Motif ID: TBP.p2

Z-value: 2.104


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_1707053450.312.4e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_-_27139143 4.388 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_-_151052391 4.220 NM_005168
RND3
Rho family GTPase 3
chr21_-_27139563 4.181 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr4_-_75183700 3.379 CXCL2
chemokine (C-X-C motif) ligand 2
chr7_+_100557098 3.206 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr21_+_46342440 3.157 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr2_-_216009015 3.098 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr14_-_52487558 2.832 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr4_+_74953971 2.829 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr10_+_53744043 2.791 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr3_+_195336625 2.770 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr10_-_62373828 2.749 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr8_-_23317571 2.698 LOXL2
lysyl oxidase-like 2
chr17_+_29606408 2.698 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr17_-_45633986 2.690 NM_000088
COL1A1
collagen, type I, alpha 1
chr5_-_57791544 2.637 NM_006622
PLK2
polo-like kinase 2
chr17_-_45633873 2.567 COL1A1
collagen, type I, alpha 1
chr8_-_23077392 2.567 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr8_-_23317577 2.526 LOXL2
lysyl oxidase-like 2
chr16_+_55217180 2.476 MT1E
metallothionein 1E
chr12_+_12935759 2.458 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr8_-_23317536 2.429 LOXL2
lysyl oxidase-like 2
chr3_+_195336631 2.399 HES1
hairy and enhancer of split 1, (Drosophila)
chr16_+_55217085 2.363 NM_175617
MT1E
metallothionein 1E
chr20_-_43410437 2.346 NM_002999
SDC4
syndecan 4
chr15_+_78858763 2.322 NM_018689
KIAA1199
KIAA1199
chr14_+_74815233 2.257 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_-_179712920 2.201 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr15_+_37660568 2.199 NM_003246
THBS1
thrombospondin 1
chr10_-_92670764 2.138 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_+_17311282 2.082 VIM
vimentin
chr12_+_12935619 2.074 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_-_87498225 2.073 NM_000899
NM_003994
KITLG

KIT ligand

chr20_+_29656744 2.067 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr12_+_50686990 2.006 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr1_+_200775864 2.005 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr11_-_2907169 1.966 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr7_+_93862137 1.966 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr9_+_123088217 1.916 GSN
gelsolin
chr1_+_85819004 1.869 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr4_-_75123193 1.843 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr1_-_16355013 1.739 NM_004431
EPHA2
EPH receptor A2
chr9_-_116920232 1.734 NM_002160
TNC
tenascin C
chr10_+_17311283 1.734 VIM
vimentin
chr17_-_36469869 1.729 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr12_-_123568781 1.728


chr1_-_94779727 1.658 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr8_-_23317620 1.602 NM_002318
LOXL2
lysyl oxidase-like 2
chr1_-_8008934 1.541 ERRFI1
ERBB receptor feedback inhibitor 1
chr12_-_47869134 1.521 TUBA1A
tubulin, alpha 1a
chr17_-_68100537 1.517 LOC100499467
hypothetical LOC100499467
chr1_+_161305558 1.495 NM_001113381
RGS4
regulator of G-protein signaling 4
chr2_+_65517316 1.477 FLJ16124
FLJ16124 protein
chr4_-_75183860 1.428 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr8_-_48813256 1.424 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr17_+_76623540 1.407 NM_001144888
NM_006340
NM_017450
NM_017451
BAIAP2



BAI1-associated protein 2



chr6_-_169395847 1.398 THBS2
thrombospondin 2
chr5_+_15553288 1.373 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr8_-_134378630 1.370 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr9_+_91409746 1.339 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr15_-_58477407 1.338 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr19_+_18357966 1.326 NM_004864
GDF15
growth differentiation factor 15
chr17_+_76623553 1.289 BAIAP2
BAI1-associated protein 2
chr1_+_15957832 1.271 NM_017556
FBLIM1
filamin binding LIM protein 1
chr4_-_140317686 1.266 ELF2
E74-like factor 2 (ets domain transcription factor)
chr3_+_52504391 1.259 NM_015136
STAB1
stabilin 1
chr12_-_47869067 1.244 NM_006009
TUBA1A
tubulin, alpha 1a
chr1_-_85816520 1.211 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_3102690 1.208 NM_001069
TUBB2A
tubulin, beta 2A
chr1_-_199732323 1.195 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr17_+_30594192 1.175 NM_144975
SLFN5
schlafen family member 5
chr10_-_100017933 1.161 NM_032211
LOXL4
lysyl oxidase-like 4
chr10_+_17311307 1.152 VIM
vimentin
chr4_-_108176901 1.112 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr3_+_62279707 1.110 C3orf14
chromosome 3 open reading frame 14
chr8_-_124622434 1.109 NM_058229
FBXO32
F-box protein 32
chr1_-_151784889 1.106 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr19_+_627346 1.105 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr9_+_138677197 1.095 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr11_+_64946848 1.080


