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• Activity deltas table
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Motif ID: NFE2L1.p2

Z-value: 2.070

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_-_63333487	4.089		DSEL	dermatan sulfate epimerase-like
chr9_-_16717887	3.018		BNC2	basonuclin 2
chr20_+_19903778	2.935		RIN2	Ras and Rab interactor 2
chr8_-_108579270	2.870	NM_001146	ANGPT1	angiopoietin 1
chr9_-_14303509	2.527		NFIB	nuclear factor I/B
chr1_-_68470585	2.370	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr5_+_148186348	2.343	NM_000024	ADRB2	adrenergic, beta-2-, receptor, surface
chr1_-_197173159	2.320		LOC100131234	familial acute myelogenous leukemia related factor
chr16_+_81218074	2.281	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr15_+_65205107	2.277	NM_001145102	SMAD3	SMAD family member 3
chrX_+_86659370	2.211	NM_019117 NM_057162	KLHL4	kelch-like 4 (Drosophila)
chr3_+_29297806	2.192	NM_001003792 NM_001003793 NM_001177711 NM_001177712 NM_014483	RBMS3	RNA binding motif, single stranded interacting protein 3
chr1_-_59020875	2.023		JUN	jun proto-oncogene
chr2_-_160764819	2.018	NM_000888	ITGB6	integrin, beta 6
chr5_+_36644187	1.999	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_119506446	1.975		TLR4	toll-like receptor 4
chr16_+_81218142	1.953		CDH13	cadherin 13, H-cadherin (heart)
chr4_+_183302105	1.882		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr9_+_119506428	1.864		TLR4	toll-like receptor 4
chr7_+_150442652	1.862		AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr11_-_123353607	1.843	NM_001004474	OR10S1	olfactory receptor, family 10, subfamily S, member 1
chr7_+_116447527	1.830		ST7	suppression of tumorigenicity 7
chr9_-_14303899	1.812		NFIB	nuclear factor I/B
chr9_-_14303943	1.810		NFIB	nuclear factor I/B
chr7_+_134114912	1.802		CALD1	caldesmon 1
chr7_-_27153892	1.792	NM_024014	HOXA6	homeobox A6
chr2_-_164300758	1.782	NM_018086	FIGN	fidgetin
chr20_-_22978141	1.765	NM_000361	THBD	thrombomodulin
chr2_-_105381855	1.759	NM_001039492 NM_001450 NM_201555	FHL2	four and a half LIM domains 2
chr9_+_119506274	1.749	NM_138554	TLR4	toll-like receptor 4
chr11_-_8788765	1.749	NM_213618	ST5	suppression of tumorigenicity 5
chr17_-_37034288	1.748	NM_000422	KRT17	keratin 17
chr13_-_98428244	1.745	NM_001130048 NM_001130050	DOCK9	dedicator of cytokinesis 9
chr6_-_10527772	1.696	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr12_+_13240868	1.686	NM_001423	EMP1	epithelial membrane protein 1
chr10_+_128583984	1.676	NM_001380	DOCK1	dedicator of cytokinesis 1
chr9_-_131555111	1.659	NM_004878	PTGES	prostaglandin E synthase
chr17_-_36996611	1.659	NM_000526	KRT14	keratin 14
chr12_+_13240987	1.652		EMP1	epithelial membrane protein 1
chr12_+_13240983	1.639		EMP1	epithelial membrane protein 1
chr7_-_27149750	1.578	NM_019102	HOXA5	homeobox A5
chr7_-_13992351	1.569	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr10_-_92671005	1.531	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr10_-_92670764	1.530		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr3_+_25445071	1.465		RARB	retinoic acid receptor, beta
chrX_+_106956115	1.462		MID2	midline 2
chr21_-_35343065	1.449		RUNX1	runt-related transcription factor 1
chr5_-_54317102	1.429	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr4_-_177950658	1.393	NM_005429	VEGFC	vascular endothelial growth factor C
chr12_-_51173238	1.389	NM_005554	KRT6A	keratin 6A
chr2_+_201182187	1.382		AOX1	aldehyde oxidase 1
chr2_-_101457596	1.377	NM_001145664	RFX8	regulatory factor X, 8
chr4_-_75183860	1.375	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chrX_-_99778340	1.342	NM_003270	TSPAN6	tetraspanin 6
chr18_+_54681657	1.314		ZNF532	zinc finger protein 532
chr11_-_65860450	1.305	NM_004292	RIN1	Ras and Rab interactor 1
chr3_-_71262405	1.293		FOXP1	forkhead box P1
chr5_+_52320660	1.287	NM_002203	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr5_-_94443300	1.285	NM_001002796	MCTP1	multiple C2 domains, transmembrane 1
chr3_-_71262426	1.268		FOXP1	forkhead box P1
chr11_-_85107569	1.258	NM_206929	SYTL2	synaptotagmin-like 2
