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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 1.260

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_44010543	1.789	NM_024015	HOXB4	homeobox B4
chr7_+_128257698	1.378	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr2_+_109112428	1.213	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr22_+_18081968	1.167	NM_002688	SEPT5	septin 5
chr1_-_31154023	1.165	NM_014654	SDC3	syndecan 3
chr6_-_85530617	0.995	NM_001080508	TBX18	T-box 18
chr2_-_144991386	0.971		ZEB2	zinc finger E-box binding homeobox 2
chr22_+_38075703	0.933	NM_004711 NM_145731	SYNGR1	synaptogyrin 1
chr13_-_37341859	0.927	NM_001135955 NM_001135956 NM_001135957 NM_001135958 NM_003306 NM_016179	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chr14_-_60022487	0.879	NM_174978	C14orf39	chromosome 14 open reading frame 39
chr5_-_88215034	0.863	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr19_+_45799060	0.844	NM_001042545	LTBP4	latent transforming growth factor beta binding protein 4
chr7_-_150283794	0.802	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_-_64416307	0.782		SPTB	spectrin, beta, erythrocytic
chr19_-_1518875	0.773	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr17_+_77582774	0.772	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_198377561	0.766	NM_006226	PLCL1	phospholipase C-like 1
chr7_-_150576660	0.764	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_-_122679387	0.727	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr1_-_32574185	0.722	NM_023009	MARCKSL1	MARCKS-like 1
chr17_+_78630793	0.670	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chrX_+_9392980	0.657	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr7_-_100331417	0.652	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr5_-_178704934	0.649		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr12_+_50271283	0.645	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr12_+_50586958	0.642		ACVRL1	activin A receptor type II-like 1
chr1_+_65763978	0.623		LEPR	leptin receptor
chr7_+_106472243	0.617	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr1_+_65763945	0.615	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr2_+_181553333	0.610	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr19_+_18391423	0.604
chr5_-_178705036	0.601	NM_014244 NM_021599	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr17_-_71747867	0.598	NM_052916	RNF157	ring finger protein 157
chr12_+_46133	0.592	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr7_-_106088565	0.589	NM_175884	FLJ36031	hypothetical protein FLJ36031
chr1_-_38243747	0.588	NM_004468	FHL3	four and a half LIM domains 3
chr17_-_44058612	0.588	NM_024017	HOXB9	homeobox B9
chr9_+_138341752	0.587	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr19_+_7891884	0.585		SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa
chr9_-_129701644	0.581	NM_013443	ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr15_-_81113676	0.580	NM_030594	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr1_+_41022066	0.575	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chrX_-_135161185	0.575	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr14_+_106009489	0.568		NCRNA00221	non-protein coding RNA 221
chr7_-_525556	0.568		PDGFA	platelet-derived growth factor alpha polypeptide
chr1_-_38243716	0.567		FHL3	four and a half LIM domains 3
chr2_+_10101081	0.564	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr19_+_14405216	0.562		PKN1	protein kinase N1
chr4_+_72271218	0.558	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr7_-_50828159	0.553		GRB10	growth factor receptor-bound protein 10
