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• Activity deltas table
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Motif ID: RXRG_dimer.p3

Z-value: 1.071

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_+_116205830	2.076	NM_000040	APOC3	apolipoprotein C-III
chr12_-_6535481	2.076	NM_001039670 NM_001193457 NM_080730	IFFO1	intermediate filament family orphan 1
chr5_+_92944680	2.042	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr2_+_138438277	1.462	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr11_-_116213511	1.442	NM_000039	APOA1	apolipoprotein A-I
chr5_+_80292313	1.432	NM_006909	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2
chr6_+_30702586	1.376	NM_024909 NM_001031722 NM_001190724	ATAT1	alpha tubulin acetyltransferase 1
chr6_+_144040751	1.236	NM_001100164 NM_001100165	PHACTR2	phosphatase and actin regulator 2
chr16_-_86527608	1.192	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr12_+_54910767	1.171	NM_001135195	SLC39A5	solute carrier family 39 (metal ion transporter), member 5
chr7_-_100630912	1.071	NM_178176	MOGAT3	monoacylglycerol O-acyltransferase 3
chr16_+_4654710	1.006		MGRN1	mahogunin, ring finger 1
chr20_-_19981005	0.942		CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr5_-_42847716	0.941	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr2_+_73294852	0.917	NM_006062	SMYD5	SMYD family member 5
chr2_-_27966715	0.894	NM_022128	RBKS	ribokinase
chr2_+_219354692	0.881	NM_000784	CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1
chr12_+_119900677	0.879		HNF1A	HNF1 homeobox A
chr20_+_41621079	0.864	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr20_+_19981157	0.861	NM_015585	C20orf26	chromosome 20 open reading frame 26
chr1_+_78126787	0.851	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr18_-_44731078	0.841	NM_001190821 NM_005904	SMAD7	SMAD family member 7
chr2_+_218992053	0.834	NM_007127	VIL1	villin 1
chr16_+_79829794	0.827	NM_017429	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr18_-_44730706	0.793		SMAD7	SMAD family member 7
chr20_+_41621119	0.789		SGK2	serum/glucocorticoid regulated kinase 2
chr10_-_52315390	0.758		A1CF	APOBEC1 complementation factor
chr19_+_54708302	0.736		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr2_+_219141761	0.718	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr2_-_206732348	0.712	NM_005006	NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_+_206732575	0.698		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr19_+_54708312	0.695		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr1_+_144439069	0.694	NM_002614	PDZK1	PDZ domain containing 1
chr12_+_119900931	0.674	NM_000545	HNF1A	HNF1 homeobox A
chr2_+_206732562	0.672	NM_001037663 NM_001959 NM_021121	EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr6_+_142510075	0.658		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr1_+_61320213	0.647	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr10_-_21854616	0.629	NM_207371	C10orf140	chromosome 10 open reading frame 140
chr17_-_33178987	0.626		HNF1B	HNF1 homeobox B
chr2_+_27966985	0.626	NM_199193 NM_199194 NM_004899 NM_199191 NM_199192	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr11_+_117948301	0.615	NM_001142281 NM_001655	ARCN1	archain 1
chr20_+_55569542	0.611	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr3_-_49424322	0.603		RHOA	ras homolog gene family, member A
chr11_+_117948350	0.599		ARCN1	archain 1
chr2_+_27967116	0.590		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr3_-_114947681	0.588	NM_025146	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_+_142510094	0.586	NM_016485	VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr2_+_27967102	0.582		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr2_+_161725172	0.571		TANK	TRAF family member-associated NFKB activator
chr1_-_172153087	0.568	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_-_33179118	0.563	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr3_-_49424413	0.561		RHOA	ras homolog gene family, member A
chr9_+_103335983	0.557		RNF20	ring finger protein 20
chr10_-_52315436	0.550	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr6_+_142510108	0.548		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr2_+_198073358	0.547		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr3_-_49424380	0.538		RHOA	ras homolog gene family, member A
chr3_-_49424397	0.537		RHOA	ras homolog gene family, member A
chr3_-_49424427	0.534		RHOA	ras homolog gene family, member A
chr3_-_49424361	0.491		RHOA	ras homolog gene family, member A
chr17_+_7474128	0.489		SHBG	sex hormone-binding globulin
chr11_-_123261549	0.486	NM_001013743	TMEM225	transmembrane protein 225
chr18_+_45594326	0.468
chr6_+_142510034	0.454		VTA1	Vps20-associated 1 homolog (S. cerevisiae)
chr2_-_198072805	0.451		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr3_-_49424404	0.450		RHOA	ras homolog gene family, member A
chr22_+_22445035	0.449	NM_005940	MMP11	matrix metallopeptidase 11 (stromelysin 3)