chr10_+_17311242 1.065 VIM
vimentin
chr13_+_30378311 1.062 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr17_-_71287417 1.046 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr17_-_30724732 1.034 NM_001104587
NM_001104588
NM_001104589
NM_001104590
NM_152270
SLFN11




schlafen family member 11




chr1_-_32940850 1.018 SYNC
syncoilin, intermediate filament protein
chr15_-_60244773 0.998 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr19_-_40939756 0.994 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr8_+_70567634 0.992 SULF1
sulfatase 1
chr6_-_74287483 0.970 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr8_-_143692814 0.966 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr6_+_132170847 0.966 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_-_35431329 0.965 NM_005066
SFPQ
splicing factor proline/glutamine-rich
chr15_+_30797466 0.963 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr11_+_64946820 0.962 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr3_-_130517759 0.961 NM_006026
H1FX
H1 histone family, member X
chr8_+_70541412 0.947 NM_001128204
NM_015170
SULF1

sulfatase 1

chr17_-_76622967 0.934 FLJ90757
hypothetical LOC440465
chr6_+_32021831 0.916 CFB
complement factor B
chr12_-_14929991 0.914 NM_000900
NM_001190839
MGP

matrix Gla protein

chr8_-_27528105 0.912 CLU
clusterin
chr16_+_55523526 0.899 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr1_-_35431318 0.894 SFPQ
splicing factor proline/glutamine-rich
chr3_+_149898347 0.891 NM_000685
NM_004835
NM_009585
NM_031850
AGTR1