chr17_-_1029758	0.549	NM_021962	ABR	active BCR-related gene
chr7_-_130069399	0.544	NM_138693	KLF14	Kruppel-like factor 14
chr1_+_35507145	0.541	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr4_+_151218862	0.540	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr3_-_172660545	0.536	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr1_-_39877883	0.534		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr10_+_112394094	0.526	NM_001134363	RBM20	RNA binding motif protein 20
chr1_+_177261627	0.526		FAM20B	family with sequence similarity 20, member B
chr21_-_43368963	0.525	NM_000071	CBS	cystathionine-beta-synthase
chr22_+_18091065	0.525	NM_000407	GP1BB	glycoprotein Ib (platelet), beta polypeptide
chr6_+_135544138	0.524	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr1_+_199884072	0.524	NM_020443	NAV1	neuron navigator 1
chr1_-_39877928	0.522	NM_014571	HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr15_-_76890626	0.520	NM_014272	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr15_-_27901628	0.518		TJP1	tight junction protein 1 (zona occludens 1)
chr4_+_129951877	0.518		PHF17	PHD finger protein 17
chr2_+_42128521	0.512	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr9_-_129701695	0.511		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr13_-_113916066	0.510		RASA3	RAS p21 protein activator 3
chr1_-_109742020	0.506	NM_002959	SORT1	sortilin 1
chr2_-_236740710	0.504
chr6_+_99389300	0.503	NM_005604	POU3F2	POU class 3 homeobox 2
chr9_-_122679283	0.501		PHF19	PHD finger protein 19
chr19_+_16296734	0.500		KLF2	Kruppel-like factor 2 (lung)
chr16_-_53520208	0.496		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr4_+_81406765	0.495	NM_004464 NM_033143	FGF5	fibroblast growth factor 5
chr4_-_809879	0.494	NM_006651	CPLX1	complexin 1
chr4_-_109308893	0.494	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr6_-_46566969	0.492		RCAN2	regulator of calcineurin 2
chr19_+_60487345	0.491	NM_032430	BRSK1	BR serine/threonine kinase 1
chr4_-_25473528	0.491	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_+_15442100	0.490	NM_006765 NM_178234	TUSC3	tumor suppressor candidate 3
chr19_+_659766	0.490	NM_001040134 NM_002579	PALM	paralemmin
chr5_-_81082699	0.488	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr6_+_135544170	0.488		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr16_-_19803606	0.487	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr13_-_113916115	0.485		RASA3	RAS p21 protein activator 3
chr16_+_2016807	0.485	NM_001130012 NM_004785	SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_-_81910956	0.483	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr19_-_45888259	0.483	NM_004756	NUMBL	numb homolog (Drosophila)-like
chr1_+_117950029	0.481	NM_017709	FAM46C	family with sequence similarity 46, member C
chr7_-_156125876	0.479		C7orf13	chromosome 7 open reading frame 13
chr6_+_133604181	0.479	NM_004100 NM_172103 NM_172105	EYA4	eyes absent homolog 4 (Drosophila)
chr19_-_15172773	0.477	NM_000435	NOTCH3	notch 3
chr15_-_80125403	0.475	NM_032246	MEX3B	mex-3 homolog B (C. elegans)
chrX_+_153339814	0.475	NM_017514	PLXNA3	plexin A3
chr18_-_51406359	0.475		TCF4	transcription factor 4
chr1_-_182273114	0.470		GLT25D2	glycosyltransferase 25 domain containing 2
chr22_-_18384251	0.469	NM_001670	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome
chr6_+_99389318	0.467		POU3F2	POU class 3 homeobox 2
chr9_-_129701602	0.464		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr18_-_21186107	0.462	NM_015461	ZNF521	zinc finger protein 521