chr10_+_102722275	0.445	NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_+_159021653	0.445		PKP4	plakophilin 4
chr2_+_27967159	0.440		BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)
chr14_-_74713062	0.438		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr14_-_74713086	0.433		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr2_-_219141199	0.416	NM_020935	USP37	ubiquitin specific peptidase 37
chr2_-_198072767	0.410		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr14_-_94693359	0.410		DICER1	dicer 1, ribonuclease type III
chr20_+_36095263	0.401	NM_021215	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr1_-_172153024	0.399		SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr4_+_30330963	0.393	NM_001173523 NM_002589 NM_032456 NM_032457	PCDH7	protocadherin 7
chr3_-_114947330	0.392		NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr14_-_74713088	0.391	NM_006827	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr9_+_103335964	0.390		RNF20	ring finger protein 20
chr2_+_219141546	0.388		RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_-_102487356	0.386		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr13_+_99539269	0.385	NM_000282 NM_001127692 NM_001178004	PCCA	propionyl CoA carboxylase, alpha polypeptide
chr19_+_16169664	0.382	NM_001130524 NM_032493	AP1M1	adaptor-related protein complex 1, mu 1 subunit
chr2_+_198072965	0.380	NM_002157	HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr6_-_2785682	0.379		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_+_198073257	0.366		HSPE1	heat shock 10kDa protein 1 (chaperonin 10)
chr14_-_74713039	0.360		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr19_+_41980248	0.358		LOC284408	hypothetical LOC284408
chr2_+_206732859	0.353		EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_-_218843109	0.342	NM_001087	AAMP	angio-associated, migratory cell protein
chr1_-_15784048	0.342	NM_024758	AGMAT	agmatine ureohydrolase (agmatinase)
chr17_+_3324096	0.339	NM_001128085	ASPA	aspartoacylase
chr20_+_36095621	0.339
chr10_+_685887	0.330		C10orf108	chromosome 10 open reading frame 108
chr14_+_94693744	0.328		FLJ45244	hypothetical locus FLJ45244
chr17_+_7474177	0.320	NM_001040 NM_001146279 NM_001146280 NM_001146281	SHBG	sex hormone-binding globulin
chr3_-_49424506	0.309		RHOA	ras homolog gene family, member A
chr11_+_117735502	0.309	NM_004788	UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr11_+_117735529	0.307		UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr8_-_81104938	0.304	NM_014018	MRPS28	mitochondrial ribosomal protein S28
chr14_-_20642214	0.304
chr8_+_22909305	0.297	NM_001160037	RHOBTB2	Rho-related BTB domain containing 2
chr3_-_49424529	0.295	NM_001664	RHOA	ras homolog gene family, member A
chr15_+_94674849	0.295	NM_021005	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr5_+_132237253	0.287	NM_052971	LEAP2	liver expressed antimicrobial peptide 2
chr12_+_105692466	0.284	NM_018157	RIC8B	resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr2_-_218843088	0.283		AAMP	angio-associated, migratory cell protein
chr12_+_65949327	0.282	NM_018448	CAND1	cullin-associated and neddylation-dissociated 1
chr18_-_45594206	0.275	NM_006111	ACAA2	acetyl-CoA acyltransferase 2
chr12_-_52407470	0.272	NM_001143682 NM_020898	CALCOCO1	calcium binding and coiled-coil domain 1
chr9_+_88086932	0.270
chr16_-_3433490	0.269	NM_152457	ZNF597	zinc finger protein 597
chr2_-_198073242	0.269	NM_199440	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr11_+_117735530	0.268		UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr1_-_120112989	0.268	NM_001166107 NM_005518	HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr1_-_95311031	0.267	NM_144988	ALG14	asparagine-linked glycosylation 14 homolog (S. cerevisiae)
chr14_-_74713012	0.267		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr12_+_65949414	0.266		CAND1	cullin-associated and neddylation-dissociated 1
chr2_-_218843039	0.265		AAMP	angio-associated, migratory cell protein
chr3_-_49178773	0.263	NM_022903	CCDC71	coiled-coil domain containing 71
chr2_-_64099935	0.260		VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae)
chr2_-_198072868	0.260	NM_002156	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr19_+_54708389	0.259		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr17_+_1592893	0.257		SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr20_+_30409649	0.255	NM_001164603 NM_015338	ASXL1	additional sex combs like 1 (Drosophila)
chr11_+_64079665	0.253	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr3_-_49178762	0.251		CCDC71	coiled-coil domain containing 71
chr19_+_54708247	0.246	NM_004107	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr9_+_114182216	0.244		HSDL2	hydroxysteroid dehydrogenase like 2
chr16_+_30617962	0.243	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr9_+_103335941	0.241	NM_019592	RNF20	ring finger protein 20
chr8_-_82769761	0.240	NM_001010893	SLC10A5	solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr11_+_117735558	0.238		UBE4A	ubiquitination factor E4A (UFD2 homolog, yeast)
