Motif ID: SOX17.p2

Z-value: 1.314


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_555330470.562.4e-02Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_26105477 1.551 NM_001145454
NM_005563
STMN1

stathmin 1

chr2_-_37752272 1.503 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr6_-_72187168 1.429 C6orf155
chromosome 6 open reading frame 155
chr14_-_22458220 1.421 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr18_-_21186107 1.417 NM_015461
ZNF521
zinc finger protein 521
chr14_-_22458199 1.382 RBM23
RNA binding motif protein 23
chr14_-_22458134 1.345 RBM23
RNA binding motif protein 23
chr19_-_45888259 1.235 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr17_-_7996409 1.233 NM_002616
PER1
period homolog 1 (Drosophila)
chr8_-_9046460 1.226 PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chrX_-_83644054 1.177 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr12_-_6103945 1.148 NM_000552
VWF
von Willebrand factor
chr8_-_120033240 1.144 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr19_+_47593137 1.109


chr2_-_144991386 1.058 ZEB2
zinc finger E-box binding homeobox 2
chr13_-_98428244 1.001 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr11_+_113672378 0.997 NNMT
nicotinamide N-methyltransferase
chr14_-_37795001 0.997 CLEC14A
C-type lectin domain family 14, member A
chr8_-_93184629 0.976 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr8_+_55533047 0.951 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr13_+_110653407 0.948 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr20_+_42644633 0.926 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr11_+_113672407 0.924 NNMT
nicotinamide N-methyltransferase
chr13_-_107317460 0.918 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr14_-_37795290 0.914 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr8_-_60194099 0.901 NM_014729
TOX
thymocyte selection-associated high mobility group box
chrX_+_15428820 0.899 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr14_-_87529600 0.899 NM_000153
NM_001037525
GALC

galactosylceramidase

chr9_+_81377419 0.897 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr13_-_32658215 0.890 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_37752731 0.886 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr11_-_4585947 0.883 NM_018073
TRIM68
tripartite motif containing 68
chr2_-_175578156 0.876 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr7_-_27171648 0.854 HOXA9
homeobox A9
chr7_-_99612757 0.845 NM_152742
GPC2
glypican 2
chr5_+_76047536 0.841 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr7_-_13995811 0.841 ETV1
ets variant 1
chr11_+_128068982 0.833 NM_002017
FLI1
Friend leukemia virus integration 1
chr7_-_27171673 0.811 NM_152739
HOXA9
homeobox A9
chr14_-_87529212 0.811 GALC
galactosylceramidase
chr12_+_84198015 0.809 NM_006982
ALX1
ALX homeobox 1
chr19_+_13767207 0.805 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chr2_-_128138435 0.800 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr10_+_70748581 0.789 NM_000188
HK1
hexokinase 1
chr10_+_17311242 0.788 VIM
vimentin
chr18_-_21185968 0.780 ZNF521
zinc finger protein 521
chr3_+_48482625 0.779 TREX1
three prime repair exonuclease 1
chr1_-_197173159 0.776 LOC100131234
familial acute myelogenous leukemia related factor
chr10_+_17311282 0.773 VIM
vimentin
chr7_+_148613304 0.772 LOC155060
AI894139 pseudogene
chr14_-_87529222 0.771 GALC
galactosylceramidase
chr17_-_59817456 0.765 PECAM1
platelet/endothelial cell adhesion molecule
chr1_-_26105230 0.763 NM_203401
STMN1
stathmin 1
chr1_+_149299530 0.756 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr10_+_17312654 0.751 VIM
vimentin
chr1_+_149299504 0.749 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_+_23711044 0.746 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr11_+_13646727 0.743 NM_032228
FAR1
fatty acyl CoA reductase 1
chr22_-_22511173 0.734 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr17_-_59817575 0.724 PECAM1
platelet/endothelial cell adhesion molecule
chr10_+_3099708 0.721 NM_002627
PFKP
phosphofructokinase, platelet
chr1_+_84539876 0.721 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr13_+_94052022 0.718 NM_180989
GPR180
G protein-coupled receptor 180
chr11_+_13646806 0.717 FAR1
fatty acyl CoA reductase 1
chr10_+_22765996 0.717 LOC100289455
hypothetical LOC100289455
chr3_+_44665220 0.703 NM_003420
ZNF35
zinc finger protein 35
chr17_-_59817654 0.702 PECAM1
platelet/endothelial cell adhesion molecule
chr10_+_31650069 0.699 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr5_-_88214720 0.695 MEF2C
myocyte enhancer factor 2C
chr10_+_17311283 0.691 VIM
vimentin
chr1_+_149299490 0.691 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr9_+_81377289 0.689 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr14_+_102659464 0.685 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr5_+_177564102 0.685 NM_004499
NM_031266
HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

