Motif ID: HMGA1,2.p2

Z-value: 1.976


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGA2chr12_+_64504835-0.674.3e-03Click!
HMGA1chr6_+_343145450.391.4e-01Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_16471817 2.583 NM_015464
 SOSTDC1
sclerostin domain containing 1
chr10_+_89257569 2.191 NM_001178118
 MINPP1
multiple inositol-polyphosphate phosphatase 1
chr1_-_143708467 2.060 NM_001195260
 PDE4DIP
phosphodiesterase 4D interacting protein
chr4_+_75449720 1.999 NM_001432
 EREG
epiregulin
chr1_+_196874867 1.905 PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_+_77307382 1.881 NM_001127357
NM_001127359
NM_020432
 PHTF2


putative homeodomain transcription factor 2


chr1_-_158815850 1.873 CD84
CD84 molecule
chr1_-_158815895 1.816 NM_001184879
NM_001184881
NM_001184882
NM_003874
 CD84



CD84 molecule



chr1_+_194887630 1.790 NM_000186
NM_001014975
 CFH

complement factor H

chr1_-_205272619 1.790 NM_001083924
NM_023938
 C1orf116

chromosome 1 open reading frame 116

chr7_+_123036312 1.744 NM_080928
 ASB15
ankyrin repeat and SOCS box containing 15
chr1_+_239762179 1.743 NM_003679
 KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_+_159350850 1.731 NM_018342
 TMEM144
transmembrane protein 144
chr7_-_7724762 1.726 NM_002947
 RPA3
replication protein A3, 14kDa
chr1_+_234624266 1.716 NM_145861
 EDARADD
EDAR-associated death domain
chr4_+_170817787 1.714 CLCN3
chloride channel 3
chr1_+_196874759 1.684 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr7_-_112545840 1.671 LOC401397
hypothetical LOC401397
chr7_-_112545847 1.658 LOC401397
hypothetical LOC401397
chr1_+_196874839 1.652 PTPRC
protein tyrosine phosphatase, receptor type, C

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.25 1.37e-15 GO:0007608 sensory perception of smell
2.23 3.98e-17 GO:0007606 sensory perception of chemical stimulus
1.69 1.04e-09 GO:0007600 sensory perception
1.38 1.64e-04 GO:0050877 neurological system process
1.29 6.12e-03 GO:0003008 system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.49 3.15e-02 GO:0005544 calcium-dependent phospholipid binding
2.30 1.40e-16 GO:0004984 olfactory receptor activity
1.63 7.20e-09 GO:0004930 G-protein coupled receptor activity
1.33 2.93e-03 GO:0004888 transmembrane receptor activity
1.24 3.80e-02 GO:0004872 receptor activity