chr20_-_32363268	0.235	NM_001161766	AHCY	adenosylhomocysteinase
chr3_-_49178738	0.230		CCDC71	coiled-coil domain containing 71
chr9_+_114182009	0.230	NM_001195822 NM_032303	HSDL2	hydroxysteroid dehydrogenase like 2
chr11_-_61415429	0.229	NM_021727	FADS3	fatty acid desaturase 3
chr1_+_45046740	0.222	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr4_+_30331289	0.222		PCDH7	protocadherin 7
chr20_+_36095552	0.219		RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr1_-_101263867	0.216	NM_001077394 NM_001077395 NM_015958	DPH5	DPH5 homolog (S. cerevisiae)
chr10_+_103995297	0.207	NM_004193	GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr2_+_218843358	0.205	NM_001077399 NM_015488	PNKD	paroxysmal nonkinesigenic dyskinesia
chr6_+_143813472	0.204	NM_003630	PEX3	peroxisomal biogenesis factor 3
chr12_+_67489063	0.203		MDM2	Mdm2 p53 binding protein homolog (mouse)
chr12_-_49708279	0.199	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_+_73954100	0.197	NM_004293	GDA	guanine deaminase
chr13_+_20612709	0.193		SAP18	Sin3A-associated protein, 18kDa
chr22_-_40194602	0.191	NM_032758	PHF5A	PHD finger protein 5A
chr2_-_19421852	0.187	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr20_+_42593849	0.185	NM_007066 NM_181804 NM_181805	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_153213454	0.184		SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr20_+_54400979	0.180	NM_001324	CSTF1	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr1_-_201411533	0.180	NM_004997	MYBPH	myosin binding protein H
chr2_-_24160683	0.171		TP53I3	tumor protein p53 inducible protein 3
chr20_-_36095236	0.171	NM_014657	TTI1	Tel2 interacting protein 1 homolog (S. pombe)
chr17_+_1592879	0.167	NM_000934 NM_001165921	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr12_-_117295095	0.166	NM_016281	TAOK3	TAO kinase 3
chr1_-_158579653	0.165		COPA	coatomer protein complex, subunit alpha
chr9_+_91123204	0.164	NM_024077	SECISBP2	SECIS binding protein 2
chr7_+_288195	0.164		FAM20C	family with sequence similarity 20, member C
chrX_+_105823723	0.161	NM_024539	RNF128	ring finger protein 128
chrX_+_38305634	0.159	NM_004615	TSPAN7	tetraspanin 7
chr1_-_158579680	0.159		COPA	coatomer protein complex, subunit alpha
chr19_-_40317829	0.149	NM_139284	LGI4	leucine-rich repeat LGI family, member 4
chr18_-_45593852	0.148		ACAA2	acetyl-CoA acyltransferase 2
chr10_+_103995248	0.148		GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr1_-_154147787	0.147	NM_006912	RIT1	Ras-like without CAAX 1
chr1_-_79244948	0.146	NM_022159	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1
chr14_-_94693418	0.146	NM_177438	DICER1	dicer 1, ribonuclease type III
chr9_+_73954206	0.146		GDA	guanine deaminase
chr1_+_158579685	0.143	NM_015331	NCSTN	nicastrin
chr10_-_62431203	0.142		RHOBTB1	Rho-related BTB domain containing 1
chr22_+_48927610	0.138	NM_001164106	MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr22_+_28493351	0.138	NM_001003684 NM_013387	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X
chr9_+_73954174	0.138		GDA	guanine deaminase
chr1_-_153213425	0.136		SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr4_+_109761170	0.135	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr14_+_23937766	0.135	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr9_+_73954237	0.133		GDA	guanine deaminase
chr1_-_158579583	0.131
chr1_-_149404954	0.129	NM_212551 NM_001136543	LYSMD1	LysM, putative peptidoglycan-binding, domain containing 1
chr19_-_55708936	0.128	NM_001114598	ASPDH	aspartate dehydrogenase domain containing
chr12_+_65949631	0.128		CAND1	cullin-associated and neddylation-dissociated 1
chr14_-_20636337	0.126		ZNF219	zinc finger protein 219
chr20_+_43943254	0.125	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr9_+_73954214	0.123		GDA	guanine deaminase
chr4_-_84150885	0.120		LIN54	lin-54 homolog (C. elegans)
chr15_-_98091118	0.119		LYSMD4	LysM, putative peptidoglycan-binding, domain containing 4
chr2_+_108432008	0.118	NM_181453	GCC2	GRIP and coiled-coil domain containing 2
chr17_+_38403935	0.118	NM_000988	RPL27	ribosomal protein L27
chr4_+_140806536	0.117		MGST2	microsomal glutathione S-transferase 2
chr3_-_52287297	0.116		WDR82	WD repeat domain 82
chr1_+_1351370	0.114	NM_001146685	TMEM88B	transmembrane protein 88B
chr8_+_67787444	0.114	NM_001033578	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr17_+_38403991	0.114		RPL27	ribosomal protein L27
chr11_+_86426518	0.112	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chr6_+_31731647	0.108	NM_019101	APOM	apolipoprotein M

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
20.47	3.31e-03	GO:0048199	vesicle targeting, to, from or within Golgi

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
30.70	1.67e-02	GO:0034366	spherical high-density lipoprotein particle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
27.29	3.07e-02	GO:0003706	ligand-regulated transcription factor activity