chr10_+_124211353	1.250		HTRA1	HtrA serine peptidase 1
chr7_-_78920806	1.238	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_37847095	1.230		RAB11FIP1	RAB11 family interacting protein 1 (class I)
chr7_+_116447499	1.225		ST7	suppression of tumorigenicity 7
chr7_-_27108826	1.223	NM_006735	HOXA2	homeobox A2
chr8_+_70541631	1.222		SULF1	sulfatase 1
chr13_+_113546943	1.209		GAS6	growth arrest-specific 6
chrX_+_99785818	1.205	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr16_+_56219802	1.195	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr5_-_58607673	1.188	NM_001197220	PDE4D	phosphodiesterase 4D, cAMP-specific
chr18_-_51219880	1.185		TCF4	transcription factor 4
chr2_-_160765008	1.183		ITGB6	integrin, beta 6
chr4_-_159311959	1.182		FAM198B	family with sequence similarity 198, member B
chrX_+_99786044	1.171		SRPX2	sushi-repeat containing protein, X-linked 2
chr3_-_45242072	1.167		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr4_+_30331543	1.163		PCDH7	protocadherin 7
chr1_-_23393808	1.160	NM_000864	HTR1D	5-hydroxytryptamine (serotonin) receptor 1D
chr5_-_16561936	1.153	NM_019000	FAM134B	family with sequence similarity 134, member B
chr19_+_12996745	1.151		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr7_-_41709191	1.149	NM_002192	INHBA	inhibin, beta A
chr4_+_86918882	1.149		ARHGAP24	Rho GTPase activating protein 24
chr1_-_156784518	1.141	NM_001005189	OR6Y1	olfactory receptor, family 6, subfamily Y, member 1
chr19_-_55008172	1.141	NM_001171937 NM_025129	FUZ	fuzzy homolog (Drosophila)
chr12_+_79625538	1.140	NM_002469	MYF6	myogenic factor 6 (herculin)
chr13_+_113546841	1.139	NM_000820	GAS6	growth arrest-specific 6
chr15_-_37999519	1.139
chr8_-_102029997	1.130		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_+_171619346	1.128	NM_005602	CLDN11	claudin 11
chr3_-_113842553	1.117		CCDC80	coiled-coil domain containing 80
chr15_+_99207555	1.117		LOC145757	hypothetical LOC145757
chr4_+_30331289	1.115		PCDH7	protocadherin 7
chr12_-_50871953	1.109	NM_001081492 NM_182507	KRT80	keratin 80
chr5_+_35892747	1.103	NM_002185	IL7R	interleukin 7 receptor
chr1_-_20682541	1.102
chr3_-_113842652	1.076	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr1_-_58815753	1.072	NM_002353	TACSTD2	tumor-associated calcium signal transducer 2
chr8_+_70541412	1.059	NM_001128204 NM_015170	SULF1	sulfatase 1
chr11_+_12355600	1.044	NM_018222	PARVA	parvin, alpha
chr10_+_75343352	1.042		PLAU	plasminogen activator, urokinase
chrX_-_62891066	1.042		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr10_-_23673777	1.041	NM_153714	C10orf67	chromosome 10 open reading frame 67
chr1_+_199519202	1.039	NM_000299 NM_001005337	PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr7_+_134114701	1.037	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr3_-_64647325	1.031		ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9
chrX_-_10548458	1.029	NM_000381 NM_033289	MID1	midline 1 (Opitz/BBB syndrome)
chr1_-_58815415	1.027		TACSTD2	tumor-associated calcium signal transducer 2
chr5_+_174084137	1.023	NM_002449	MSX2	msh homeobox 2
chr3_-_116272911	1.021	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chr18_-_57711283	1.006	NM_173557	RNF152	ring finger protein 152
chr7_+_134114957	1.001		CALD1	caldesmon 1
chr3_+_25444837	0.996	NM_000965	RARB	retinoic acid receptor, beta
chr6_-_112682573	0.996		LAMA4	laminin, alpha 4
chr2_+_220017617	0.993		SPEG	SPEG complex locus
chr9_+_108665168	0.981	NM_021224	ZNF462	zinc finger protein 462
chr10_+_123862430	0.974		TACC2	transforming, acidic coiled-coil containing protein 2
chr1_-_153209625	0.969	NM_001130040 NM_183001	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr9_+_88953378	0.963	NM_001001709	C9orf170	chromosome 9 open reading frame 170
chr12_+_13045702	0.962		HTR7P1	5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr1_+_183970093	0.955	NM_031935	HMCN1	hemicentin 1
chr17_-_37828643	0.953	NM_012232	PTRF	polymerase I and transcript release factor
chr12_+_12829807	0.951	NM_030817	APOLD1	apolipoprotein L domain containing 1
chr11_+_34599163	0.950	NM_012153	EHF	ets homologous factor
