Motif ID: NRF1.p2

Z-value: 3.947


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290387650.485.9e-02Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_2330594 3.237 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr6_-_39305203 3.061 NM_003740
 KCNK5
potassium channel, subfamily K, member 5
chr13_-_78075683 2.897 NM_006237
 POU4F1
POU class 4 homeobox 1
chr16_-_2330712 2.753 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chrX_+_84385649 2.607 NM_021998
 ZNF711
zinc finger protein 711
chr16_-_2330738 2.554 NM_001089
 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chrX_-_153360789 2.550 NM_006014
 LAGE3
L antigen family, member 3
chr1_+_227473638 2.517 RAB4A
RAB4A, member RAS oncogene family
chr5_-_1647617 2.450 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr4_+_6726555 2.396 LOC93622
hypothetical LOC93622
chr6_-_31977747 2.362 NM_181842
 ZBTB12
zinc finger and BTB domain containing 12
chr12_-_52356123 2.328 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr1_+_165456572 2.325 NM_001198786
NM_002697
 POU2F1

POU class 2 homeobox 1

chr22_-_30071761 2.301 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr19_-_60462152 2.278 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr1_-_247119516 2.272 NM_001136036
 ZNF692
zinc finger protein 692
chr19_-_51097694 2.266 NM_001012643
 MYPOP
Myb-related transcription factor, partner of profilin
chr1_+_148603208 2.132 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr12_-_52356375 2.129 NM_005176
 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_-_31882558 2.126 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 81 entries
enrichment   p-value GO term description
3.39 3.63e-06 GO:0006405 RNA export from nucleus
3.39 2.85e-05 GO:0006406 mRNA export from nucleus
3.02 1.42e-05 GO:0051168 nuclear export
2.67 4.15e-02 GO:0031124 mRNA 3'-end processing
2.59 1.53e-04 GO:0051028 mRNA transport
2.56 2.32e-02 GO:0031123 RNA 3'-end processing
2.51 1.70e-04 GO:0050657 nucleic acid transport
2.51 1.70e-04 GO:0050658 RNA transport
2.51 1.70e-04 GO:0051236 establishment of RNA localization
2.49 1.38e-04 GO:0006403 RNA localization
2.46 5.30e-07 GO:0051169 nuclear transport
2.45 1.05e-06 GO:0006913 nucleocytoplasmic transport
2.33 1.68e-06 GO:0000375 RNA splicing, via transesterification reactions
2.32 4.91e-02 GO:0016072 rRNA metabolic process
2.31 5.03e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.31 5.03e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
2.22 3.70e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.16 1.01e-02 GO:0006333 chromatin assembly or disassembly
2.11 8.42e-04 GO:0034470 ncRNA processing
2.08 9.08e-16 GO:0006396 RNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
3.52 4.99e-02 GO:0005680 anaphase-promoting complex
2.44 1.55e-10 GO:0000785 chromatin
2.43 1.15e-02 GO:0031461 cullin-RING ubiquitin ligase complex
2.35 4.50e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.09 1.32e-12 GO:0044427 chromosomal part
2.04 1.62e-02 GO:0005681 spliceosomal complex
2.00 8.03e-13 GO:0005694 chromosome
2.00 2.07e-02 GO:0000793 condensed chromosome
1.98 5.05e-03 GO:0044454 nuclear chromosome part
1.96 4.23e-02 GO:0000151 ubiquitin ligase complex
1.94 1.82e-10 GO:0030529 ribonucleoprotein complex
1.84 3.28e-02 GO:0005840 ribosome
1.83 1.14e-02 GO:0000228 nuclear chromosome
1.82 2.52e-03 GO:0005759 mitochondrial matrix
1.74 4.48e-02 GO:0005813 centrosome
1.71 4.01e-17 GO:0005654 nucleoplasm
1.67 2.89e-22 GO:0031981 nuclear lumen
1.65 1.04e-25 GO:0044428 nuclear part
1.63 7.72e-25 GO:0070013 intracellular organelle lumen
1.61 3.05e-02 GO:0005815 microtubule organizing center

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.52 1.29e-02 GO:0042393 histone binding
1.97 3.23e-03 GO:0003682 chromatin binding
1.86 1.10e-14 GO:0003723 RNA binding
1.84 5.01e-03 GO:0019787 small conjugating protein ligase activity
1.81 1.94e-02 GO:0004842 ubiquitin-protein ligase activity
1.80 3.35e-03 GO:0016881 acid-amino acid ligase activity
1.76 3.10e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.76 4.59e-02 GO:0003713 transcription coactivator activity
1.64 7.46e-03 GO:0003712 transcription cofactor activity
1.63 8.25e-03 GO:0000988 protein binding transcription factor activity
1.63 8.25e-03 GO:0000989 transcription factor binding transcription factor activity
1.60 4.03e-03 GO:0016874 ligase activity
1.42 3.88e-18 GO:0003676 nucleic acid binding
1.34 4.53e-07 GO:0000166 nucleotide binding
1.33 1.18e-06 GO:0003677 DNA binding
1.30 1.03e-02 GO:0005524 ATP binding
1.29 1.11e-02 GO:0030554 adenyl nucleotide binding
1.29 1.49e-02 GO:0032559 adenyl ribonucleotide binding
1.28 6.58e-03 GO:0016740 transferase activity
1.26 1.16e-02 GO:0035639 purine ribonucleoside triphosphate binding