Motif ID: ZNF423.p2

Z-value: 2.788


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_484184180.523.7e-02Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_1992862 3.526 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr21_+_25856311 3.070 MIR155HG
MIR155 host gene (non-protein coding)
chr11_+_61352209 3.021 NM_004265
FADS2
fatty acid desaturase 2
chr15_+_62230962 2.989 NM_024798
SNX22
sorting nexin 22
chr19_-_1993022 2.977 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr11_+_61352348 2.828 FADS2
fatty acid desaturase 2
chr17_-_8711701 2.675 NM_001010855
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr16_-_87297525 2.595 NM_001171816
RNF166
ring finger protein 166
chr17_-_33178987 2.577 HNF1B
HNF1 homeobox B
chr17_+_73676219 2.575 NM_004710
SYNGR2
synaptogyrin 2
chr19_+_14405100 2.527 NM_002741
PKN1
protein kinase N1
chr19_-_10311262 2.517 NM_002162
ICAM3
intercellular adhesion molecule 3
chr1_-_27825178 2.476 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr19_+_18391423 2.459


chr7_+_101247601 2.392 NM_181552
CUX1
cut-like homeobox 1
chr19_-_4017739 2.340 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr17_-_45582872 2.304 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr16_+_84490267 2.206 NM_002163
IRF8
interferon regulatory factor 8
chr1_+_110031940 2.190 NM_000561
NM_146421
GSTM1

glutathione S-transferase mu 1

chr16_+_66236512 2.170 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr1_-_26517342 2.140 NM_145345
UBXN11
UBX domain protein 11
chr11_-_60819273 1.860 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr20_+_41978195 1.822 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr20_-_49592444 1.817 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr9_-_37024358 1.804 NM_016734
PAX5
paired box 5
chr6_+_33352886 1.762 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr21_-_45786709 1.755 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr19_+_11770360 1.746 NM_152356
ZNF491
zinc finger protein 491
chr16_+_66236559 1.741 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr7_+_149733309 1.733


chr1_-_210939820 1.701 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr19_+_12036513 1.690 NM_001136501
ZNF844
zinc finger protein 844
chr11_-_494887 1.679 RNH1
ribonuclease/angiogenin inhibitor 1
chr17_+_73638430 1.664 NM_152468
TMC8
transmembrane channel-like 8
chr19_+_14405216 1.630 PKN1
protein kinase N1
chr6_-_32268267 1.624 GPSM3
G-protein signaling modulator 3
chr8_+_145137354 1.618 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr1_+_110056386 1.594 NM_000851
GSTM5
glutathione S-transferase mu 5
chr3_-_52542748 1.580 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr7_-_5536783 1.561 ACTB
actin, beta
chr7_-_5536704 1.529 NM_001101
ACTB
actin, beta
chr19_-_11550765 1.517 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr9_-_130526192 1.512 NM_032799
ZDHHC12
zinc finger, DHHC-type containing 12
chr1_+_26517032 1.507 CD52
CD52 molecule
chr17_-_37681917 1.502 NM_012448
STAT5B
signal transducer and activator of transcription 5B
chr11_-_47356650 1.480 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr5_+_131774478 1.478 NM_001013717
C5orf56
chromosome 5 open reading frame 56
chr7_+_26158257 1.465 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr18_-_17538735 1.442 NM_138340
ABHD3
abhydrolase domain containing 3
chr3_-_13436725 1.441 NUP210
nucleoporin 210kDa
chr17_-_33179118 1.440 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr17_-_77488258 1.432 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr22_+_38183480 1.415 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_26517045 1.406 CD52
CD52 molecule
chr18_+_75261231 1.401 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr20_+_30103642 1.399 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chr3_-_52542849 1.390 NT5DC2
5'-nucleotidase domain containing 2
chr12_-_123914219 1.388 SCARB1
scavenger receptor class B, member 1
chr1_+_9634368 1.386 NM_005026
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide
chr20_+_61838479 1.381 LIME1
Lck interacting transmembrane adaptor 1
chr19_+_18391211 1.370 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr6_-_88932485 1.360 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr11_-_67028415 1.341 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr8_-_70908130 1.329 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr19_-_11550576 1.320 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr2_-_242449662 1.316 NM_005018
PDCD1
programmed cell death 1
chr17_+_1574583 1.306 NM_001163811
WDR81
WD repeat domain 81
chr17_+_34114924 1.298 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_11588525 1.295 LITAF
lipopolysaccharide-induced TNF factor
chr14_+_23907065 1.293 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr10_+_85923473 1.292 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr12_-_48387394 1.269 FMNL3
formin-like 3
chr9_+_92603920 1.253 SYK
spleen tyrosine kinase
chr19_-_55524445 1.243 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr6_+_31651319 1.227 NM_000594
TNF
tumor necrosis factor
chr2_+_218833982 1.222 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr3_-_16530132 1.209 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr9_+_99303639 1.207 NM_003275
TMOD1
tropomodulin 1
chr8_-_65873658 1.205 NM_004820
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr5_+_68824143 1.197 OCLN
occludin
chr11_-_47356642 1.192 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr5_-_175896829 1.191 NM_014901
RNF44
ring finger protein 44
chr22_+_35586950 1.185 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr2_-_120697382 1.185 TMEM185B
transmembrane protein 185B (pseudogene)
chr12_+_111829191 1.183 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr3_-_16529996 1.168 RFTN1
raftlin, lipid raft linker 1
chr2_-_120697148 1.166 TMEM185B
transmembrane protein 185B (pseudogene)
chr12_-_123914375 1.165 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr18_-_17538624 1.164 ABHD3
abhydrolase domain containing 3
chr1_-_210939727 1.163