angiotensin II receptor, type 1



chr6_-_74287453 0.886 NM_001402
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_1607580 0.883 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr11_-_2138984 0.877 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr1_-_154941861 0.875 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr11_-_8982107 0.866 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr22_-_34566276 0.856 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_-_45927263 0.855 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr15_-_61461127 0.847 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr7_-_41709191 0.820 NM_002192
INHBA
inhibin, beta A
chr6_-_134537699 0.810 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_44400952 0.804 NM_004123
GIP
gastric inhibitory polypeptide
chr2_-_179380301 0.796 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr15_-_53587723 0.796 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chrX_+_152699616 0.788 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr12_-_47868563 0.777 TUBA1A
tubulin, alpha 1a
chr5_-_42847716 0.768 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr2_-_238813365 0.762 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr15_-_32875040 0.757 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr5_+_53787187 0.756 NM_006308
HSPB3
heat shock 27kDa protein 3
chr7_-_128203079 0.747 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_+_33319287 0.747 NM_052998
ADC
arginine decarboxylase
chr1_+_78126787 0.747 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr1_+_148125090 0.744 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chrX_-_106846924 0.742 NM_004089
TSC22D3
TSC22 domain family, member 3
chr6_+_19945578 0.730 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr4_+_75529716 0.730 NM_001657
AREG
amphiregulin
chr19_+_46286207 0.720 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr12_-_55134692 0.719 NM_012064
MIP
major intrinsic protein of lens fiber
chr5_-_16795336 0.714 MYO10
myosin X
chr17_+_29621352 0.705 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr17_-_36436979 0.699 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr1_-_89129834 0.695 NM_001514
GTF2B
general transcription factor IIB
chr7_+_134114701 0.677 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr3_-_24511456 0.676 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr10_+_89409332 0.671 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr17_+_36493927 0.667 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr14_-_88087575 0.665 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr17_-_36451189 0.663 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr1_-_23758503 0.658 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr6_-_74287506 0.656 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr12_-_123965099 0.653 UBC
ubiquitin C
chr8_-_120033240 0.651 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr3_-_81893604 0.642 NM_000158
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr6_-_134540666 0.642 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr7_+_111908143 0.639 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr17_-_76064842 0.632 NM_002522
NPTX1
neuronal pentraxin I
chr1_+_161305188 0.632 NM_005613
RGS4
regulator of G-protein signaling 4
chr1_-_180627512 0.631 GLUL
glutamate-ammonia ligase
chr10_+_17311347 0.630 VIM
vimentin
chr1_-_226202210 0.630 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr17_-_53713265 0.626 NM_000250
MPO
myeloperoxidase
chr8_-_27528215 0.618 NM_001831
CLU
clusterin
chr6_-_52968035 0.611 NM_001512
GSTA4
glutathione S-transferase alpha 4
chr11_-_93774223 0.609 NM_016540
GPR83
G protein-coupled receptor 83
chr2_-_162717159 0.605 NM_002054
GCG
glucagon
chr17_-_10217046 0.603 NM_003802
MYH13
myosin, heavy chain 13, skeletal muscle
chr17_-_36807322 0.602 NM_002277
KRT31
keratin 31
chr1_-_89129769 0.602 GTF2B
general transcription factor IIB
chr7_+_44802798 0.595 PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr17_-_59342319 0.592 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr8_+_23016271 0.587 NM_003841
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr15_+_61121806 0.586 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr6_-_26125939 0.582 NM_005325
HIST1H1A
histone cluster 1, H1a
chr3_-_81893506 0.580 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr7_+_44802834 0.575 PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr11_+_2355099 0.569 CD81
CD81 molecule
chr15_-_61460967 0.566 CA12
carbonic anhydrase XII
chr2_+_33514896 0.563 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_+_50913274 0.560 KRT7
keratin 7
chr20_-_38751289 0.560 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr7_+_44802691 0.559 NM_021130
PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr19_+_16296734 0.552 KLF2
Kruppel-like factor 2 (lung)
chr12_+_79634820 0.551 NM_005593
MYF5
myogenic factor 5
chr11_-_62213577 0.551 LRRN4CL
LRRN4 C-terminal like
chr21_+_18539016 0.551 NM_024944
CHODL
chondrolectin
chrX_-_106846684 0.548 TSC22D3
TSC22 domain family, member 3
chr8_-_48813236 0.545 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr17_-_36792161 0.545 NM_021013
KRT34
keratin 34
chr11_+_43920385 0.538 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr7_-_6490375 0.537 KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr1_-_228916486 0.535 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr10_-_3817418 0.514 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr1_-_228916470 0.511 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr2_-_216944911 0.507 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr3_-_81893492 0.504 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr7_+_30917939 0.504 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr1_-_148124738 0.502 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr11_+_1064869 0.500 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr16_+_84202515 0.499 NM_001134473
KIAA0182
KIAA0182
chr1_-_8008979 0.497 NM_018948
ERRFI1
ERBB receptor feedback inhibitor 1
chr16_+_76613912 0.493 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr11_-_102156531 0.491 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr5_+_78443357 0.482 NM_001713
BHMT
betaine--homocysteine S-methyltransferase
chr9_+_130354490 0.479 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr20_+_31287462 0.479 NM_016583
NM_130852
PLUNC