chr11_-_32413486	0.462		WT1	Wilms tumor 1
chr15_-_23659329	0.459	NM_024490	ATP10A	ATPase, class V, type 10A
chr19_-_3737382	0.459	NM_139354 NM_139355	MATK	megakaryocyte-associated tyrosine kinase
chr19_+_60487578	0.457		BRSK1	BR serine/threonine kinase 1
chr9_-_129701707	0.457		ST6GALNAC6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr13_-_113916159	0.455		RASA3	RAS p21 protein activator 3
chr19_+_3536541	0.454	NM_133261	GIPC3	GIPC PDZ domain containing family, member 3
chr15_+_38520594	0.452	NM_014952	BAHD1	bromo adjacent homology domain containing 1
chr22_-_20551937	0.452		MAPK1	mitogen-activated protein kinase 1
chr1_-_15723363	0.452	NM_001229 NM_032996	CASP9	caspase 9, apoptosis-related cysteine peptidase
chr1_-_11663762	0.452	NM_006341	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)
chr10_+_98582005	0.449	NM_001170765 NM_001170766	LCOR	ligand dependent nuclear receptor corepressor
chr2_+_102602579	0.448	NM_003048	SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr18_+_12397894	0.448	NM_001142405 NM_006553	SLMO1	slowmo homolog 1 (Drosophila)
chr22_-_20551722	0.447		MAPK1	mitogen-activated protein kinase 1
chr13_-_107317460	0.443	NM_001080396	FAM155A	family with sequence similarity 155, member A
chrX_-_152592450	0.443		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chrX_-_152591936	0.442	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr5_-_176857207	0.441	NM_005451 NM_203352 NM_213636	PDLIM7	PDZ and LIM domain 7 (enigma)
chr1_+_35507197	0.440		ZMYM4	zinc finger, MYM-type 4
chr8_+_16929116	0.439	NM_181723	EFHA2	EF-hand domain family, member A2
chr6_+_133604203	0.435		EYA4	eyes absent homolog 4 (Drosophila)
chr7_+_44754700	0.435		ZMIZ2	zinc finger, MIZ-type containing 2
chr1_+_246087230	0.434		TRIM58	tripartite motif containing 58
chr12_+_119562737	0.434	NM_001033677	CABP1	calcium binding protein 1
chr21_-_38210531	0.433	NM_002240	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6
chr11_+_279113	0.432	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr13_-_113916186	0.430	NM_007368	RASA3	RAS p21 protein activator 3
chr11_+_46359878	0.428	NM_001012333	MDK	midkine (neurite growth-promoting factor 2)
chr19_+_34994701	0.426	NM_001238	CCNE1	cyclin E1
chr2_+_120820140	0.426	NM_002193	INHBB	inhibin, beta B
chr7_-_150576634	0.426		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr22_+_42751487	0.425	NM_013327	PARVB	parvin, beta
chr18_-_21185968	0.423		ZNF521	zinc finger protein 521
chr7_-_81910740	0.421		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr2_-_236741352	0.420	NM_001485	GBX2	gastrulation brain homeobox 2
chr3_-_38666122	0.419	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr6_+_19945578	0.419	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr10_-_17536181	0.418	NM_001004470	ST8SIA6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr1_-_15723279	0.415		CASP9	caspase 9, apoptosis-related cysteine peptidase
chr7_+_156126157	0.411	NM_030936 NM_001184996	RNF32	ring finger protein 32
chr7_-_526005	0.411	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr1_+_78126787	0.411	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr9_-_13269562	0.410		MPDZ	multiple PDZ domain protein
chr17_+_56832492	0.408		TBX2	T-box 2
chr20_-_61600834	0.408	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr1_+_148788410	0.407	NM_019032 NM_025008	ADAMTSL4	ADAMTS-like 4
chr20_+_30814048	0.406		DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta
chr9_+_115678365	0.405	NM_133374	ZNF618	zinc finger protein 618
chr1_+_21708502	0.401		ALPL	alkaline phosphatase, liver/bone/kidney
