Motif ID: HNF1A.p2

Z-value: 6.701


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF1Achr12_+_1199009310.997.4e-13Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_24491498 36.117 NM_001195610
DCDC2
doublecortin domain containing 2
chr7_-_44547382 24.267 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr20_+_42417752 22.538 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr20_+_41621119 22.482 SGK2
serum/glucocorticoid regulated kinase 2
chr12_-_15757114 22.344 EPS8
epidermal growth factor receptor pathway substrate 8
chr4_-_977163 22.191 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr20_+_41621079 21.997 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr16_-_86527608 21.155 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr14_-_93924663 20.631 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr7_+_45894480 20.494 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chrX_-_105169370 20.291 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_+_175908948 20.193 NM_017675
CDHR2
cadherin-related family member 2
chr14_-_93829113 20.123 NM_016186
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_93829309 19.378 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr17_-_61655915 19.310 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_-_40995606 19.233 PRODH2
proline dehydrogenase (oxidase) 2
chr20_+_42463419 19.189 HNF4A
hepatocyte nuclear factor 4, alpha
chr1_+_48460943 19.176 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr20_+_42417502 19.000 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_+_11211282 18.773 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr21_-_46399900 18.691 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr7_-_47545717 18.687 NM_022748
TNS3
tensin 3
chr14_-_93829347 18.646 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_74520796 18.607 NM_001134
AFP
alpha-fetoprotein
chr1_+_17779528 18.309 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_-_40995564 18.201 PRODH2
proline dehydrogenase (oxidase) 2
chr14_-_93924873 17.513 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_-_17797127 17.438 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr20_+_42463387 17.271 HNF4A
hepatocyte nuclear factor 4, alpha
chr7_-_50600536 17.138 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr2_+_27573206 17.137 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr20_+_42463350 16.857 HNF4A
hepatocyte nuclear factor 4, alpha
chr4_-_69852090 16.608 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr14_+_38772870 16.142 NM_054024
MIA2
melanoma inhibitory activity 2
chr17_+_71065478 16.119 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr17_+_38306339 15.943 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr10_+_101532450 15.695 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_-_186970366 15.402 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr20_+_42463279 15.030 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr6_+_64289585 14.814 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr14_+_20226762 14.533 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr14_-_93859394 14.427 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr19_-_53081326 14.424 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr17_+_71154240 14.361 NM_001162997
LOC100130933
hypothetical protein LOC100130933
chr14_+_94097513 14.280 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr2_-_88208650 14.239 NM_001443
FABP1
fatty acid binding protein 1, liver
chr6_-_116488458 14.131 NM_002031
FRK
fyn-related kinase
chr4_-_155731288 14.015 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr11_+_46697345 13.858 F2
coagulation factor II (thrombin)
chr4_-_110942576 13.838 CFI
complement factor I
chr4_+_74488947 13.790 ALB
albumin
chr17_+_4638966 13.448 NM_001014985
GLTPD2
glycolipid transfer protein domain containing 2
chr8_+_76482661 13.348 HNF4G
hepatocyte nuclear factor 4, gamma
chr4_+_74488910 13.040 ALB
albumin
chr19_-_53081383 13.030 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr4_-_100359353 12.910 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr6_+_31731667 12.508 APOM
apolipoprotein M
chr16_+_21152516 12.505 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr11_+_46697335 12.476 F2
coagulation factor II (thrombin)
chr1_+_93830106 12.302 LOC100129046
hypothetical LOC100129046
chr6_+_31731647 12.237 NM_019101
APOM
apolipoprotein M
chr4_+_3413489 12.122 NM_001528
HGFAC
HGF activator
chr11_+_46697312 12.072 NM_000506
F2
coagulation factor II (thrombin)
chr12_+_54910767 11.981 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr4_+_74488835 11.926 NM_000477
ALB
albumin
chr15_+_56511466 11.772 NM_000236
LIPC
lipase, hepatic
chr10_-_52315436 11.663 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr10_-_52315390 11.428 A1CF
APOBEC1 complementation factor
chr10_+_101532544 11.129 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_+_3413457 11.021 HGFAC
HGF activator
chrX_+_70351812 10.724 GJB1
gap junction protein, beta 1, 32kDa
chr1_+_93830169 10.666 LOC100129046
hypothetical LOC100129046
chr11_-_117200618 10.597 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr8_+_21967008 10.333 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr10_+_99334411 10.196 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr10_+_114144512 10.022 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_-_67943157 9.980 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chrX_+_70351773 9.791 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chr4_-_110942783 9.586 NM_000204
CFI
complement factor I
chr6_+_167624792 9.483 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr4_+_187424111 9.480 NM_000128
F11
coagulation factor XI
chr17_-_202557 9.392 RPH3AL
rabphilin 3A-like (without C2 domains)
chr5_+_73145098 9.387 RGNEF
190 kDa guanine nucleotide exchange factor
chr9_-_122852356 9.229 NM_001735
C5
complement component 5
chr17_+_1592879 8.739 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr10_+_99334069 8.702 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr15_-_88150823 8.400 ANPEP
alanyl (membrane) aminopeptidase
chr1_-_202449659 8.065 NM_198447
GOLT1A
golgi transport 1A
chr16_-_46826588 7.934 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr1_-_20014180 7.752 NM_019062
RNF186
ring finger protein 186
chr1_+_18680010 7.565 NM_152375
KLHDC7A
kelch domain containing 7A
chr11_-_64582568 7.474 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr17_+_1592893 7.436 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr5_-_138746840 7.366 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr1_-_204455269 7.346 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr19_-_63556632 7.332 NM_130786
A1BG
alpha-1-B glycoprotein
chr6_-_26038817 7.311 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr17_-_202617 7.244 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr17_+_1586034 7.121 WDR81
WD repeat domain 81
chr5_-_138746917 7.098 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr22_-_36836478 7.085 BAIAP2L2
BAI1-associated protein 2-like 2
chr4_+_74497998 6.769 ALB
albumin
chr22_-_36836620 6.679 NM_025045
BAIAP2L2
BAI1-associated protein 2-like 2
chr12_+_119900677 6.538 HNF1A
HNF1 homeobox A
chr18_+_27425727 5.873 NM_000371
TTR
transthyretin
chr10_-_101680645 5.843 DNMBP
dynamin binding protein
chr4_+_74498042 5.708 ALB
albumin
chr4_+_74566325 5.631 NM_001133
AFM
afamin
chr20_+_61841553 5.614 NM_020062
SLC2A4RG
SLC2A4 regulator
chr1_+_205328834 5.612 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr6_+_167456230 5.581 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr4_+_187424336 5.440 F11
coagulation factor XI
chr14_+_87560646 5.231 LOC283587
hypothetical protein LOC283587
chr10_+_5126613 5.160 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126589 5.127 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_+_1593040 5.035 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr4_+_69996780 4.931 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr7_-_156494741 4.823 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr10_+_5126556 4.816 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_-_38052481 4.763 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr7_+_139175420 4.708 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr16_-_65510230 4.514 NM_004062
CDH16
cadherin 16, KSP-cadherin
chr11_+_64079665 4.435 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr2_+_62787534 4.394 NM_001142614
EHBP1
EH domain binding protein 1
chr5_+_176446425 4.349 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr20_+_35406497 4.318 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr14_-_57030227 4.241 NM_018168
C14orf105
chromosome 14 open reading frame 105
chrX_-_131375217 4.223 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr1_-_228916559 4.146 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr19_-_40996040 3.781 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr20_-_43972061 3.661 PLTP
phospholipid transfer protein
chr16_-_20271530 3.464 NM_001008389
NM_003361
UMOD