palate, lung and nasal epithelium associated

chr17_-_10362583 0.479 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr5_+_176744037 0.478 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.87 2.42e-08 GO:0042221 response to chemical stimulus
1.45 8.65e-07 GO:0032501 multicellular organismal process
1.75 1.47e-06 GO:0006950 response to stress
2.32 1.37e-05 GO:0009888 tissue development
8.92 3.96e-05 GO:0034614 cellular response to reactive oxygen species
1.79 4.49e-05 GO:0048513 organ development
1.59 1.04e-04 GO:0048731 system development
1.54 2.18e-04 GO:0048856 anatomical structure development
2.14 2.19e-04 GO:0070887 cellular response to chemical stimulus
6.81 2.34e-04 GO:0034599 cellular response to oxidative stress
3.29 3.08e-04 GO:0010035 response to inorganic substance
1.91 5.67e-04 GO:0010033 response to organic substance
4.43 1.04e-03 GO:0051789 response to protein stimulus
1.31 1.19e-03 GO:0050896 response to stimulus
1.44 1.31e-03 GO:0032502 developmental process
9.73 1.66e-03 GO:0070301 cellular response to hydrogen peroxide
2.05 2.40e-03 GO:0009611 response to wounding
2.53 2.46e-03 GO:0072358 cardiovascular system development
2.53 2.46e-03 GO:0072359 circulatory system development
1.62 2.67e-03 GO:0065008 regulation of biological quality
4.98 3.17e-03 GO:0000302 response to reactive oxygen species
2.28 4.45e-03 GO:0009725 response to hormone stimulus
2.26 7.20e-03 GO:0009887 organ morphogenesis
4.61 7.55e-03 GO:0009266 response to temperature stimulus
1.73 8.75e-03 GO:0009653 anatomical structure morphogenesis
1.43 8.88e-03 GO:0007275 multicellular organismal development
2.02 1.22e-02 GO:0006952 defense response
2.42 1.25e-02 GO:0048646 anatomical structure formation involved in morphogenesis
2.13 1.53e-02 GO:0009719 response to endogenous stimulus
1.77 1.72e-02 GO:0051239 regulation of multicellular organismal process
3.23 2.13e-02 GO:0008544 epidermis development
2.80 2.39e-02 GO:0001944 vasculature development
5.32 2.70e-02 GO:0006986 response to unfolded protein
4.40 2.92e-02 GO:0006334 nucleosome assembly
1.91 3.20e-02 GO:0050793 regulation of developmental process
4.30 3.63e-02 GO:0030198 extracellular matrix organization
9.73 4.03e-02 GO:0030239 myofibril assembly
5.68 4.24e-02 GO:0051591 response to cAMP
4.17 4.99e-02 GO:0031497 chromatin assembly

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
8.97 1.72e-27 GO:0005882 intermediate filament
7.76 1.25e-24 GO:0045111 intermediate filament cytoskeleton
3.28 4.70e-23 GO:0044421 extracellular region part
3.66 1.28e-22 GO:0005615 extracellular space
2.40 2.91e-21 GO:0005576 extracellular region
11.07 2.61e-18 GO:0045095 keratin filament
2.37 2.03e-09 GO:0044430 cytoskeletal part
2.07 5.22e-09 GO:0005856 cytoskeleton
1.59 1.55e-05 GO:0043228 non-membrane-bounded organelle
1.59 1.55e-05 GO:0043232 intracellular non-membrane-bounded organelle
2.83 6.43e-05 GO:0031012 extracellular matrix
6.04 3.55e-04 GO:0000786 nucleosome
4.15 6.82e-04 GO:0043292 contractile fiber
4.22 1.21e-03 GO:0044449 contractile fiber part
4.11 1.64e-03 GO:0030016 myofibril
11.35 1.90e-03 GO:0032982 myosin filament
2.68 2.55e-03 GO:0005578 proteinaceous extracellular matrix
5.90 3.95e-03 GO:0031983 vesicle lumen
5.68 1.54e-02 GO:0031674 I band
5.68 1.54e-02 GO:0034774 secretory granule lumen
5.45 2.09e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.86 2.78e-02 GO:0032993 protein-DNA complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.05 1.88e-10 GO:0005198 structural molecule activity
2.31 6.09e-08 GO:0005102 receptor binding
5.85 1.32e-06 GO:0005179 hormone activity
3.77 3.17e-05 GO:0005125 cytokine activity
3.64 1.47e-03 GO:0008083 growth factor activity
1.23 1.91e-03 GO:0005515 protein binding
3.31 2.92e-03 GO:0005126 cytokine receptor binding
3.41 6.56e-03 GO:0001871 pattern binding
3.41 6.56e-03 GO:0030247 polysaccharide binding
4.68 7.07e-03 GO:0005201 extracellular matrix structural constituent
3.95 8.24e-03 GO:0008201 heparin binding
3.45 1.02e-02 GO:0005539 glycosaminoglycan binding
6.34 1.04e-02 GO:0008307 structural constituent of muscle
2.41 1.13e-02 GO:0030246 carbohydrate binding
4.80 1.36e-02 GO:0005200 structural constituent of cytoskeleton
5.92 1.74e-02 GO:0008009 chemokine activity
5.34 3.74e-02 GO:0042379 chemokine receptor binding
6.11 4.21e-02 GO:0005518 collagen binding
3.38 4.27e-02 GO:0046906 tetrapyrrole binding
5.24 4.30e-02 GO:0005507 copper ion binding