206045 0.025 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr19_-_10540328 0.025 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr11_+_13255836 0.025 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr19_+_8384181 0.025 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr4_-_151990061 0.024 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr17_-_36981830 0.024 NM_000226
KRT9
keratin 9
chr4_+_52612197 0.024 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr14_+_19598043 0.023 NM_001004717
OR4L1
olfactory receptor, family 4, subfamily L, member 1
chr10_-_100164877 0.023 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr12_-_51887266 0.023 NM_000889
ITGB7
integrin, beta 7
chr1_+_149877955 0.023 SNX27
sorting nexin family member 27
chr1_-_16034928 0.022 FLJ37453
hypothetical LOC729614
chr6_+_4781330 0.021 NM_001143970
CDYL
chromodomain protein, Y-like
chr7_-_42938255 0.021 PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr12_-_46405477 0.021 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr1_-_246503738 0.020 NM_001004695
OR2T33
olfactory receptor, family 2, subfamily T, member 33
chr15_-_63871492 0.019 DENND4A
DENN/MADD domain containing 4A
chr1_-_155053124 0.019 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr2_-_191580567 0.018 STAT1
signal transducer and activator of transcription 1, 91kDa
chr6_+_37429776 0.018 RNF8
ring finger protein 8
chr16_-_45735333 0.018 NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr1_-_51583281 0.017 NM_001144832
TTC39A
tetratricopeptide repeat domain 39A
chr12_-_51887318 0.016 ITGB7
integrin, beta 7
chr2_+_119416214 0.016 NM_006770
MARCO
macrophage receptor with collagenous structure
chr15_-_31999815 0.016


chr15_+_100319349 0.015 LOC100134445
WASH1
WASH3P
hypothetical LOC100134445
WAS protein family homolog 1
WAS protein family homolog 3 pseudogene
chr10_+_18081223 0.014 NM_001098844
FAM23A
family with sequence similarity 23, member A
chr11_-_128567302 0.014 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr10_-_64698831 0.013 NM_004241
JMJD1C
jumonji domain containing 1C

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
70.94 3.42e-03 GO:0034314 Arp2/3 complex-mediated actin nucleation
47.30 1.68e-02 GO:0045010 actin nucleation

Nothing significant found in compartment category.

Nothing significant found in function category.