chr11_-_431956 1.156 ANO9
anoctamin 9
chr10_-_134940315 1.151 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr2_-_120697441 1.147 TMEM185B
transmembrane protein 185B (pseudogene)
chr12_+_50071782 1.146 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr12_-_123914299 1.145 SCARB1
scavenger receptor class B, member 1
chr18_+_58341637 1.143 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr20_-_23014828 1.139 NM_012072
CD93
CD93 molecule
chr12_+_58276114 1.139 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr7_+_50314801 1.136 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr20_+_61838389 1.136 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr19_-_18409788 1.134 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr14_-_92651896 1.132 NM_001142593
NM_001142594
NM_014216
ITPK1


inositol 1,3,4-triphosphate 5/6 kinase


chr19_+_14108974 1.130


chr11_-_47356672 1.127 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr6_+_34312667 1.123 HMGA1
high mobility group AT-hook 1
chr17_+_70244945 1.121 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr1_-_183210296 1.111 NM_052966
FAM129A
family with sequence similarity 129, member A
chr18_-_11138760 1.107 NM_022068
FAM38B
family with sequence similarity 38, member B
chr11_+_65781322 1.105 NM_001134775
KLC2
kinesin light chain 2
chr11_-_60819110 1.104 VWCE
von Willebrand factor C and EGF domains
chr14_-_67051773 1.097 NM_182526
TMEM229B
transmembrane protein 229B
chr11_+_1925162 1.088 MRPL23
mitochondrial ribosomal protein L23
chr1_+_26516967 1.081 NM_001803
CD52
CD52 molecule
chr17_-_24918052 1.080 NM_198147
ABHD15
abhydrolase domain containing 15
chr11_-_431995 1.071 NM_001012302
ANO9
anoctamin 9
chr19_-_46550788 1.069 TGFB1
transforming growth factor, beta 1
chr20_-_23350038 1.061 NM_022080
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chr9_+_92604025 1.061 NM_001174168
SYK
spleen tyrosine kinase
chr17_-_37681837 1.060 STAT5B
signal transducer and activator of transcription 5B
chr1_-_85235210 1.055 NM_153259
MCOLN2
mucolipin 2
chr16_+_55950195 1.047 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr20_-_57015547 1.046 CTSZ
cathepsin Z
chr7_-_1034453 1.030 C7orf50
chromosome 7 open reading frame 50
chr9_+_92603894 1.028 SYK
spleen tyrosine kinase
chr1_+_110000396 1.027 GSTM2
GSTM4
glutathione S-transferase mu 2 (muscle)
glutathione S-transferase mu 4
chr1_-_210939929 1.026 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr9_+_92603884 1.026 SYK
spleen tyrosine kinase
chr11_+_1925075 1.019 NM_021134
MRPL23
mitochondrial ribosomal protein L23
chr20_+_61654816 1.010 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr11_-_66877519 1.008 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr19_-_1997229 1.005 MKNK2
MAP kinase interacting serine/threonine kinase 2
chrX_-_48713194 1.002 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_183210155 1.002 FAM129A
family with sequence similarity 129, member A
chr19_-_6410735 0.997 NM_024103
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr19_+_4591028 0.981 NM_001167942
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr18_-_5533967 0.981 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr22_+_38183262 0.979 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr6_-_3172775 0.977 NM_178012
TUBB2B
tubulin, beta 2B
chr17_-_18848713 0.973 NM_001039999
FAM83G
family with sequence similarity 83, member G
chr12_-_48387459 0.973 NM_175736
NM_198900
FMNL3

