Motif ID: CDC5L.p2

Z-value: 1.132


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_444634180.495.4e-02Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_13992351 2.015 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr6_-_49712483 1.633 NM_000324
RHAG
Rh-associated glycoprotein
chr2_-_160764819 1.594 NM_000888
ITGB6
integrin, beta 6
chr10_+_111755715 1.526 NM_019903
ADD3
adducin 3 (gamma)
chr6_+_132000134 1.507 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr5_-_138238891 1.312 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr10_-_69267774 1.198 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr5_-_138238877 1.195 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr12_+_18305740 1.053 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr2_-_160765008 1.012 ITGB6
integrin, beta 6
chr5_-_138238953 0.997 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr3_-_110155237 0.963 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr6_+_105511615 0.957 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chrX_-_15593074 0.900 NM_020665
TMEM27
transmembrane protein 27
chr4_-_40211324 0.899 RBM47
RNA binding motif protein 47
chr4_+_128773529 0.889 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr8_-_102029997 0.869 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr19_+_16691786 0.832 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr11_+_27019084 0.803 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_556968 0.798


chr1_+_557269 0.794


chr12_-_78831821 0.782 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr2_-_162808123 0.705 NM_004460
FAP
fibroblast activation protein, alpha
chr10_+_49279647 0.692 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr12_+_56802 0.690 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr9_+_74956494 0.684 NM_000700
ANXA1
annexin A1
chr9_+_74956601 0.674 ANXA1
annexin A1
chr8_+_75899326 0.671 NM_015886
PI15
peptidase inhibitor 15
chr1_-_20682541 0.671


chr9_+_74956614 0.670 ANXA1
annexin A1
chr3_-_139315011 0.657 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr14_+_38772870 0.644 NM_054024
MIA2
melanoma inhibitory activity 2
chr19_+_1223475 0.640 CIRBP
cold inducible RNA binding protein
chr16_-_45562840 0.634 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr12_+_16391795 0.627 NM_020300
NM_145791
MGST1

microsomal glutathione S-transferase 1

chr6_-_116973465 0.626 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr8_+_22266256 0.625 PIWIL2
piwi-like 2 (Drosophila)
chr3_-_95230143 0.621 NM_001001850
STX19
syntaxin 19
chr2_+_165804157 0.598 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr14_-_80934523 0.595 NM_033104
STON2
stonin 2
chr7_-_16471817 0.594 NM_015464
SOSTDC1
sclerostin domain containing 1
chrX_-_106336199 0.585 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr1_+_43063817 0.584 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr13_-_85271329 0.582 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr5_-_134291882 0.578


chr4_-_15549047 0.576 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr1_+_25471470 0.568 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr3_-_156876798 0.560 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr1_+_89602023 0.556 NM_198460
GBP6
guanylate binding protein family, member 6
chr6_-_112001590 0.540 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr5_-_125956996 0.539 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr11_+_5466490 0.514 NM_001005163
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr10_-_105835609 0.514 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr4_+_95595419 0.508 PDLIM5
PDZ and LIM domain 5
chr1_-_25619863 0.494 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chr3_-_152517204 0.491 NM_023915
GPR87
G protein-coupled receptor 87
chr18_+_54039818 0.489 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr7_-_26202626 0.483 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_+_145297490 0.479 SH3RF2
SH3 domain containing ring finger 2
chr2_-_73781974 0.467 NM_016347
NAT8B
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
chr3_-_9266251 0.451 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr12_-_52939636 0.449 NM_001127321
CBX5
chromobox homolog 5
chr22_-_37044034 0.439 NM_001894
CSNK1E
casein kinase 1, epsilon
chr2_-_225078931 0.436 CUL3
cullin 3
chr12_-_52939584 0.429 NM_001127322
CBX5
chromobox homolog 5
chr6_-_119137923 0.428 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr6_+_64414389 0.426 NM_015153
PHF3
PHD finger protein 3
chr1_-_180624380 0.424 GLUL
glutamate-ammonia ligase
chr3_-_188946168 0.419 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr19_-_10558906 0.410 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_-_120112989 0.408 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr11_-_106833715 0.406 NM_152434
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr5_-_132228375 0.404 NM_005260
GDF9
growth differentiation factor 9
chr18_-_53438854 0.404


