Motif ID: HES1.p2

Z-value: 1.316


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HES1chr3_+_195336631-0.611.3e-02Click!


Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_77094426 1.695 ACTG1
actin, gamma 1
chr5_+_75734759 1.612 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr19_-_50963942 1.556


chr9_-_125070613 1.474 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr20_-_62081434 1.421 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr19_+_34994701 1.394 NM_001238
CCNE1
cyclin E1
chr21_-_45786709 1.394 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr22_-_27405708 1.352 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr8_-_12657339 1.287 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr17_-_77094375 1.202 NM_001614
ACTG1
actin, gamma 1
chr20_-_62151216 1.159 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr15_+_39573363 1.067 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr1_-_45444812 1.060 NM_020883
ZSWIM5
zinc finger, SWIM-type containing 5
chr17_+_37941476 1.059 NM_000263
NAGLU
N-acetylglucosaminidase, alpha
chr18_+_2836979 1.040 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr17_-_3814334 1.039 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr16_-_87244896 0.997 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr9_-_125070675 0.984 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr3_+_129690735 0.970


chr19_+_2240996 0.905


chr22_-_49311439 0.888 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr7_+_149651481 0.887 LRRC61
leucine rich repeat containing 61
chr7_-_149651594 0.886 NM_001164458
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr7_+_149651202 0.884 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr7_-_23476156 0.875


chr1_+_9522107 0.869 NM_032315
SLC25A33
solute carrier family 25, member 33
chr22_+_40559070 0.869 SREBF2
sterol regulatory element binding transcription factor 2
chr3_-_127558747 0.862 NM_014079
KLF15
Kruppel-like factor 15
chr4_+_57469122 0.843 REST
RE1-silencing transcription factor
chr20_-_62081752 0.843 SAMD10
sterile alpha motif domain containing 10
chr1_+_226937732 0.833 RHOU
ras homolog gene family, member U
chr1_+_9522133 0.830 SLC25A33
solute carrier family 25, member 33
chr17_-_39757660 0.830 SLC25A39
solute carrier family 25, member 39
chr20_+_55399847 0.824 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr22_+_18091065 0.802 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr1_-_92124064 0.799 TGFBR3
transforming growth factor, beta receptor III
chr11_-_67153959 0.788 NM_181843
NUDT8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr6_+_111515341 0.783 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr19_-_1352474 0.781 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr20_-_61728866 0.781 GMEB2
glucocorticoid modulatory element binding protein 2
chr6_+_157722467 0.778 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr22_+_40559214 0.775 SREBF2
sterol regulatory element binding transcription factor 2
chr22_+_40559051 0.766 NM_004599
SREBF2
sterol regulatory element binding transcription factor 2
chr3_-_13436802 0.759 NM_024923
NUP210
nucleoporin 210kDa
chr16_+_65870641 0.758 PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr19_+_18391423 0.749


chr3_-_13436725 0.748 NUP210
nucleoporin 210kDa
chr12_+_6893751 0.747 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr10_+_92912676 0.744 PCGF5
polycomb group ring finger 5
chr17_+_37941790 0.736 NAGLU
N-acetylglucosaminidase, alpha
chr5_-_1547872 0.725 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr9_+_130491340 0.720 SET
SET nuclear oncogene
chr17_+_37941715 0.719 NAGLU
N-acetylglucosaminidase, alpha
chr18_+_586997 0.715 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr17_-_73636386 0.713 NM_001127198
TMC6
transmembrane channel-like 6
chr20_-_49592654 0.711 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr5_-_132194488 0.706 NM_001172700
SHROOM1
shroom family member 1
chr22_+_40559083 0.705 SREBF2
sterol regulatory element binding transcription factor 2
chr16_+_387176 0.696 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr17_-_73636362 0.687 TMC6
transmembrane channel-like 6
chr16_+_66153810 0.683 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr7_+_149696263 0.680 REPIN1
replication initiator 1
chr20_-_34635091 0.680


chr16_+_29725311 0.676 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr19_+_868285 0.675 NM_032551
KISS1R
KISS1 receptor
chr17_+_63799228 0.671 ARSG
arylsulfatase G
chr11_+_65414677 0.658 CCDC85B
coiled-coil domain containing 85B
chr6_-_43305156 0.654 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr22_-_17545872 0.651 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_+_10101081 0.645 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr19_-_8279157 0.645 NM_001165895
NM_016579
CD320