formin-like 3

chr20_-_57015698 0.969 NM_001336
CTSZ
cathepsin Z
chr19_+_1158129 0.961 EFNA2
ephrin-A2
chr19_-_1989937 0.951 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr9_+_135233047 0.951 NM_153710
C9orf96
chromosome 9 open reading frame 96
chr1_+_149521364 0.938 NM_020832
ZNF687
zinc finger protein 687
chr16_+_2807164 0.935 NM_006799
NM_144956
NM_144957
PRSS21


protease, serine, 21 (testisin)


chr12_+_63504618 0.932 NM_015279
TBC1D30
TBC1 domain family, member 30
chr22_-_22440054 0.922 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr12_+_63504708 0.920 TBC1D30
TBC1 domain family, member 30
chr10_+_26767698 0.919 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_-_10137626 0.919 CYS1
cystin 1
chr2_-_42574587 0.918 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr18_+_2896178 0.915 EMILIN2
elastin microfibril interfacer 2
chr17_+_25730048 0.915 CPD
carboxypeptidase D
chr20_-_30636535 0.914 LOC284804
hypothetical protein LOC284804
chr17_+_77783432 0.911 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr1_-_2333800 0.911 PEX10
peroxisomal biogenesis factor 10
chr17_-_35017650 0.906 NEUROD2
neurogenic differentiation 2
chr22_+_35639564 0.902 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_+_190753833 0.901 NM_001042519
NM_032321
C2orf88

chromosome 2 open reading frame 88

chr11_-_47356479 0.899 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr11_+_14621914 0.897 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr1_-_35431329 0.897 NM_005066
SFPQ
splicing factor proline/glutamine-rich
chr12_+_111829121 0.896 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr1_-_35431318 0.895 SFPQ
splicing factor proline/glutamine-rich
chr10_+_26767657 0.894 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr17_-_2187427 0.888 NM_018128
TSR1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
chrX_+_9392980 0.887 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr9_+_135232937 0.880 C9orf96
chromosome 9 open reading frame 96
chr7_-_139987044 0.879 DENND2A
DENN/MADD domain containing 2A
chr9_-_129782624 0.879 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr1_-_2333863 0.878 NM_002617
NM_153818
PEX10

peroxisomal biogenesis factor 10

chr18_+_2836979 0.876 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr14_+_23508922 0.875 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr6_+_27215039 0.871 NM_003495
HIST1H4I
histone cluster 1, H4i
chr6_-_32268615 0.870 GPSM3
G-protein signaling modulator 3
chr19_-_23733411 0.867 NM_138286
ZNF681
zinc finger protein 681
chr6_+_31538934 0.866 NM_006674
HCP5
HLA complex P5
chr19_+_1358664 0.866 DAZAP1
DAZ associated protein 1
chr19_-_52307642 0.865


chr19_-_5573725 0.861 SAFB2
scaffold attachment factor B2
chr17_-_70690664 0.859 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr16_-_30453646 0.858 NM_023931
ZNF747
zinc finger protein 747
chr16_+_31027249 0.858 BCKDK
branched chain ketoacid dehydrogenase kinase
chr1_+_945399 0.856


chr22_+_48740432 0.855 PIM3
pim-3 oncogene
chr20_-_62181588 0.848 NM_001039467
RGS19
regulator of G-protein signaling 19
chr17_-_20886680 0.842 NM_015276
USP22
ubiquitin specific peptidase 22
chr11_-_14621738 0.838 NM_148976
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr8_+_144711619 0.838 NM_024736
GSDMD
gasdermin D
chr19_+_54996613 0.833


chr15_-_81113676 0.827 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr11_+_14621884 0.824 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr11_+_14621844 0.822 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr8_-_22022757 0.818 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr17_+_43165608 0.814 NM_013351
TBX21
T-box 21
chr19_-_51081147 0.813 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr17_+_25730086 0.811 CPD
carboxypeptidase D
chr20_-_43972982 0.805 PLTP
phospholipid transfer protein
chr1_-_32574185 0.803 NM_023009
MARCKSL1
MARCKS-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 2.98e-04 GO:0065007 biological regulation
1.16 1.01e-03 GO:0050789 regulation of biological process
1.16 3.48e-03 GO:0050794 regulation of cellular process
1.22 1.56e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 2.75e-05 GO:0044424 intracellular part
1.10 3.73e-05 GO:0005622 intracellular
1.12 1.00e-03 GO:0043227 membrane-bounded organelle
1.12 1.38e-03 GO:0043231 intracellular membrane-bounded organelle
1.11 1.46e-03 GO:0043229 intracellular organelle
1.11 1.61e-03 GO:0043226 organelle
1.12 6.04e-03 GO:0005737 cytoplasm
1.05 1.05e-02 GO:0044464 cell part
1.05 1.08e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 4.74e-04 GO:0005515 protein binding
1.08 2.08e-03 GO:0005488 binding