Motif ID: AIRE.p2

Z-value: 1.088


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
AIREchr21_+_44530148-0.224.1e-01Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_75734759 2.188 NM_006633
 IQGAP2
IQ motif containing GTPase activating protein 2
chr13_-_40454188 1.759 ELF1
E74-like factor 1 (ets domain transcription factor)
chr19_+_55627971 1.494 NM_004533
 MYBPC2
myosin binding protein C, fast type
chr11_-_73371531 1.479 NM_003355
 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_-_59437782 1.451 NM_000873
 ICAM2
intercellular adhesion molecule 2
chr4_-_139382672 1.243 NM_014331
 SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr13_-_40454360 1.224 NM_001145353
 ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_+_69716298 1.221 NM_001075
NM_001144767
 UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr16_+_20328355 1.195 NM_017888
 ACSM5
acyl-CoA synthetase medium-chain family member 5
chr17_+_38259620 1.111 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr8_-_41774296 1.039 NM_000037
NM_020475
NM_020476
NM_020477
 ANK1



ankyrin 1, erythrocytic



chr7_+_116238309 1.023 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chrX_-_2892288 0.978 NM_000047
 ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr19_+_18069596 0.928 NM_015016
 MAST3
microtubule associated serine/threonine kinase 3
chr4_-_123761615 0.928 NM_021803
 IL21
interleukin 21
chr8_-_30704984 0.872 NM_000637
NM_001195102
NM_001195103
NM_001195104
 GSR



glutathione reductase



chr19_-_44518516 0.821 NM_004877
 GMFG
glia maturation factor, gamma
chr6_+_31791063 0.793 NM_021246
 LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr11_-_62195587 0.785 C11orf48
chromosome 11 open reading frame 48
chr19_-_6621078 0.761 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.03 1.75e-02 GO:0002682 regulation of immune system process
1.72 2.98e-02 GO:0002376 immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.