Motif ID: FOXP3.p2

Z-value: 1.221


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXP3chrX_-_490081150.665.5e-03Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_100527799 5.448 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr9_-_70780574 4.145


chr4_+_39874921 3.714 NM_004310
RHOH
ras homolog gene family, member H
chr2_-_17563186 2.384 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr6_-_11887265 2.060 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr9_-_99740243 2.021 NM_197978
HEMGN
hemogen
chr6_-_6632197 1.525


chr14_+_19655405 1.518 NM_001004715
OR4K17
olfactory receptor, family 4, subfamily K, member 17
chr1_-_205161821 1.495 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr22_+_20316968 1.426 NM_152612
CCDC116
coiled-coil domain containing 116
chr1_-_158815895 1.420 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr10_+_5976354 1.371 NM_032807
FBXO18
F-box protein, helicase, 18
chr12_-_55929189 1.256


chr7_-_142369519 1.215 KEL
Kell blood group, metallo-endopeptidase
chr1_+_173111306 1.180 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_158815850 1.177 CD84
CD84 molecule
chr12_-_8110268 1.129 C3AR1
complement component 3a receptor 1
chr17_-_31281398 1.087 NM_001163122
NM_001163124
NM_001163125
NM_001163130
RDM1



RAD52 motif 1



chr2_-_158008763 1.070 NM_004288
CYTIP
cytohesin 1 interacting protein
chr12_-_8110196 1.063 NM_004054
C3AR1
complement component 3a receptor 1
chr1_+_205694237 1.063 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr2_+_65517316 1.012 FLJ16124
FLJ16124 protein
chr1_+_156490550 0.972 NM_001763
CD1A
CD1a molecule
chr22_+_19458378 0.925 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr6_-_154719560 0.895 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr7_-_142369534 0.888 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr6_-_32605898 0.874 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr19_+_17723285 0.870 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr6_+_64414389 0.864 NM_015153
PHF3
PHD finger protein 3
chr11_+_58668827 0.859 NM_022074
NM_198847
FAM111A

family with sequence similarity 111, member A

chr3_-_19950675 0.848 NM_144715
EFHB
EF-hand domain family, member B
chr6_+_144227265 0.812 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr10_+_49563520 0.780 NM_020945
WDFY4
WDFY family member 4
chr1_+_159959072 0.755 NM_001002901
FCRLB
Fc receptor-like B
chrX_-_76824726 0.739 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr2_+_102401580 0.728 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr19_-_50271527 0.687 NM_145288
ZNF296
zinc finger protein 296
chr7_+_21434818 0.680


chr16_+_2807228 0.676 PRSS21
protease, serine, 21 (testisin)
chr10_+_51246290 0.664 NM_001145262
NCOA4
nuclear receptor coactivator 4
chr6_-_32665409 0.659 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr16_+_31446703 0.656 NM_016633
AHSP
alpha hemoglobin stabilizing protein
chrX_+_134803450 0.656 NM_018666
SAGE1
sarcoma antigen 1
chr17_+_49255237 0.639 NM_032559
KIF2B
kinesin family member 2B
chr21_-_32879617 0.631 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr11_+_59580705 0.627 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr4_-_145281237 0.627 NM_002099
GYPA
glycophorin A (MNS blood group)
chr19_-_60458915 0.619 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr8_-_110724594 0.606 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr4_+_22608252 0.604


chr5_+_40877053 0.603 NM_032587
CARD6
caspase recruitment domain family, member 6
chr11_-_5487728 0.579 NM_017481
UBQLN3
ubiquilin 3
chr6_+_106653429 0.577 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr1_+_15862887 0.571


chr9_-_138762725 0.564 NM_198946
LCN6
lipocalin 6
chr1_+_40631603 0.551 NM_001198979
SMAP2
small ArfGAP2
chr17_-_8215577 0.543 NM_213597
KRBA2
KRAB-A domain containing 2
chr4_-_123596921 0.542 NM_000586
IL2
interleukin 2
chr8_+_107807415 0.541 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr19_-_44060729 0.528 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr6_+_31838751 0.517 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr21_-_33107813 0.507 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr3_-_10309600 0.501 NM_001134944
NM_001134945
NM_001134946
GHRL


ghrelin/obestatin prepropeptide


chr2_+_108360798 0.499 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_116727514 0.488 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr16_+_2807164 0.488 NM_006799
NM_144956
NM_144957
PRSS21


protease, serine, 21 (testisin)


chr1_-_51560469 0.487 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr12_+_49604782 0.483 NM_014033
METTL7A
methyltransferase like 7A
chr17_-_64462976 0.478 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr15_-_78050515 0.478 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr1_+_23994914 0.471