chr9_-_106420305	0.932	NM_001001956	OR13C9	olfactory receptor, family 13, subfamily C, member 9
chr2_-_65447267	0.927		SPRED2	sprouty-related, EVH1 domain containing 2
chr8_-_72431274	0.925	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr10_-_33663305	0.919		NRP1	neuropilin 1
chr2_-_65447370	0.916	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr21_-_35343428	0.916		RUNX1	runt-related transcription factor 1
chr6_-_112682459	0.915	NM_001105206 NM_001105207 NM_001105208 NM_001105209 NM_002290	LAMA4	laminin, alpha 4
chr3_+_25444753	0.915	NM_016152	RARB	retinoic acid receptor, beta
chr21_-_35343331	0.911		RUNX1	runt-related transcription factor 1
chr9_+_136673534	0.906		COL5A1	collagen, type V, alpha 1
chr3_+_64645819	0.904		LOC100507098	hypothetical LOC100507098
chr9_+_35528628	0.904	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr7_+_27191534	0.901		HOXA11-AS1	HOXA11 antisense RNA 1 (non-protein coding)
chr4_-_75123193	0.896	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chr4_-_75183700	0.885		CXCL2	chemokine (C-X-C motif) ligand 2
chr11_+_131285747	0.877	NM_001144058 NM_001144059 NM_016522	NTM	neurotrimin
chr17_-_7434113	0.874	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr18_+_54682261	0.873		ZNF532	zinc finger protein 532
chr16_+_53522611	0.859	NM_005853	IRX5	iroquois homeobox 5
chr13_-_32658215	0.854	NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr2_+_206255597	0.852		NRP2	neuropilin 2
chr2_-_165186064	0.850		GRB14	growth factor receptor-bound protein 14
chr4_+_126457016	0.847	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr4_+_74953971	0.846	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr20_+_59260847	0.845	NM_001794	CDH4	cadherin 4, type 1, R-cadherin (retinal)
chr6_+_1556543	0.843		FOXC1	forkhead box C1
chr1_+_68070573	0.842
chr7_-_27158726	0.841
chr17_-_36475652	0.838	NM_033184	KRTAP2-4	keratin associated protein 2-4
chr7_-_27191287	0.836	NM_005523	HOXA11	homeobox A11
chr1_+_200775864	0.832	NM_001197131	PPP1R12B	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr6_+_116939500	0.830	NM_153711	FAM26E	family with sequence similarity 26, member E
chr12_-_94135154	0.828	NM_018351	FGD6	FYVE, RhoGEF and PH domain containing 6
chr1_-_154205675	0.824		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr16_+_85101734	0.823		FOXF1	forkhead box F1
chr11_+_7574992	0.821		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_-_33267646	0.817	NM_000109	DMD	dystrophin
chr11_+_12652427	0.806	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr10_+_11100111	0.804		CELF2	CUGBP, Elav-like family member 2
chr17_-_35510074	0.802		NR1D1	nuclear receptor subfamily 1, group D, member 1
chr15_-_37999717	0.800		GPR176	G protein-coupled receptor 176
chr5_-_124108672	0.798	NM_020747	ZNF608	zinc finger protein 608
chr6_-_56615544	0.797	NM_001723 NM_015548	DST	dystonin
chr2_-_40593074	0.793	NM_001112802	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr11_+_101485946	0.792	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr5_-_9599157	0.791	NM_003966	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_-_122722674	0.787	NM_005328	HAS2	hyaluronan synthase 2
chr6_+_147871477	0.781	NM_001030060	SAMD5	sterile alpha motif domain containing 5
chr19_+_12996830	0.780		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr13_-_32757835	0.778	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr11_-_119504726	0.777		TRIM29	tripartite motif containing 29
chr14_+_20580224	0.777	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr7_-_27162688	0.776	NM_006896	HOXA7	homeobox A7
chr13_-_107317460	0.772	NM_001080396	FAM155A	family with sequence similarity 155, member A
chr15_+_60838053	0.769		TLN2	talin 2
chr16_+_85101605	0.764	NM_001451	FOXF1	forkhead box F1
chr4_-_177427252	0.760	NM_080874	ASB5	ankyrin repeat and SOCS box containing 5
chr14_+_51850754	0.758	NM_000956	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa
chrX_+_106956158	0.757		MID2	midline 2
chr10_-_33663777	0.754	NM_001024628 NM_001024629 NM_003873	NRP1	neuropilin 1
chr21_-_35343448	0.749		RUNX1	runt-related transcription factor 1
chr15_+_73728402	0.747	NM_153271	SNX33	sorting nexin 33