chr7_-_27171600 0.682 HOXA9
homeobox A9
chr11_+_128069165 0.682 FLI1
Friend leukemia virus integration 1
chr2_-_188021117 0.678 NM_005795
CALCRL
calcitonin receptor-like
chr10_+_17311307 0.677 VIM
vimentin
chr17_-_59817722 0.672 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr14_+_85066265 0.669 FLRT2
fibronectin leucine rich transmembrane protein 2
chr14_+_62740878 0.664 NM_020663
RHOJ
ras homolog gene family, member J
chr3_+_100840129 0.663 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr7_-_130891861 0.662 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr5_+_177564139 0.659 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr8_+_60194328 0.656


chr4_+_151218862 0.654 NM_001040260
NM_001040261
DCLK2

doublecortin-like kinase 2

chr11_-_6633427 0.651 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr14_+_85066207 0.642 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_+_27102197 0.638


chr5_+_95093267 0.628


chr8_+_26491507 0.618 DPYSL2
dihydropyrimidinase-like 2
chrX_-_50403412 0.617 SHROOM4
shroom family member 4
chr17_-_59131210 0.608 NM_030576
LIMD2
LIM domain containing 2
chr5_+_14493905 0.607 TRIO
triple functional domain (PTPRF interacting)
chr7_-_27102049 0.601 NM_005522
NM_153620
HOXA1

homeobox A1

chr6_-_56824371 0.601 DST
dystonin
chr14_+_23710924 0.600 REC8
REC8 homolog (yeast)
chr6_+_116939500 0.598 NM_153711
FAM26E
family with sequence similarity 26, member E
chr5_-_111782637 0.597 NM_022140
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr9_-_35101592 0.596 KIAA1539
KIAA1539
chr19_+_54723044 0.595 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr19_+_17281216 0.586 NM_024050
DDA1
DET1 and DDB1 associated 1
chr6_-_85529884 0.586 TBX18
T-box 18
chr3_+_158637273 0.586 NM_002852
PTX3
pentraxin 3, long
chr5_+_40715799 0.585 PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr11_+_128069183 0.584 FLI1
Friend leukemia virus integration 1
chr5_-_146813343 0.584 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr12_-_24946495 0.582 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr8_-_70907957 0.579 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr19_+_17281352 0.579 DDA1
DET1 and DDB1 associated 1
chr14_-_99842519 0.579 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr3_+_48482213 0.576 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr4_-_2233606 0.576 MXD4
MAX dimerization protein 4
chr6_+_27222839 0.573 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr5_+_40715778 0.570 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr19_+_17281374 0.565 DDA1
DET1 and DDB1 associated 1
chr12_+_74160779 0.562 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr3_-_161650294 0.560 NM_173084
TRIM59
tripartite motif containing 59
chr8_-_70908130 0.558 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_139654807 0.558 NM_153235
TXLNB
taxilin beta
chr14_+_102870301 0.557 EIF5
eukaryotic translation initiation factor 5
chr3_+_25444753 0.555 NM_016152
RARB
retinoic acid receptor, beta
chr1_+_45565126 0.554 NM_032756
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr7_+_150321771 0.554 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr19_-_51856129 0.550 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr9_-_35101534 0.548 KIAA1539
KIAA1539
chr11_+_128069203 0.545 FLI1
Friend leukemia virus integration 1
chr3_-_161650219 0.539 TRIM59
tripartite motif containing 59
chr8_-_101187346 0.537 RGS22
regulator of G-protein signaling 22
chr19_-_6230797 0.535


chr1_-_68470585 0.534 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr7_+_27102508 0.532