chr16_+_56567839 0.466 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr5_+_34723420 0.460 NM_001145523
RAI14
retinoic acid induced 14
chr5_-_32424352 0.451 ZFR
zinc finger RNA binding protein
chr6_-_25982418 0.442 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr5_-_32424444 0.442 ZFR
zinc finger RNA binding protein
chr1_-_151310707 0.430 NM_001017418
SPRR2B
small proline-rich protein 2B
chr11_+_59580630 0.424 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr1_+_196874759 0.424 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_67404756 0.423 NM_144701
IL23R
interleukin 23 receptor
chr5_-_37220702 0.422 C5orf42
chromosome 5 open reading frame 42
chr11_-_72057755 0.422 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr14_-_34414603 0.417 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chr17_-_64752550 0.416 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr13_+_107753764 0.413


chr11_+_63730720 0.412 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr15_+_19869841 0.401 NM_001004719
OR4M2
olfactory receptor, family 4, subfamily M, member 2
chr6_-_32227695 0.387 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr10_-_45350804 0.386 NM_001002266
MARCH8
membrane-associated ring finger (C3HC4) 8
chr4_+_95595419 0.379 PDLIM5
PDZ and LIM domain 5
chr4_-_140280031 0.376 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr11_-_57275828 0.376 NM_001145101
BTBD18
BTB (POZ) domain containing 18
chr6_-_32227645 0.371 PRRT1
proline-rich transmembrane protein 1
chr5_-_110090264 0.370 NM_001039763
TMEM232
transmembrane protein 232
chr6_+_31016755 0.364 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr2_-_157892391 0.364 NM_001009959
ERMN
ermin, ERM-like protein
chr10_+_114125003 0.362 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_-_90197140 0.361 NM_014883
FAM13A
family with sequence similarity 13, member A
chrX_-_135691168 0.360 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_+_47073029 0.358 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chrX_-_135690770 0.358 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr11_-_5247948 0.357 NM_005330
HBE1
hemoglobin, epsilon 1
chr10_-_50402148 0.355 NM_170753
PGBD3
piggyBac transposable element derived 3
chr6_+_43060304 0.354 PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr15_-_41300488 0.351 EPB42
erythrocyte membrane protein band 4.2
chr16_-_12805133 0.349 CPPED1
calcineurin-like phosphoesterase domain containing 1
chr9_+_124072947 0.346 NM_199177
MRRF
mitochondrial ribosome recycling factor
chr1_-_100416358 0.342 NM_144620
LRRC39
leucine rich repeat containing 39
chr22_+_16423147 0.341 NM_031481
SLC25A18
solute carrier family 25 (mitochondrial carrier), member 18
chr2_+_151922350 0.337 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_190811479 0.336 NM_002922
RGS1
regulator of G-protein signaling 1
chr6_+_88111289 0.331 NM_001010868
C6orf163
chromosome 6 open reading frame 163
chr10_-_72215116 0.326 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr14_+_77939845 0.325 NM_004796
NRXN3
neurexin 3
chr5_+_140194152 0.320 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr8_+_124263932 0.319 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr10_-_106083652 0.316 NM_033397
ITPRIP
inositol 1,4,5-triphosphate receptor interacting protein
chr3_-_50583425 0.313 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr8_+_9990471 0.311 NM_001135671
MSRA
methionine sulfoxide reductase A
chr15_-_91078307 0.311 FAM174B
family with sequence similarity 174, member B
chr8_-_7718769 0.306 NM_152250
NM_001040703
DEFB105A
DEFB105B
defensin, beta 105A
defensin, beta 105B
chr12_+_99391870 0.305 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_-_149004852 0.305 CTSS
cathepsin S
chr12_+_99391681 0.300 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chrX_+_153423652 0.298 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr6_-_109795925 0.297 CD164
CD164 molecule, sialomucin
chr5_+_67622242 0.292 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_56914668 0.290 NM_002728
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr3_-_180467483 0.286 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr11_-_117718532 0.285 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr1_+_51968191 0.284 OSBPL9
oxysterol binding protein-like 9
chr12_+_79362256 0.282 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr19_+_56958452 0.281 NM_001462
FPR2
formyl peptide receptor 2
chr18_+_70317802 0.279 NM_001168499
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr19_+_56990222 0.277 NM_002030
FPR3
formyl peptide receptor 3
chr11_-_51269023 0.272 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr4_+_71261066 0.266 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr3_-_46761248 0.266 NM_199183
PRSS45
protease, serine, 45
chr3_+_142175329 0.265 SLC25A36
solute carrier family 25, member 36
chr13_+_94883853 0.265 NM_001160100
NM_182848
CLDN10