chr3_-_69674412	0.746		FRMD4B	FERM domain containing 4B
chr10_-_33663984	0.742		NRP1	neuropilin 1
chr10_-_64698831	0.739	NM_004241	JMJD1C	jumonji domain containing 1C
chr11_+_19691397	0.736	NM_145117 NM_182964	NAV2	neuron navigator 2
chr1_-_95165089	0.736	NM_001839	CNN3	calponin 3, acidic
chr15_+_90198567	0.735		SLCO3A1	solute carrier organic anion transporter family, member 3A1
chrX_+_73557809	0.734	NM_006517	SLC16A2	solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr11_+_123625632	0.734	NM_001002905	OR8G1	olfactory receptor, family 8, subfamily G, member 1
chr9_-_14304036	0.732	NM_001190737 NM_005596	NFIB	nuclear factor I/B
chr21_-_35343456	0.730	NM_001754	RUNX1	runt-related transcription factor 1
chr5_+_60663842	0.728	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chrX_+_106955737	0.728	NM_012216 NM_052817	MID2	midline 2
chr15_+_41597097	0.727	NM_002373	MAP1A	microtubule-associated protein 1A
chr7_-_83662152	0.727	NM_006080	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_95165037	0.726		CNN3	calponin 3, acidic

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.35	1.60e-26	GO:0007608	sensory perception of smell
2.16	2.32e-22	GO:0007606	sensory perception of chemical stimulus
1.51	8.92e-18	GO:0003008	system process
1.73	5.06e-16	GO:0007600	sensory perception
1.55	1.13e-15	GO:0050877	neurological system process
1.22	9.23e-13	GO:0032501	multicellular organismal process
1.17	3.72e-09	GO:0050896	response to stimulus
1.22	1.81e-05	GO:0048856	anatomical structure development
1.23	2.37e-05	GO:0048731	system development
1.52	2.47e-03	GO:0072358	cardiovascular system development
1.52	2.47e-03	GO:0072359	circulatory system development
1.46	3.70e-03	GO:0048666	neuron development
1.16	3.82e-03	GO:0032502	developmental process
1.28	3.86e-03	GO:0009653	anatomical structure morphogenesis
1.21	3.95e-03	GO:0048522	positive regulation of cellular process
1.17	5.31e-03	GO:0007275	multicellular organismal development
1.43	6.14e-03	GO:0030030	cell projection organization
1.27	7.43e-03	GO:0007399	nervous system development
1.25	9.51e-03	GO:0023051	regulation of signaling
1.63	1.90e-02	GO:0061061	muscle structure development
1.26	1.98e-02	GO:0009966	regulation of signal transduction
1.46	1.99e-02	GO:0031175	neuron projection development
1.40	2.49e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.21	3.16e-02	GO:0048869	cellular developmental process
1.20	3.30e-02	GO:0048523	negative regulation of cellular process
1.33	3.55e-02	GO:0022008	neurogenesis
1.18	3.59e-02	GO:0048518	positive regulation of biological process
1.34	3.70e-02	GO:0048699	generation of neurons
1.21	3.77e-02	GO:0030154	cell differentiation
1.59	3.91e-02	GO:0001944	vasculature development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.25	2.93e-13	GO:0005886	plasma membrane
1.25	3.03e-13	GO:0071944	cell periphery
1.11	1.92e-06	GO:0016020	membrane
1.29	4.04e-05	GO:0005856	cytoskeleton
1.48	7.30e-05	GO:0030054	cell junction
1.37	4.66e-04	GO:0042995	cell projection
1.10	2.37e-03	GO:0044425	membrane part
1.50	4.43e-03	GO:0043005	neuron projection
1.17	6.83e-03	GO:0043228	non-membrane-bounded organelle
1.17	6.83e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.28	1.33e-02	GO:0044430	cytoskeletal part
1.76	1.83e-02	GO:0005912	adherens junction
1.46	1.83e-02	GO:0045202	synapse
2.73	2.76e-02	GO:0030119	AP-type membrane coat adaptor complex
1.65	2.99e-02	GO:0030425	dendrite
1.84	3.42e-02	GO:0030016	myofibril
1.69	3.60e-02	GO:0070161	anchoring junction
1.51	3.91e-02	GO:0015629	actin cytoskeleton
1.84	4.20e-02	GO:0044449	contractile fiber part
2.73	4.76e-02	GO:0030131	clathrin adaptor complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.37	1.05e-26	GO:0004984	olfactory receptor activity
1.67	1.96e-14	GO:0004930	G-protein coupled receptor activity
1.39	1.27e-07	GO:0004888	transmembrane receptor activity
1.27	2.77e-04	GO:0004872	receptor activity
1.22	1.09e-03	GO:0004871	signal transducer activity
1.22	1.09e-03	GO:0060089	molecular transducer activity
1.09	8.03e-03	GO:0005515	protein binding
1.39	3.83e-02	GO:0008092	cytoskeletal protein binding