uromodulin

chr2_-_168812132 3.456 NM_013233
STK39
serine threonine kinase 39
chr6_+_161043214 3.441 NM_000301
NM_001168338
PLG

plasminogen

chr4_+_74493918 3.324 ALB
albumin
chr11_-_62539857 3.314 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr2_+_101981888 3.276 NM_173343
IL1R2
interleukin 1 receptor, type II
chr19_+_50109416 3.103 APOC1
apolipoprotein C-I
chr3_+_63928459 3.073 NM_001128149
ATXN7
ataxin 7
chr20_-_7869068 3.056 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_-_107569256 2.991 NM_001847
COL4A6
collagen, type IV, alpha 6
chr12_+_119900931 2.919 NM_000545
HNF1A
HNF1 homeobox A
chr3_+_150675117 2.912 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr3_-_162572441 2.844 NM_001040100
C3orf57
chromosome 3 open reading frame 57
chr4_+_155703581 2.766 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chrX_+_107569671 2.701 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr11_-_118405288 2.666 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr8_-_124818754 2.646 NM_001003954
NM_004306
ANXA13

annexin A13

chr16_+_88224276 2.629 DPEP1
dipeptidase 1 (renal)
chr7_+_94953148 2.506 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr5_+_140509803 2.500 NM_018939
PCDHB6
protocadherin beta 6
chr7_-_27133163 2.426 NM_153631
HOXA3
homeobox A3
chr4_+_154345039 2.393 NM_015271
TRIM2
tripartite motif containing 2
chr6_-_31789824 2.320


