Motif ID: SOX17.p2

Z-value: 1.314


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_555330470.562.4e-02Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_26105477 1.551 NM_001145454
NM_005563
 STMN1

stathmin 1

chr2_-_37752272 1.503 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr6_-_72187168 1.429 C6orf155
chromosome 6 open reading frame 155
chr14_-_22458220 1.421 NM_001077351
NM_001077352
NM_018107
 RBM23


RNA binding motif protein 23


chr18_-_21186107 1.417 NM_015461
 ZNF521
zinc finger protein 521
chr14_-_22458199 1.382 RBM23
RNA binding motif protein 23
chr14_-_22458134 1.345 RBM23
RNA binding motif protein 23
chr19_-_45888259 1.235 NM_004756
 NUMBL
numb homolog (Drosophila)-like
chr17_-_7996409 1.233 NM_002616
 PER1
period homolog 1 (Drosophila)
chr8_-_9046460 1.226 PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chrX_-_83644054 1.177 NM_001177478
NM_001177479
NM_144657
 HDX


highly divergent homeobox


chr12_-_6103945 1.148 NM_000552
 VWF
von Willebrand factor
chr8_-_120033240 1.144 NM_002546
 TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr19_+_47593137 1.109


chr2_-_144991386 1.058 ZEB2
zinc finger E-box binding homeobox 2
chr13_-_98428244 1.001 NM_001130048
NM_001130050
 DOCK9

dedicator of cytokinesis 9

chr11_+_113672378 0.997 NNMT
nicotinamide N-methyltransferase
chr14_-_37795001 0.997 CLEC14A
C-type lectin domain family 14, member A
chr8_-_93184629 0.976 NM_001198633
NM_175634
 RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr8_+_55533047 0.951 NM_022454
 SOX17
SRY (sex determining region Y)-box 17

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.54 1.07e-02 GO:0010628 positive regulation of gene expression
1.52 3.80e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.50 1.67e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.41 3.43e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.38 2.72e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.24 4.00e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.15 1.10e-04 GO:0050794 regulation of cellular process
1.13 8.02e-04 GO:0050789 regulation of biological process
1.11 2.09e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.30 1.08e-02 GO:0005856 cytoskeleton
1.16 2.08e-04 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.72 9.82e-03 GO:0003779 actin binding
1.49 8.54e-05 GO:0001071 nucleic acid binding transcription factor activity
1.49 8.54e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 3.71e-02 GO:0043565 sequence-specific DNA binding
1.23 1.81e-02 GO:0003677 DNA binding
1.10 3.10e-02 GO:0005515 protein binding