chr12_-_51114372 0.403 NM_004693
KRT75
keratin 75
chr20_-_33706532 0.400 RBM12
RNA binding motif protein 12
chr5_-_98290117 0.400 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr21_+_38550533 0.399 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_151270301 0.398 NM_003125
SPRR1B
small proline-rich protein 1B
chr13_+_51496679 0.391 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr11_-_100505667 0.391 NM_000926
PGR
progesterone receptor
chr1_-_180624494 0.391 GLUL
glutamate-ammonia ligase
chrX_-_19598912 0.387 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr3_+_123526700 0.386 NM_005213
CSTA
cystatin A (stefin A)
chr2_+_183316574 0.376 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr1_+_234624266 0.376 NM_145861
EDARADD
EDAR-associated death domain
chr12_-_21818881 0.371 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr1_+_239762179 0.370 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr14_-_49543987 0.369 NM_001012706
C14orf182
chromosome 14 open reading frame 182
chr21_-_31012965 0.368 NM_001164435
KRTAP21-3
keratin associated protein 21-3
chrX_-_15312390 0.363 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr11_+_111551417 0.361 NM_031938
BCO2
beta-carotene oxygenase 2
chr1_-_93030538 0.351 NM_005665
EVI5
ecotropic viral integration site 5
chr20_-_33705244 0.350 NM_003915
CPNE1
copine I
chrX_+_65300803 0.346 NM_001130860
NM_014799
HEPH

hephaestin

chrX_-_23955223 0.344 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr12_-_52975823 0.340 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr4_+_130236731 0.339 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr2_-_61098867 0.338 NM_144709
PUS10
pseudouridylate synthase 10
chr4_-_90197140 0.333 NM_014883
FAM13A
family with sequence similarity 13, member A
chr3_+_142175329 0.329 SLC25A36
solute carrier family 25, member 36
chr1_-_203592538 0.327 NM_018203
KLHDC8A
kelch domain containing 8A
chr1_+_66230977 0.311 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_-_62764839 0.305 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr11_-_83706027 0.303 DLG2
discs, large homolog 2 (Drosophila)
chr6_+_57290357 0.301 NM_000947
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr7_+_110518297 0.301 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr6_+_147568795 0.301 STXBP5
syntaxin binding protein 5 (tomosyn)
chr7_+_123083096 0.300 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr16_+_68238460 0.295 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr4_-_77176163 0.295 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr10_-_23673777 0.295 NM_153714
C10orf67
chromosome 10 open reading frame 67
chr11_+_85036610 0.291 NM_032273
TMEM126A
transmembrane protein 126A
chr1_+_40977092 0.291 NFYC
nuclear transcription factor Y, gamma
chr11_-_6148131 0.290 NM_001004052
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chr22_-_34564611 0.290 RPL41P5
ribosomal protein L41 pseudogene 5
chr6_-_136888771 0.289 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr7_-_13996166 0.288 NM_001163147
NM_004956
ETV1

ets variant 1

chr4_+_109763119 0.287 RPL34
ribosomal protein L34
chr2_+_183697327 0.287 NM_138285
NUP35
nucleoporin 35kDa
chr1_-_196776697 0.287 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr18_+_59593591 0.282 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr10_-_116276560 0.280 ABLIM1
actin binding LIM protein 1
chr2_+_66516196 0.280 MEIS1
Meis homeobox 1
chr10_-_93992982 0.280 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr17_-_57023322 0.278 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr4_-_145159889 0.278 NM_002100
GYPB
glycophorin B (MNS blood group)
chr9_+_134843918 0.278 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr12_+_77963563 0.276 NM_001135806
SYT1
synaptotagmin I
chr12_+_53534565 0.275 NM_058173
MUCL1
mucin-like 1
chr1_-_152431175 0.275 NM_152263
TPM3
tropomyosin 3
chr1_-_143708467 0.272 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr10_-_62163083 0.272 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_-_52975777 0.269 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr6_-_50025115 0.269 NM_001166478
DEFB133
defensin, beta 133
chr6_-_90081655 0.269 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr4_+_109033868 0.268 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr13_-_40491405 0.268 ELF1
E74-like factor 1 (ets domain transcription factor)
chr12_-_44877769 0.267 SLC38A1
solute carrier family 38, member 1
chr6_-_10939095 0.267 NM_005906
MAK
male germ cell-associated kinase
chr15_-_74963246 0.265 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr8_-_145672525 0.264 NM_003923
FOXH1
forkhead box H1
chr9_+_12764988 0.263 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr19_-_21438525 0.263


