Motif ID: ATF6.p2

Z-value: 2.262


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_160002746-0.581.9e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_20533629 3.224 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr19_+_54723044 3.139 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr3_-_73756668 3.005 NM_015009
 PDZRN3
PDZ domain containing ring finger 3
chr14_+_100362204 2.819 MEG3
maternally expressed 3 (non-protein coding)
chr7_+_27191534 2.703 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr4_-_186693574 2.695 NM_001114107
NM_014476
 PDLIM3

PDZ and LIM domain 3

chrX_+_100692071 2.619 NM_016608
 ARMCX1
armadillo repeat containing, X-linked 1
chr4_-_187884721 2.533


chr13_-_35818777 2.439 NM_001142295
 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr2_+_28469199 2.432 FOSL2
FOS-like antigen 2
chr2_+_28469275 2.429 NM_005253
 FOSL2
FOS-like antigen 2
chr4_-_24523605 2.324 NM_001130726
 CCDC149
coiled-coil domain containing 149
chr12_-_123568781 2.318


chr2_+_28469172 2.295 FOSL2
FOS-like antigen 2
chr17_-_13445942 2.280 NM_006042
 HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr7_+_93861808 2.227 NM_000089
 COL1A2
collagen, type I, alpha 2
chr14_+_100362236 2.216 MEG3
maternally expressed 3 (non-protein coding)
chr13_-_35818603 2.172 NM_001142296
NM_015087
 SPG20

spastic paraplegia 20 (Troyer syndrome)

chr14_+_22375632 2.097 NM_004995
 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr8_+_106400322 2.081 NM_012082
 ZFPM2
zinc finger protein, multitype 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 56 entries
enrichment   p-value GO term description
8.68 1.58e-05 GO:0048199 vesicle targeting, to, from or within Golgi
6.31 2.99e-04 GO:0006903 vesicle targeting
5.92 2.19e-02 GO:0006901 vesicle coating
5.68 3.23e-02 GO:0006900 membrane budding
5.26 3.93e-04 GO:0051650 establishment of vesicle localization
4.17 9.23e-03 GO:0051648 vesicle localization
3.42 8.92e-03 GO:0043392 negative regulation of DNA binding
2.99 1.89e-03 GO:0048193 Golgi vesicle transport
2.63 4.73e-02 GO:0006184 GTP catabolic process
2.20 2.45e-02 GO:0051101 regulation of DNA binding
2.07 1.01e-04 GO:0034613 cellular protein localization
2.06 1.28e-04 GO:0070727 cellular macromolecule localization
1.99 1.62e-02 GO:0006886 intracellular protein transport
1.98 1.90e-07 GO:0015031 protein transport
1.96 2.33e-07 GO:0045184 establishment of protein localization
1.92 9.62e-09 GO:0008104 protein localization
1.86 1.24e-05 GO:0006351 transcription, DNA-dependent
1.81 1.78e-08 GO:0033036 macromolecule localization
1.81 3.07e-04 GO:0046907 intracellular transport
1.76 2.91e-03 GO:0016192 vesicle-mediated transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
7.89 3.62e-03 GO:0030663 COPI coated vesicle membrane
6.50 1.73e-02 GO:0030137 COPI-coated vesicle
4.05 4.61e-02 GO:0030120 vesicle coat
3.57 3.69e-02 GO:0005793 ER-Golgi intermediate compartment
3.01 1.50e-02 GO:0042470 melanosome
3.01 1.50e-02 GO:0048770 pigment granule
2.14 4.70e-06 GO:0000139 Golgi membrane
1.98 1.29e-05 GO:0044431 Golgi apparatus part
1.72 2.42e-05 GO:0005794 Golgi apparatus
1.62 9.40e-03 GO:0031410 cytoplasmic vesicle
1.61 9.04e-03 GO:0031982 vesicle
1.55 2.73e-03 GO:0005783 endoplasmic reticulum
1.54 3.82e-05 GO:0012505 endomembrane system
1.48 6.41e-06 GO:0031090 organelle membrane
1.34 1.33e-02 GO:0044428 nuclear part
1.29 5.37e-08 GO:0044422 organelle part
1.29 1.20e-07 GO:0044446 intracellular organelle part
1.27 8.03e-07 GO:0005634 nucleus
1.26 1.40e-14 GO:0043227 membrane-bounded organelle
1.26 1.77e-14 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.80 3.59e-04 GO:0043565 sequence-specific DNA binding
1.79 1.79e-06 GO:0001071 nucleic acid binding transcription factor activity
1.79 1.79e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.77 2.56e-06 GO:0030528 transcription regulator activity
1.35 5.11e-03 GO:0003677 DNA binding
1.23 1.21e-07 GO:0005515 protein binding
1.10 4.52e-04 GO:0005488 binding