chr7_-_5535726 0.532 ACTB
actin, beta
chr2_-_144991556 0.528 ZEB2
zinc finger E-box binding homeobox 2
chr14_+_102870431 0.527 EIF5
eukaryotic translation initiation factor 5
chr9_+_89302574 0.526 NM_004938
DAPK1
death-associated protein kinase 1
chr2_-_56266408 0.525 LOC100129434
hypothetical LOC100129434
chr21_-_14840506 0.525 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_+_14409875 0.524 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr17_-_1478293 0.522 SLC43A2
solute carrier family 43, member 2
chr13_-_29937966 0.521 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr5_-_124108672 0.520 NM_020747
ZNF608
zinc finger protein 608
chr19_+_50086362 0.518 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_-_5535432 0.517 ACTB
actin, beta
chr5_+_95092384 0.516 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr11_+_13646839 0.514 FAR1
fatty acyl CoA reductase 1
chr4_-_2233504 0.513 NM_006454
MXD4
MAX dimerization protein 4
chr6_-_56824672 0.512 DST
dystonin
chr12_-_21701985 0.511 NM_001174097
LDHB
lactate dehydrogenase B
chr15_-_46257611 0.509 MYEF2
myelin expression factor 2
chr5_-_136862317 0.509 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr11_+_13646822 0.506 FAR1
fatty acyl CoA reductase 1
chrX_+_12903145 0.505 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr1_+_149299307 0.496 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_-_8268666 0.495 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr12_-_21702000 0.493 LDHB
lactate dehydrogenase B
chr4_-_81212737 0.491 ANTXR2
anthrax toxin receptor 2
chr1_-_43692134 0.490 NM_001190880
NM_031207
HYI

hydroxypyruvate isomerase (putative)

chr7_+_26158257 0.490 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr13_-_100125028 0.488 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr12_-_21702021 0.486 LDHB
lactate dehydrogenase B
chr17_-_44010543 0.485 NM_024015
HOXB4
homeobox B4
chr10_+_17311347 0.484 VIM
vimentin
chr12_-_21702036 0.484 LDHB
lactate dehydrogenase B
chr14_+_102870245 0.481 NM_001969
EIF5
eukaryotic translation initiation factor 5
chr13_-_29938029 0.480 NM_002128
HMGB1
high-mobility group box 1
chr3_-_170347019 0.478 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr5_+_66160359 0.474 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr20_-_55718982 0.473 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr8_+_1759502 0.473 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr9_+_123501186 0.471 DAB2IP
DAB2 interacting protein
chr22_-_37481925 0.468 SUN2
Sad1 and UNC84 domain containing 2
chr17_-_59818033 0.466 PECAM1
platelet/endothelial cell adhesion molecule
chr12_-_21702046 0.466 NM_002300
LDHB
lactate dehydrogenase B
chr5_+_177564140 0.466 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr10_+_70748633 0.464 HK1
hexokinase 1
chr11_-_64247230 0.462 NM_015080
NM_138732
NRXN2

neurexin 2

chr11_-_27679022 0.461 NM_001143812
BDNF
brain-derived neurotrophic factor
chr14_+_102870287 0.457 EIF5
eukaryotic translation initiation factor 5
chr15_-_43457916 0.455 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr9_+_4480193 0.454 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr10_+_17311962 0.454 VIM
vimentin
chr7_+_134114957 0.450 CALD1
caldesmon 1
chr12_-_46499834 0.447 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr1_-_26105954 0.447 NM_203399
STMN1
stathmin 1
chr19_+_50086357 0.444 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr19_+_50086299 0.443 NM_001128916
NM_001128917
NM_006114
TOMM40


translocase of outer mitochondrial membrane 40 homolog (yeast)


chr6_-_27222556 0.440 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr6_-_53321658 0.440 ELOVL5
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr5_-_141318810 0.434 NM_016580
PCDH12
protocadherin 12
chr10_-_14686243 0.434 FAM107B
family with sequence similarity 107, member B
chr1_+_43539239 0.433 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr5_-_136862130 0.432 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr2_+_12775814 0.431


chr1_+_145479805 0.431 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr15_-_42274760 0.427 FRMD5
FERM domain containing 5
chr7_+_134114912 0.426 CALD1
caldesmon 1
chr5_-_137099602 0.426 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr7_+_115637795 0.426 NM_015641
TES
testis derived transcript (3 LIM domains)
chr3_+_174598937 0.423 NM_014932
NLGN1
neuroligin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.15 1.10e-04 GO:0050794 regulation of cellular process
1.13 8.02e-04 GO:0050789 regulation of biological process
1.54 1.07e-02 GO:0010628 positive regulation of gene expression
1.50 1.67e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.11 2.09e-02 GO:0065007 biological regulation
1.38 2.72e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.41 3.43e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.52 3.80e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.24 4.00e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 2.08e-04 GO:0005634 nucleus
1.30 1.08e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 8.54e-05 GO:0001071 nucleic acid binding transcription factor activity
1.49 8.54e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.72 9.82e-03 GO:0003779 actin binding
1.23 1.81e-02 GO:0003677 DNA binding
1.10 3.10e-02 GO:0005515 protein binding
1.45 3.71e-02 GO:0043565 sequence-specific DNA binding