CD320 molecule

chr3_+_154035425 0.643 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr19_-_10474767 0.640 NM_203500
KEAP1
kelch-like ECH-associated protein 1
chr20_+_254205 0.639 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr17_-_77422526 0.638 ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr9_-_139316523 0.635 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr7_+_149696792 0.629 NM_001099695
NM_001099696
NM_013400
REPIN1


replication initiator 1


chr22_-_49311722 0.629 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr21_+_44109454 0.628 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_-_10475083 0.628 KEAP1
kelch-like ECH-associated protein 1
chr16_-_1369613 0.626 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr21_-_43368963 0.617 NM_000071
CBS
cystathionine-beta-synthase
chr9_-_85761451 0.612 C9orf64
chromosome 9 open reading frame 64
chr1_-_53566171 0.610 NM_001018054
NM_004631
NM_017522
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr10_-_95350949 0.600 NM_006744
RBP4
retinol binding protein 4, plasma
chr4_+_57468847 0.593 REST
RE1-silencing transcription factor
chr2_+_128175413 0.590 SFT2D3
SFT2 domain containing 3
chr1_+_165865953 0.584 NM_052862
RCSD1
RCSD domain containing 1
chr9_-_85761472 0.580 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr2_-_10506033 0.579 ODC1
ornithine decarboxylase 1
chr1_-_53566331 0.577 NM_033300
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_-_11042668 0.576 NM_003132
SRM
spermidine synthase
chr6_+_57145292 0.576 BAG2
BCL2-associated athanogene 2
chr20_+_34635362 0.575 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr17_+_43081837 0.571 KPNB1
karyopherin (importin) beta 1
chr10_-_60606195 0.571


chr20_-_61728774 0.570 NM_012384
GMEB2
glucocorticoid modulatory element binding protein 2
chr1_-_210939727 0.568


chr6_+_34312906 0.565 HMGA1
high mobility group AT-hook 1
chr1_+_36046373 0.564 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr20_-_31737731 0.564 E2F1
E2F transcription factor 1
chr9_-_139084833 0.563 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr1_-_41480379 0.562 NM_001172218
NM_001172219
NM_001172220
NM_012236
SCMH1



sex comb on midleg homolog 1 (Drosophila)



chr4_+_1842833 0.559 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr20_+_34667624 0.555 C20orf24
chromosome 20 open reading frame 24
chr19_+_3310138 0.555 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr9_+_130491370 0.547 SET
SET nuclear oncogene
chr3_-_129690056 0.546 NM_001145661
GATA2
GATA binding protein 2
chr15_+_48261649 0.542 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr2_-_96351345 0.539


chr19_+_1055614 0.539 NM_001039848
GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr7_-_65084668 0.539 NM_000181
GUSB
glucuronidase, beta
chr2_+_10101822 0.536 NM_001177718
KLF11
Kruppel-like factor 11
chr2_+_242289983 0.535 NM_032329
ING5
inhibitor of growth family, member 5
chr19_-_2002222 0.534 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr6_-_35216981 0.532 NM_001093728
NM_018679
TCP11

t-complex 11 homolog (mouse)

chr22_+_40559053 0.528 SREBF2
sterol regulatory element binding transcription factor 2
chr6_+_34312667 0.528 HMGA1
high mobility group AT-hook 1
chr16_-_2330594 0.527 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr20_-_3102169 0.525 ProSAPiP1
ProSAPiP1 protein
chr6_-_125664913 0.524 NM_016063
HDDC2
HD domain containing 2
chr15_-_29950188 0.523 OTUD7A
OTU domain containing 7A
chr7_-_103417198 0.523 NM_005045
NM_173054
RELN

reelin

chr4_+_57468792 0.520 NM_005612
REST
RE1-silencing transcription factor
chr2_+_170298700 0.520 KLHL23
kelch-like 23 (Drosophila)
chr7_+_149696901 0.520 REPIN1
replication initiator 1
chr1_-_218168548 0.519 NM_018713
SLC30A10
solute carrier family 30, member 10
chr1_-_41480368 0.519 SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr4_-_1232882 0.518 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1

chr17_-_77488258 0.517 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr3_+_128830656 0.516 NM_015720
PODXL2
podocalyxin-like 2
chr11_+_43920385 0.513 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr9_+_130491291 0.512 NM_003011
SET
SET nuclear oncogene
chr16_+_517834 0.511 NM_005632
SOLH
small optic lobes homolog (Drosophila)
chr7_-_148212336 0.511 NM_004456
NM_152998
EZH2

