Motif ID: GATA6.p2

Z-value: 3.835


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_18003401-0.342.0e-01Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_70745615 20.025 NM_033496
HK1
hexokinase 1
chr7_-_100077072 18.168 NM_003227
TFR2
transferrin receptor 2
chr12_-_52975823 13.604 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_52975777 13.566 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr7_-_142369534 13.013 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr7_-_142369519 12.754 KEL
Kell blood group, metallo-endopeptidase
chr1_-_156923111 12.023 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_+_31782618 11.610 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr6_-_49712483 10.977 NM_000324
RHAG
Rh-associated glycoprotein
chr9_-_99740243 10.261 NM_197978
HEMGN
hemogen
chr1_-_27113018 9.474 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr16_-_87570716 9.425 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr11_+_118463906 9.210 NM_001024382
HMBS
hydroxymethylbilane synthase
chr12_+_52105131 8.159 AMHR2
anti-Mullerian hormone receptor, type II
chr1_+_43063817 7.967 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chrX_+_65152004 7.841


chr17_-_59437782 7.652 NM_000873
ICAM2
intercellular adhesion molecule 2
chr19_-_12858956 7.114 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr17_-_53764867 7.098


chr1_+_152560179 6.700 NM_080429
AQP10
aquaporin 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
7.56 3.71e-02 GO:0072378 blood coagulation, fibrin clot formation
4.60 1.59e-05 GO:0007586 digestion
3.74 7.96e-05 GO:0006805 xenobiotic metabolic process
3.74 7.96e-05 GO:0071466 cellular response to xenobiotic stimulus
3.71 9.20e-05 GO:0009410 response to xenobiotic stimulus
2.75 2.25e-03 GO:0008202 steroid metabolic process
2.74 2.47e-03 GO:0030168 platelet activation
2.66 3.47e-02 GO:0003013 circulatory system process
2.66 3.47e-02 GO:0008015 blood circulation
2.38 2.49e-04 GO:0007608 sensory perception of smell
2.13 5.05e-03 GO:0007606 sensory perception of chemical stimulus
2.07 1.07e-02 GO:0007596 blood coagulation
2.07 1.07e-02 GO:0050817 coagulation
2.05 1.26e-02 GO:0007599 hemostasis
2.04 1.49e-02 GO:0001775 cell activation
1.97 5.64e-03 GO:0048878 chemical homeostasis
1.92 3.27e-02 GO:0050878 regulation of body fluid levels
1.71 4.45e-02 GO:0042592 homeostatic process
1.66 3.37e-05 GO:0003008 system process
1.63 2.47e-06 GO:0065008 regulation of biological quality

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.64 5.62e-03 GO:0044421 extracellular region part
1.49 4.25e-04 GO:0005576 extracellular region
1.41 1.67e-07 GO:0071944 cell periphery
1.40 4.74e-07 GO:0005886 plasma membrane
1.23 6.32e-03 GO:0031224 intrinsic to membrane
1.21 3.40e-03 GO:0044425 membrane part
1.21 2.45e-02 GO:0016021 integral to membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.80 1.51e-02 GO:0019825 oxygen binding
2.43 4.76e-05 GO:0004984 olfactory receptor activity
1.73 7.67e-03 GO:0004930 G-protein coupled receptor activity
1.54 2.06e-02 GO:0004888 transmembrane receptor activity
1.53 1.72e-03 GO:0004872 receptor activity
1.39 3.44e-02 GO:0004871 signal transducer activity
1.39 3.44e-02 GO:0060089 molecular transducer activity