chr7_+_154720547	0.399		INSIG1	insulin induced gene 1
chr3_-_39170105	0.399	NM_033027	CSRNP1	cysteine-serine-rich nuclear protein 1
chr19_+_16296632	0.398	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr7_+_93861808	0.396	NM_000089	COL1A2	collagen, type I, alpha 2
chr11_+_46359821	0.396		MDK	midkine (neurite growth-promoting factor 2)
chr17_+_56832255	0.396		TBX2	T-box 2
chr5_-_176857158	0.392		PDLIM7	PDZ and LIM domain 7 (enigma)
chr1_-_54644566	0.392	NM_018070 NM_145716	SSBP3	single stranded DNA binding protein 3
chr5_+_172000793	0.389	NM_001142651	NEURL1B	neuralized homolog 1B (Drosophila)
chr11_-_61415429	0.388	NM_021727	FADS3	fatty acid desaturase 3
chr14_-_57688560	0.388	NM_001001872	C14orf37	chromosome 14 open reading frame 37
chr8_-_72919161	0.386		MSC	musculin
chr7_+_44754978	0.384	NM_031449	ZMIZ2	zinc finger, MIZ-type containing 2
chr10_+_11099860	0.383	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr22_+_20101661	0.381	NM_015094	HIC2	hypermethylated in cancer 2
chr7_-_150576957	0.381		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr20_-_4177519	0.380	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr19_+_10261646	0.380	NM_003259	ICAM5	intercellular adhesion molecule 5, telencephalin
chr3_-_159306214	0.380
chr5_-_81082614	0.379		SSBP2	single-stranded DNA binding protein 2
chr19_+_10574055	0.376	NM_001145056	SLC44A2	solute carrier family 44, member 2
chr1_-_51198328	0.376		FAF1	Fas (TNFRSF6) associated factor 1
chr19_-_7896974	0.375	NM_206833	CTXN1	cortexin 1
chr11_-_32413635	0.374	NM_000378 NM_024424 NM_024426	WT1	Wilms tumor 1
chr10_+_11100075	0.372		CELF2	CUGBP, Elav-like family member 2
chr19_+_1226510	0.371	NM_017914	C19orf24	chromosome 19 open reading frame 24
chr11_+_46359781	0.371	NM_002391	MDK	midkine (neurite growth-promoting factor 2)
chr20_+_30813851	0.370	NM_006892 NM_175848 NM_175849	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta
chr3_-_39170038	0.370		CSRNP1	cysteine-serine-rich nuclear protein 1
chr2_+_200031333	0.370
chr19_+_540849	0.369	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr5_+_176493488	0.369		NSD1	nuclear receptor binding SET domain protein 1
chr17_+_58058774	0.368		MRC2	mannose receptor, C type 2
chr21_-_37260488	0.367		HLCS	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr8_+_72918889	0.366
chr11_-_2863536	0.363	NM_000076 NM_001122630 NM_001122631	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr4_-_10068055	0.362	NM_053042	ZNF518B	zinc finger protein 518B
chr10_-_126839000	0.360		CTBP2	C-terminal binding protein 2
chr2_-_200028977	0.359		SATB2	SATB homeobox 2
chr8_-_72919241	0.358	NM_005098	MSC	musculin
chr5_-_10814179	0.358		DAP	death-associated protein
chr16_-_1862162	0.358	NM_001163560	C16orf73	chromosome 16 open reading frame 73
chr14_-_57688669	0.358		C14orf37	chromosome 14 open reading frame 37
chr3_-_159306532	0.357	NM_001163678 NM_003030 NM_006884	SHOX2	short stature homeobox 2
chr5_-_10814344	0.356	NM_004394	DAP	death-associated protein
chr16_+_1143241	0.355	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr7_+_150387649	0.354		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr12_-_123023312	0.353		CCDC92	coiled-coil domain containing 92

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.21	2.56e-21	GO:0050794	regulation of cellular process
1.20	8.59e-21	GO:0050789	regulation of biological process
1.18	3.28e-18	GO:0065007	biological regulation
1.11	2.25e-15	GO:0009987	cellular process
1.35	2.65e-15	GO:0010468	regulation of gene expression
1.30	2.75e-15	GO:0060255	regulation of macromolecule metabolic process
1.28	1.11e-14	GO:0031323	regulation of cellular metabolic process