chr16_+_30118036 2.266 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr17_-_53335748 2.252 NM_017949
CUEDC1
CUE domain containing 1
chr6_-_52736231 2.231 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr16_-_56389176 2.193 NM_001130099
KIFC3
kinesin family member C3
chr17_+_56832255 2.182 TBX2
T-box 2
chr13_-_99983945 2.134 NM_033110
A2LD1
AIG2-like domain 1
chr1_-_228916486 2.098 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr11_+_551449 2.080 NM_001143994
NM_003475
RASSF7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr14_+_38805251 2.079 NM_203356
CTAGE5
CTAGE family, member 5
chr6_-_52060327 2.056 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr20_-_17589122 2.053 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr20_+_55569542 2.024 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_-_36562341 1.991 NM_018166
FAM176B
family with sequence similarity 176, member B
chr3_+_150675169 1.973 TM4SF4
transmembrane 4 L six family member 4
chr17_+_65009986 1.907 MAP2K6
mitogen-activated protein kinase kinase 6
chr1_-_228916470 1.905 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_+_20682812 1.843 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr9_-_116305273 1.810 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr3_-_25654659 1.809 TOP2B
topoisomerase (DNA) II beta 180kDa
chr6_-_29120930 1.796 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr12_-_23993830 1.748 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr10_+_111755715 1.725 NM_019903
ADD3
adducin 3 (gamma)
chr2_+_101874809 1.721 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_+_205344200 1.679 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr2_-_162638790 1.637 DPP4
dipeptidyl-peptidase 4
chr16_+_56286212 1.637 NM_032269
CCDC135
coiled-coil domain containing 135
chr7_+_99263571 1.632 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr4_-_159312973 1.561 FAM198B
family with sequence similarity 198, member B
chr4_+_56731117 1.531 NM_020722
KIAA1211
KIAA1211
chr7_+_129913271 1.522 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr7_-_83108682 1.508 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr22_-_41685827 1.506 NM_001184971
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr9_-_115901157 1.488 NM_138424
KIF12
kinesin family member 12
chr2_-_162639297 1.479 NM_001935
DPP4
dipeptidyl-peptidase 4
chr9_-_33385265 1.425 AQP7
aquaporin 7
chr6_-_133008834 1.422 NM_138327
TAAR1
trace amine associated receptor 1
chr22_+_29696662 1.345


chr20_+_31713750 1.324 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr2_+_108271526 1.303 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr5_+_67622242 1.288 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_+_124537334 1.284 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_+_97696462 1.260 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr1_+_20353284 1.251


chr3_+_185430910 1.238 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr6_-_25982418 1.235 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr1_-_42402973 1.230 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.50 1.43e-04 GO:0071702 organic substance transport
2.74 4.79e-04 GO:0006082 organic acid metabolic process
26.06 8.03e-04 GO:0046415 urate metabolic process
23.89 1.36e-03 GO:0051917 regulation of fibrinolysis
1.80 2.18e-03 GO:0042221 response to chemical stimulus
5.18 4.52e-03 GO:0006805 xenobiotic metabolic process
5.18 4.52e-03 GO:0071466 cellular response to xenobiotic stimulus
5.14 4.88e-03 GO:0009410 response to xenobiotic stimulus
10.03 6.32e-03 GO:0030301 cholesterol transport
9.79 7.51e-03 GO:0015918 sterol transport
12.29 8.86e-03 GO:0030195 negative regulation of blood coagulation
11.86 1.10e-02 GO:0050819 negative regulation of coagulation
25.48 1.29e-02 GO:0051918 negative regulation of fibrinolysis
15.09 1.80e-02 GO:0034381 plasma lipoprotein particle clearance
22.93 2.13e-02 GO:0019934 cGMP-mediated signaling
43.00 2.51e-02 GO:0015712 hexose phosphate transport
43.00 2.51e-02 GO:0015760 glucose-6-phosphate transport
6.85 2.53e-02 GO:0015711 organic anion transport
2.17 3.11e-02 GO:0006629 lipid metabolic process
4.25 3.38e-02 GO:0015849 organic acid transport
9.83 3.44e-02 GO:0097006 regulation of plasma lipoprotein particle levels
7.72 3.79e-02 GO:0048771 tissue remodeling
3.65 4.05e-02 GO:0008202 steroid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.17 1.07e-06 GO:0045177 apical part of cell
5.80 1.20e-06 GO:0016324 apical plasma membrane
2.67 2.47e-05 GO:0005615 extracellular space
2.24 5.58e-04 GO:0044421 extracellular region part
7.72 6.01e-03 GO:0031983 vesicle lumen
6.92 1.24e-02 GO:0031091 platelet alpha granule
1.99 1.28e-02 GO:0000267 cell fraction
2.17 1.52e-02 GO:0005624 membrane fraction
2.10 2.66e-02 GO:0005626 insoluble fraction
7.32 3.03e-02 GO:0031093 platelet alpha granule lumen
1.64 3.13e-02 GO:0005576 extracellular region
24.57 3.35e-02 GO:0005577 fibrinogen complex
7.17 3.41e-02 GO:0034774 secretory granule lumen
1.40 3.98e-02 GO:0005886 plasma membrane
1.60 4.02e-02 GO:0044459 plasma membrane part
1.39 4.17e-02 GO:0071944 cell periphery
6.88 4.29e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
19.11 1.20e-02 GO:0034185 apolipoprotein binding
15.29 3.18e-02 GO:0008514 organic anion transmembrane transporter activity
7.82 3.24e-02 GO:0043498 cell surface binding
5.21 4.48e-02 GO:0004867 serine-type endopeptidase inhibitor activity