claudin 10

chr1_+_2927905 0.265 NM_080431
ACTRT2
actin-related protein T2
chr7_-_16471817 0.263 NM_015464
SOSTDC1
sclerostin domain containing 1
chr15_+_83467295 0.260 PDE8A
phosphodiesterase 8A
chr18_-_53438854 0.258


chr9_-_35804997 0.256 HINT2
histidine triad nucleotide binding protein 2
chr14_-_20969706 0.255 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr17_+_63338500 0.254 BPTF
bromodomain PHD finger transcription factor
chr17_+_38306339 0.253 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr14_-_20694023 0.250 NM_001004731
OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr8_+_92184022 0.248 NM_001129890
LRRC69
leucine rich repeat containing 69
chr7_+_94953148 0.247 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr1_+_171871283 0.246 NM_001195190
LOC730159
hypothetical protein LOC730159
chr5_-_126394338 0.246 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chr11_+_54867202 0.245 NM_001005274
OR4A16
olfactory receptor, family 4, subfamily A, member 16
chr11_-_123758448 0.245 NM_001005468
OR8B2
olfactory receptor, family 8, subfamily B, member 2
chr6_-_11490487 0.242 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr9_-_103237851 0.242 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr11_-_30910074 0.241 NM_020869
DCDC5
doublecortin domain containing 5
chr6_+_31698447 0.239


chr13_+_45174446 0.239 NM_152719
SPERT
spermatid associated
chr7_-_107667728 0.238 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr11_-_62231636 0.237 NM_001122955
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_+_92330691 0.237 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr2_-_39310176 0.234 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr12_+_6424293 0.234 NM_001242
CD27
CD27 molecule
chr2_-_169596078 0.233 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr17_-_35327318 0.231 NM_018530
GSDMB
gasdermin B
chr1_-_144793989 0.228 NM_183372
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chr6_+_37895244 0.228 NM_021943
ZFAND3
zinc finger, AN1-type domain 3
chr11_+_5431213 0.227 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr12_-_10479810 0.224 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr7_-_133652042 0.223 SLC35B4
solute carrier family 35, member B4
chr11_+_59027624 0.223 NM_001004706
OR4D11
olfactory receptor, family 4, subfamily D, member 11
chr10_-_921694 0.220 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr2_+_169631777 0.220 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_+_12401214 0.220 NM_058169
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr16_+_33168191 0.217 NM_001099687
TP53TG3B
TP53 target 3B
chr14_-_106352471 0.217


chr1_-_23568854 0.215 NM_001077195
ZNF436
zinc finger protein 436
chr7_+_77307382 0.215 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr2_+_143351536 0.214 NM_001032998
NM_003937
KYNU

kynureninase

chr6_+_28601767 0.213 NM_001509
NM_003996
GPX5

glutathione peroxidase 5 (epididymal androgen-related protein)

chr5_-_135318420 0.207 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr6_-_27988152 0.206 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr1_+_190394214 0.206 NM_130782
RGS18
regulator of G-protein signaling 18
chr11_+_59612712 0.204 NM_000139
MS4A2
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
chr10_+_97505398 0.200 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr19_-_14813688 0.199 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr1_+_172683834 0.198 NM_005684
GPR52
G protein-coupled receptor 52
chr6_+_88026338 0.198 ZNF292
zinc finger protein 292
chr3_+_63859114 0.194 NM_001177387
ATXN7
ataxin 7
chr18_+_13815542 0.193 NM_005913
MC5R
melanocortin 5 receptor
chr5_+_162862808 0.193 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr6_+_158653679 0.191 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr1_-_159099090 0.188 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr11_-_5178505 0.186 NM_001004760
OR51V1
olfactory receptor, family 51, subfamily V, member 1
chr1_-_172153087 0.183 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_+_33151703 0.182 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr10_-_50012058 0.182 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr7_+_143331954 0.181 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.33 5.01e-07 GO:0007608 sensory perception of smell
3.15 7.43e-07 GO:0007606 sensory perception of chemical stimulus
1.31 1.16e-03 GO:0050896 response to stimulus
1.71 4.97e-03 GO:0003008 system process
2.01 1.89e-02 GO:0007600 sensory perception
4.42 2.05e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
4.25 3.06e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.46 9.55e-06 GO:0071944 cell periphery
1.47 1.14e-05 GO:0005886 plasma membrane
1.26 2.87e-02 GO:0016021 integral to membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.49 3.05e-08 GO:0004984 olfactory receptor activity
2.15 1.99e-07 GO:0004888 transmembrane receptor activity
2.41 1.13e-06 GO:0004930 G-protein coupled receptor activity
1.90 1.93e-06 GO:0004872 receptor activity
1.69 9.07e-05 GO:0004871 signal transducer activity
1.69 9.07e-05 GO:0060089 molecular transducer activity