enhancer of zeste homolog 2 (Drosophila)

chr2_+_203207912 0.510 FAM117B
family with sequence similarity 117, member B
chr9_-_138880530 0.508 NM_003792
NM_153200
EDF1

endothelial differentiation-related factor 1

chr5_+_133478252 0.507 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr16_+_65870481 0.506 NM_001129728
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr22_+_18484810 0.506 NM_002882
RANBP1
RAN binding protein 1
chr4_-_2233606 0.506 MXD4
MAX dimerization protein 4
chr21_+_44109529 0.505 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr18_-_11138760 0.504 NM_022068
FAM38B
family with sequence similarity 38, member B
chr22_-_37481857 0.503 NM_015374
SUN2
Sad1 and UNC84 domain containing 2
chr1_+_53698070 0.501 DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr17_+_75366524 0.500 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr11_+_279113 0.500 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr7_+_93977267 0.499 CASD1
CAS1 domain containing 1
chr1_-_32574185 0.496 NM_023009
MARCKSL1
MARCKS-like 1
chr11_-_67645246 0.496 CHKA
choline kinase alpha
chr19_+_10402334 0.494 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_+_935316 0.492 NM_024100
WDR18
WD repeat domain 18
chr9_-_125732005 0.490 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr16_+_1979959 0.489 NM_004209
SYNGR3
synaptogyrin 3
chr17_+_43374021 0.487 PNPO
pyridoxamine 5'-phosphate oxidase
chr22_-_37481925 0.482 SUN2
Sad1 and UNC84 domain containing 2
chr17_+_50698169 0.480 HLF
hepatic leukemia factor
chr7_-_150408785 0.478 FASTK
Fas-activated serine/threonine kinase
chr7_-_960897 0.477 ADAP1
ArfGAP with dual PH domains 1
chr1_-_1700088 0.477 NM_001198993
NADK
NAD kinase
chr10_+_92970302 0.476 NM_032373
PCGF5
polycomb group ring finger 5
chr1_+_153317887 0.475 NM_004952
EFNA3
ephrin-A3
chrX_-_18282698 0.473 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr20_+_48032918 0.473 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr19_-_10474266 0.472 NM_012289
KEAP1
kelch-like ECH-associated protein 1
chr7_-_148212310 0.471 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_+_99865189 0.467 NM_019606
MEPCE
methylphosphate capping enzyme
chr22_-_18807805 0.467 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr16_-_87300233 0.466 NM_001171815
RNF166
ring finger protein 166
chr7_-_148212312 0.465 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr20_-_61317891 0.464 NM_017798
YTHDF1
YTH domain family, member 1
chr16_-_1761710 0.461 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr3_+_38470782 0.461 NM_001106
ACVR2B
activin A receptor, type IIB
chr7_+_106472243 0.460 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr11_-_74740298 0.459 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr19_-_6453224 0.459 NM_006087
TUBB4
tubulin, beta 4
chr20_+_34667566 0.458 NM_018840
NM_199483
C20orf24

chromosome 20 open reading frame 24

chr5_-_132194122 0.454


chr4_-_1232742 0.454 CTBP1
C-terminal binding protein 1
chr6_-_119712596 0.454 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr2_-_6923215 0.453 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr8_+_144171271 0.452 LY6E
lymphocyte antigen 6 complex, locus E
chr6_+_37245860 0.452 NM_002648
PIM1
pim-1 oncogene
chr4_+_1842947 0.451 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr10_+_92970487 0.451 PCGF5
polycomb group ring finger 5
chr22_-_19686351 0.450 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr10_+_120779217 0.449 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr7_+_732831 0.449 NM_017802
HEATR2
HEAT repeat containing 2
chr16_+_65870891 0.449 NM_001129729
NM_001129731
PLEKHG4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

chr22_+_20101661 0.447 NM_015094
HIC2
hypermethylated in cancer 2
chr6_-_36518643 0.447 NM_152990
PXT1
peroxisomal, testis specific 1
chr6_+_36518521 0.447 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr8_+_144171275 0.447 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr6_-_143874463 0.446 NM_032020
FUCA2
fucosidase, alpha-L- 2, plasma
chr5_-_43075904 0.446 NM_001014279
C5orf39
chromosome 5 open reading frame 39
chr16_+_2465109 0.445 NM_020705
TBC1D24
TBC1 domain family, member 24
chr20_-_31725915 0.444 NM_031231
NM_031232
NECAB3