chr13_-_40491491 0.263 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr10_-_94247450 0.261 NM_001165946
IDE
insulin-degrading enzyme
chrX_+_77052834 0.260 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_162717159 0.259 NM_002054
GCG
glucagon
chr21_-_35174742 0.256 RUNX1
runt-related transcription factor 1
chr11_-_13474101 0.256 NM_000315
PTH
parathyroid hormone
chr3_+_187840842 0.255 NM_014375
FETUB
fetuin B
chr2_+_73973640 0.253 ACTG2
actin, gamma 2, smooth muscle, enteric
chr17_+_70540265 0.249 KCTD2
potassium channel tetramerisation domain containing 2
chr17_-_7434113 0.248 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr4_+_106851415 0.247 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr14_+_19365447 0.245 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr6_+_29902734 0.243 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr12_+_8866416 0.242 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr15_-_41195994 0.239 RPS3A
ribosomal protein S3A
chr11_-_117640166 0.238 MPZL2
myelin protein zero-like 2
chr22_-_34566367 0.236 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr9_+_35663852 0.235 NM_001216
CA9
carbonic anhydrase IX
chr17_-_64462976 0.234 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr4_-_74307637 0.234 ANKRD17
ankyrin repeat domain 17
chr10_+_5126589 0.234 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr11_+_59580705 0.232 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr10_+_5126556 0.231 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr11_-_117640078 0.229


chr4_+_74825138 0.228 NM_000584
IL8
interleukin 8
chr20_+_31613800 0.227 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr12_-_101036407 0.225 NM_024057
NUP37
nucleoporin 37kDa
chr3_+_153468518 0.224 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr8_-_133186693 0.223 NM_001145095
HHLA1
HERV-H LTR-associating 1
chrX_+_110252960 0.222 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr1_-_51660328 0.221 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr11_-_5178505 0.221 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr12_-_15706340 0.220 EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_156716290 0.217 NM_001004472
OR10R2
olfactory receptor, family 10, subfamily R, member 2
chr11_+_55407348 0.217 NM_032681
SPRYD5
SPRY domain containing 5
chr4_-_70760381 0.216 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr1_+_114295289 0.216 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr14_-_57133361 0.215 NM_001080455
SLC35F4
solute carrier family 35, member F4
chr10_-_21226536 0.215 NM_006393
NEBL
nebulette
chr15_+_70193652 0.211 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chr14_-_20128228 0.211 NM_145250
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr4_+_53986759 0.211 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr4_-_54152480 0.210 NM_001126328
LNX1
ligand of numb-protein X 1
chr3_+_153499883 0.210 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr4_-_186969041 0.210 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chrX_+_100111352 0.209 NM_001012990
NM_001162490
NM_001162491
ARL13A


ADP-ribosylation factor-like 13A


chr10_+_5126613 0.209 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr11_+_59580630 0.209 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr4_-_68793928 0.208 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr1_+_23890857 0.207 RPL11
ribosomal protein L11
chr1_+_40612891 0.206 NM_001198978
SMAP2
small ArfGAP2
chr2_+_165858586 0.205 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_+_54011750 0.204 NM_054104
OR6C3
olfactory receptor, family 6, subfamily C, member 3
chrX_-_118610880 0.204 NM_001173488
NKRF
NFKB repressing factor
chr1_-_159543847 0.204 MPZ
myelin protein zero
chr11_+_111552298 0.203 NM_001037290
BCO2
beta-carotene oxygenase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.48 2.10e-04 GO:0007608 sensory perception of smell
2.33 5.68e-04 GO:0007606 sensory perception of chemical stimulus
1.89 3.68e-03 GO:0007600 sensory perception
1.54 1.92e-02 GO:0003008 system process
1.26 2.35e-02 GO:0032501 multicellular organismal process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.47 1.25e-04 GO:0004984 olfactory receptor activity
3.58 2.74e-02 GO:0004867 serine-type endopeptidase inhibitor activity