1.24	2.45e-14	GO:0044260	cellular macromolecule metabolic process
1.59	5.62e-14	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.35	7.46e-14	GO:0010556	regulation of macromolecule biosynthetic process
1.36	9.08e-14	GO:0051252	regulation of RNA metabolic process
1.35	9.61e-14	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.26	9.94e-14	GO:0019222	regulation of metabolic process
1.35	5.35e-13	GO:0048519	negative regulation of biological process
1.32	7.09e-13	GO:0009889	regulation of biosynthetic process
1.27	1.36e-12	GO:0080090	regulation of primary metabolic process
1.32	1.54e-12	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	1.54e-12	GO:0031326	regulation of cellular biosynthetic process
1.35	3.73e-12	GO:0048523	negative regulation of cellular process
1.35	4.12e-12	GO:0006355	regulation of transcription, DNA-dependent
1.44	4.81e-12	GO:0007399	nervous system development
1.21	6.40e-12	GO:0043170	macromolecule metabolic process
1.30	1.60e-11	GO:0051171	regulation of nitrogen compound metabolic process
1.17	8.64e-11	GO:0044237	cellular metabolic process
1.87	1.69e-10	GO:0016568	chromatin modification
1.31	2.44e-10	GO:0048522	positive regulation of cellular process
1.35	8.65e-10	GO:0006464	protein modification process
1.34	1.86e-09	GO:0043412	macromolecule modification
1.28	2.11e-09	GO:0048518	positive regulation of biological process
1.22	3.54e-09	GO:0032502	developmental process
1.63	5.07e-09	GO:0010629	negative regulation of gene expression
1.59	5.52e-09	GO:0010628	positive regulation of gene expression
1.23	1.09e-08	GO:0007275	multicellular organismal development
1.49	2.18e-08	GO:0022008	neurogenesis
1.15	2.25e-08	GO:0044238	primary metabolic process
1.57	2.74e-08	GO:0051254	positive regulation of RNA metabolic process
1.27	8.27e-08	GO:0044267	cellular protein metabolic process
1.42	9.13e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.54	2.16e-07	GO:0031327	negative regulation of cellular biosynthetic process
1.13	2.19e-07	GO:0008152	metabolic process
1.57	2.57e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.53	2.58e-07	GO:0009890	negative regulation of biosynthetic process
1.33	2.90e-07	GO:0023051	regulation of signaling
1.47	4.34e-07	GO:0048699	generation of neurons
1.38	4.82e-07	GO:0009893	positive regulation of metabolic process
1.39	7.70e-07	GO:0031325	positive regulation of cellular metabolic process
1.24	9.59e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49	1.31e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.42	1.67e-06	GO:0009892	negative regulation of metabolic process
1.22	1.80e-06	GO:0048856	anatomical structure development
1.44	1.87e-06	GO:0050793	regulation of developmental process
1.45	2.07e-06	GO:0006351	transcription, DNA-dependent
1.62	2.48e-06	GO:0006325	chromatin organization
1.53	2.61e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.00	3.04e-06	GO:0016569	covalent chromatin modification
1.57	3.44e-06	GO:0051253	negative regulation of RNA metabolic process
1.52	3.61e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.47	3.95e-06	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47	4.35e-06	GO:0051173	positive regulation of nitrogen compound metabolic process
1.22	4.75e-06	GO:0019538	protein metabolic process
1.35	4.94e-06	GO:0051239	regulation of multicellular organismal process
1.42	6.69e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.56	8.53e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.98	9.26e-06	GO:0016570	histone modification
1.23	1.35e-05	GO:0071842	cellular component organization at cellular level