N-terminal EF-hand calcium binding protein 3

chr16_-_4604895 0.444 NM_145253
FAM100A
family with sequence similarity 100, member A
chr6_+_36518778 0.443 KCTD20
potassium channel tetramerisation domain containing 20
chr16_-_4341266 0.438 NM_016069
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 4.23e-16 GO:0044237 cellular metabolic process
1.18 1.63e-12 GO:0008152 metabolic process
1.34 2.15e-11 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 2.86e-11 GO:0044238 primary metabolic process
1.25 3.00e-11 GO:0044260 cellular macromolecule metabolic process
1.31 5.72e-11 GO:0034641 cellular nitrogen compound metabolic process
1.36 7.52e-11 GO:0009058 biosynthetic process
1.30 1.06e-10 GO:0006807 nitrogen compound metabolic process
1.36 1.39e-10 GO:0044249 cellular biosynthetic process
1.10 4.13e-10 GO:0009987 cellular process
1.94 1.01e-08 GO:0016568 chromatin modification
1.71 1.27e-08 GO:0051276 chromosome organization
1.82 1.63e-08 GO:0006325 chromatin organization
1.31 5.09e-08 GO:0010468 regulation of gene expression
1.33 2.55e-07 GO:0090304 nucleic acid metabolic process
1.25 4.82e-07 GO:0060255 regulation of macromolecule metabolic process
1.19 8.63e-07 GO:0043170 macromolecule metabolic process
1.50 9.30e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.22 1.05e-06 GO:0019222 regulation of metabolic process
1.30 2.27e-06 GO:0051252 regulation of RNA metabolic process
1.23 3.05e-06 GO:0031323 regulation of cellular metabolic process
1.23 3.49e-06 GO:0080090 regulation of primary metabolic process
1.29 4.08e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.33 9.73e-06 GO:0006464 protein modification process
1.32 1.00e-05 GO:0043412 macromolecule modification
1.34 1.18e-05 GO:0016070 RNA metabolic process
1.26 1.54e-05 GO:0009889 regulation of biosynthetic process
1.26 1.69e-05 GO:0031326 regulation of cellular biosynthetic process
1.35 1.75e-05 GO:0006996 organelle organization
1.27 2.62e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.59 2.80e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58 3.59e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.25 4.59e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 5.89e-05 GO:0050789 regulation of biological process
1.33 6.32e-05 GO:0034645 cellular macromolecule biosynthetic process
1.24 8.10e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.13 9.80e-05 GO:0050794 regulation of cellular process
1.28 1.03e-04 GO:0006355 regulation of transcription, DNA-dependent
1.32 1.03e-04 GO:0009059 macromolecule biosynthetic process
1.60 1.17e-04 GO:0051253 negative regulation of RNA metabolic process
2.05 1.23e-04 GO:0016569 covalent chromatin modification
1.56 1.34e-04 GO:0010629 negative regulation of gene expression
2.05 1.65e-04 GO:0016570 histone modification
1.11 3.33e-04 GO:0065007 biological regulation
1.53 3.34e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.58 3.97e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.43 5.05e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.24 7.26e-04 GO:0044267 cellular protein metabolic process
1.43 9.46e-04 GO:0006351 transcription, DNA-dependent
1.40 1.07e-03 GO:0009892 negative regulation of metabolic process
1.28 1.37e-03 GO:0010467 gene expression
1.48 1.67e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.49 1.82e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 2.17e-03 GO:0009890 negative regulation of biosynthetic process
1.37 3.38e-03 GO:0007049 cell cycle
1.38 3.92e-03 GO:0032774 RNA biosynthetic process
1.79 9.11e-03 GO:0032868 response to insulin stimulus
1.64 1.01e-02 GO:0043434 response to peptide hormone stimulus
1.22 1.03e-02 GO:0048519 negative regulation of biological process
1.38 1.27e-02 GO:0031324 negative regulation of cellular metabolic process
1.18 1.38e-02 GO:0016043 cellular component organization
1.55 1.59e-02 GO:0032583 regulation of gene-specific transcription
1.17 1.74e-02 GO:0071840 cellular component organization or biogenesis
1.56 2.91e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.60 3.62e-02 GO:0070647 protein modification by small protein conjugation or removal

