Motif ID: NFE2L2.p2

Z-value: 1.842


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_1778381040.731.2e-03Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_977163 4.959 NM_022042
NM_134425
NM_213613
 SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr19_-_54350457 3.512 NM_002152
 HRC
histidine rich calcium binding protein
chr7_+_37926943 3.498 EPDR1
ependymin related protein 1 (zebrafish)
chr22_+_43451600 3.434 PRR5
proline rich 5 (renal)
chr10_-_76538859 3.319 NM_001007271
NM_001007272
NM_001007273
 DUSP13


dual specificity phosphatase 13


chr1_-_156923111 3.218 NM_003126
 SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr22_+_43451351 3.020 NM_001017530
NM_001198721
NM_015366
 PRR5


proline rich 5 (renal)


chr16_-_28528149 2.928 NM_177530
NM_177534
 SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr20_+_34206070 2.888 NM_012156
 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr16_+_2023279 2.661 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chrX_-_154216929 2.659 NM_001289
 CLIC2
chloride intracellular channel 2
chr22_+_19699441 2.642 NM_001159554
NM_005446
 P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr19_-_53914768 2.618 NM_001130915
 MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr16_+_88515917 2.602 NM_001197181
 TUBB3
tubulin, beta 3
chrX_-_100527799 2.559 NM_000061
 BTK
Bruton agammaglobulinemia tyrosine kinase
chrX_+_9391314 2.488 NM_001139466
NM_001139467
NM_001139468
 TBL1X


transducin (beta)-like 1X-linked


chr9_-_126309510 2.466 NM_004959
 NR5A1
nuclear receptor subfamily 5, group A, member 1
chr12_+_54361685 2.464 METTL7B
methyltransferase like 7B
chr11_+_118463906 2.335 NM_001024382
 HMBS
hydroxymethylbilane synthase
chr17_-_25642962 2.289 NM_000386
 BLMH
bleomycin hydrolase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
5.02 5.94e-03 GO:0006521 regulation of cellular amino acid metabolic process
4.36 2.79e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
4.36 2.79e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
4.36 2.79e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
4.36 2.79e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
4.36 2.79e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
4.36 2.79e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
4.36 2.79e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
4.36 2.79e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
4.33 1.22e-03 GO:0051351 positive regulation of ligase activity
4.16 4.64e-02 GO:0033238 regulation of cellular amine metabolic process
4.16 4.64e-02 GO:0071158 positive regulation of cell cycle arrest
4.06 2.81e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.98 1.69e-02 GO:0051443 positive regulation of ubiquitin-protein ligase activity
3.77 8.07e-03 GO:0051340 regulation of ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
4.58 1.14e-03 GO:0000502 proteasome complex
1.27 1.03e-02 GO:0005886 plasma membrane
1.26 1.88e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
4.99 2.50e-02 GO:0003823 antigen binding