1.64	1.89e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.26	1.92e-05	GO:0030154	cell differentiation
1.22	2.48e-05	GO:0048731	system development
1.50	3.14e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47	3.34e-05	GO:0030182	neuron differentiation
1.25	3.47e-05	GO:0048869	cellular developmental process
1.40	3.53e-05	GO:0048468	cell development
1.55	4.41e-05	GO:0007417	central nervous system development
1.41	4.61e-05	GO:0009891	positive regulation of biosynthetic process
1.49	4.79e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.22	5.04e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.36	6.30e-05	GO:0010646	regulation of cell communication
1.41	1.14e-04	GO:0031328	positive regulation of cellular biosynthetic process
2.21	1.48e-04	GO:0040029	regulation of gene expression, epigenetic
1.39	1.59e-04	GO:0031324	negative regulation of cellular metabolic process
1.54	1.88e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.44	2.19e-04	GO:0045595	regulation of cell differentiation
1.40	2.21e-04	GO:0051128	regulation of cellular component organization
1.46	2.82e-04	GO:0051276	chromosome organization
1.42	2.91e-04	GO:2000026	regulation of multicellular organismal development
1.19	2.94e-04	GO:0034641	cellular nitrogen compound metabolic process
1.23	3.37e-04	GO:0090304	nucleic acid metabolic process
1.17	3.44e-04	GO:0023052	signaling
1.26	4.49e-04	GO:0016070	RNA metabolic process
2.46	4.97e-04	GO:0016458	gene silencing
1.18	7.44e-04	GO:0006807	nitrogen compound metabolic process
1.26	1.76e-03	GO:0006996	organelle organization
1.73	1.80e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.34	1.84e-03	GO:0032774	RNA biosynthetic process
1.27	2.19e-03	GO:0009966	regulation of signal transduction
1.43	4.22e-03	GO:0048666	neuron development
1.39	4.43e-03	GO:0009790	embryo development
1.26	5.42e-03	GO:0009653	anatomical structure morphogenesis
1.46	5.73e-03	GO:0031175	neuron projection development
1.53	7.72e-03	GO:0007420	brain development
1.65	8.47e-03	GO:0050767	regulation of neurogenesis
1.39	8.50e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.54	8.84e-03	GO:0018193	peptidyl-amino acid modification
1.16	8.95e-03	GO:0016043	cellular component organization
1.36	1.72e-02	GO:0006468	protein phosphorylation
2.00	1.87e-02	GO:0043414	macromolecule methylation
1.15	1.99e-02	GO:0071840	cellular component organization or biogenesis
1.58	2.43e-02	GO:0051960	regulation of nervous system development
1.29	2.69e-02	GO:0006793	phosphorus metabolic process
1.29	2.69e-02	GO:0006796	phosphate metabolic process
1.46	2.70e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
2.59	2.72e-02	GO:0031047	gene silencing by RNA
1.42	3.01e-02	GO:0000904	cell morphogenesis involved in differentiation
1.46	3.61e-02	GO:0007409	axonogenesis
1.25	3.62e-02	GO:0035556	intracellular signal transduction
1.41	3.66e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.49	3.82e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.44	3.93e-02	GO:0048812	neuron projection morphogenesis
1.42	3.93e-02	GO:0019226	transmission of nerve impulse
1.42	3.93e-02	GO:0035637	multicellular organismal signaling
1.44	4.55e-02	GO:0032583	regulation of gene-specific transcription

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	1.38e-32	GO:0044424	intracellular part
1.13	1.49e-30	GO:0005622	intracellular
1.16	1.78e-21	GO:0043227	membrane-bounded organelle
1.24	3.42e-21	GO:0005634	nucleus
1.16	4.15e-21	GO:0043231	intracellular membrane-bounded organelle
1.14	7.54e-21	GO:0043226	organelle
1.14	3.29e-20	GO:0043229	intracellular organelle
1.14	1.40e-13	GO:0005737	cytoplasm