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.01e-36 GO:0044424 intracellular part
1.16 1.04e-34 GO:0005622 intracellular
1.21 1.01e-29 GO:0043231 intracellular membrane-bounded organelle
1.21 1.25e-29 GO:0043227 membrane-bounded organelle
1.19 4.69e-28 GO:0043229 intracellular organelle
1.18 5.92e-28 GO:0043226 organelle
1.28 9.50e-23 GO:0005634 nucleus
1.44 7.41e-16 GO:0044428 nuclear part
1.22 1.54e-13 GO:0044446 intracellular organelle part
1.45 2.34e-13 GO:0031981 nuclear lumen
1.40 3.39e-13 GO:0070013 intracellular organelle lumen
1.39 3.67e-13 GO:0031974 membrane-enclosed lumen
1.15 6.06e-13 GO:0005737 cytoplasm
1.38 1.24e-12 GO:0043233 organelle lumen
1.21 2.30e-12 GO:0044422 organelle part
1.52 4.29e-12 GO:0005654 nucleoplasm
1.18 2.83e-10 GO:0044444 cytoplasmic part
1.05 6.74e-08 GO:0044464 cell part
1.05 7.15e-08 GO:0005623 cell
1.28 2.36e-05 GO:0005829 cytosol
1.49 2.49e-05 GO:0044451 nucleoplasm part
1.49 9.69e-04 GO:0005694 chromosome
1.30 1.49e-03 GO:0005739 mitochondrion
1.70 5.42e-03 GO:0000785 chromatin
1.15 1.80e-02 GO:0032991 macromolecular complex
3.64 2.01e-02 GO:0031519 PcG protein complex
1.43 2.79e-02 GO:0030529 ribonucleoprotein complex
1.45 2.84e-02 GO:0044427 chromosomal part
1.19 4.36e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.93e-15 GO:0005488 binding
1.32 1.71e-13 GO:0003676 nucleic acid binding
1.35 3.36e-10 GO:0003677 DNA binding
1.16 4.88e-10 GO:0005515 protein binding
1.38 2.17e-08 GO:0016740 transferase activity
1.18 7.26e-08 GO:0003824 catalytic activity
1.47 4.09e-07 GO:0030528 transcription regulator activity
1.82 6.31e-06 GO:0016564 transcription repressor activity
1.34 7.38e-06 GO:0032559 adenyl ribonucleotide binding
1.27 7.42e-06 GO:0000166 nucleotide binding
1.34 8.90e-06 GO:0030554 adenyl nucleotide binding
1.33 2.47e-05 GO:0005524 ATP binding
1.74 2.24e-04 GO:0008134 transcription factor binding
1.27 2.50e-04 GO:0032553 ribonucleotide binding
1.27 2.50e-04 GO:0032555 purine ribonucleotide binding
1.27 3.23e-04 GO:0017076 purine nucleotide binding
1.27 4.67e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.57 5.10e-04 GO:0016874 ligase activity
1.39 6.36e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.37 6.79e-04 GO:0001071 nucleic acid binding transcription factor activity
1.37 6.79e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.50 8.55e-04 GO:0042393 histone binding
1.66 1.22e-03 GO:0016563 transcription activator activity
1.16 1.48e-03 GO:0043167 ion binding
1.16 1.67e-03 GO:0043169 cation binding
1.16 2.18e-03 GO:0046872 metal ion binding
1.40 2.33e-03 GO:0016301 kinase activity
1.71 2.45e-03 GO:0016881 acid-amino acid ligase activity
1.67 2.52e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.23 3.30e-03 GO:0008270 zinc ion binding
1.41 4.05e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.38 4.83e-03 GO:0003723 RNA binding
1.82 5.16e-03 GO:0003682 chromatin binding
1.39 5.69e-03 GO:0019899 enzyme binding
1.52 6.54e-03 GO:0019904 protein domain specific binding
4.72 8.99e-03 GO:0042974 retinoic acid receptor binding
1.20 1.10e-02 GO:0046914 transition metal ion binding
5.03 1.36e-02 GO:0046965 retinoid X receptor binding
1.51 3.08e-02 GO:0003712 transcription cofactor activity
1.51 3.43e-02 GO:0000988 protein binding transcription factor activity
1.51 3.43e-02 GO:0000989 transcription factor binding transcription factor activity
1.78 4.68e-02 GO:0000287 magnesium ion binding
1.64 4.85e-02 GO:0019787 small conjugating protein ligase activity