1.30	1.45e-09	GO:0044428	nuclear part
1.33	3.18e-09	GO:0031981	nuclear lumen
1.04	6.94e-08	GO:0044464	cell part
1.04	7.44e-08	GO:0005623	cell
2.46	2.19e-07	GO:0016585	chromatin remodeling complex
1.24	3.05e-06	GO:0070013	intracellular organelle lumen
1.13	4.31e-06	GO:0044444	cytoplasmic part
1.23	6.20e-06	GO:0031974	membrane-enclosed lumen
1.20	1.06e-05	GO:0043234	protein complex
1.23	1.24e-05	GO:0043233	organelle lumen
1.30	5.61e-05	GO:0005654	nucleoplasm
1.55	7.43e-05	GO:0045202	synapse
1.23	9.05e-05	GO:0005829	cytosol
2.60	1.04e-04	GO:0035770	RNA granule
1.12	1.71e-04	GO:0044446	intracellular organelle part
1.12	2.47e-04	GO:0044422	organelle part
1.42	4.22e-04	GO:0030054	cell junction
1.36	1.24e-03	GO:0044451	nucleoplasm part
1.33	2.32e-03	GO:0031982	vesicle
2.06	2.89e-03	GO:0008021	synaptic vesicle
1.14	3.34e-03	GO:0032991	macromolecular complex
1.57	1.05e-02	GO:0005667	transcription factor complex
1.31	1.32e-02	GO:0031410	cytoplasmic vesicle
1.44	1.37e-02	GO:0043005	neuron projection
1.31	1.95e-02	GO:0031988	membrane-bounded vesicle
1.49	2.40e-02	GO:0044456	synapse part
3.05	2.46e-02	GO:0070603	SWI/SNF-type complex
1.31	2.83e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.62	3.18e-02	GO:0031252	cell leading edge
3.11	3.72e-02	GO:0031519	PcG protein complex
2.54	4.30e-02	GO:0042641	actomyosin
1.84	4.33e-02	GO:0019717	synaptosome
2.40	4.38e-02	GO:0000118	histone deacetylase complex
1.59	4.77e-02	GO:0030425	dendrite

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	4.94e-25	GO:0005515	protein binding
1.11	1.09e-19	GO:0005488	binding
1.60	1.83e-16	GO:0030528	transcription regulator activity
1.53	1.08e-12	GO:0001071	nucleic acid binding transcription factor activity
1.53	1.08e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
1.30	1.40e-10	GO:0003677	DNA binding
1.24	1.70e-10	GO:0003676	nucleic acid binding
1.54	1.54e-08	GO:0043565	sequence-specific DNA binding
1.24	6.28e-06	GO:0000166	nucleotide binding
1.25	6.73e-06	GO:0008270	zinc ion binding
1.62	8.52e-06	GO:0000988	protein binding transcription factor activity
1.62	8.52e-06	GO:0000989	transcription factor binding transcription factor activity
1.62	1.41e-05	GO:0003712	transcription cofactor activity
1.68	2.17e-05	GO:0016564	transcription repressor activity
1.65	9.74e-05	GO:0008134	transcription factor binding
1.62	1.40e-04	GO:0016563	transcription activator activity
1.73	1.40e-03	GO:0010843	promoter binding
1.71	1.58e-03	GO:0000975	regulatory region DNA binding
1.71	1.58e-03	GO:0001067	regulatory region nucleic acid binding
1.71	1.58e-03	GO:0044212	transcription regulatory region DNA binding
1.21	2.53e-03	GO:0032553	ribonucleotide binding
1.21	2.53e-03	GO:0032555	purine ribonucleotide binding
1.19	2.83e-03	GO:0046914	transition metal ion binding
1.21	3.57e-03	GO:0017076	purine nucleotide binding
1.14	4.76e-03	GO:0046872	metal ion binding
1.79	6.22e-03	GO:0003714	transcription corepressor activity
1.44	7.77e-03	GO:0004674	protein serine/threonine kinase activity
1.20	9.06e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.13	1.01e-02	GO:0043167	ion binding
1.13	1.03e-02	GO:0043169	cation binding
1.66	1.45e-02	GO:0003682	chromatin binding
1.60	1.59e-02	GO:0003713	transcription coactivator activity
1.31	2.09e-02	GO:0016301	kinase activity
1.35	2.69e-02	GO:0004672	protein kinase activity
1.21	3.66e-02	GO:0032559	adenyl ribonucleotide binding
1.31	4.35e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.21	4.53e-02	GO:0030554	adenyl nucleotide binding
2.02	4.60e-02	GO:0042393	histone binding
2.46	4.79e-02	GO:0018024	histone-lysine N-methyltransferase activity