Motif ID: CEBPA,B_DDIT3.p2

Z-value: 1.728


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CEBPAchr19_-_384852810.621.1e-02Click!
DDIT3chr12_-_562005470.322.2e-01Click!
CEBPBchr20_+_482407050.322.2e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_116125123 6.318 NM_000607
ORM1
orosomucoid 1
chr1_+_149221122 5.196 NM_003568
ANXA9
annexin A9
chr17_-_36346240 5.171 KRT23
keratin 23 (histone deacetylase inducible)
chr3_+_187813553 3.979 AHSG
alpha-2-HS-glycoprotein
chrX_+_9391314 3.969 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr3_+_187813538 3.847 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr6_+_32003380 3.838 C2
complement component 2
chr3_+_187813405 3.395 AHSG
alpha-2-HS-glycoprotein
chr6_+_32003180 3.192 NM_000063
NM_001145903
C2

complement component 2

chr6_+_167624792 2.951 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr12_-_120781002 2.425 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr4_-_9632192 2.370 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr14_-_22515725 2.273 JUB
jub, ajuba homolog (Xenopus laevis)
chr19_-_53950458 2.149 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr20_+_309938 2.043 TRIB3
tribbles homolog 3 (Drosophila)
chr9_+_80101810 2.015 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr9_-_129752687 1.976 NM_203305
FAM102A
family with sequence similarity 102, member A
chr20_+_309272 1.974 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr1_-_20122638 1.965 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr12_-_61615124 1.896 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_+_111571803 1.830 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr3_-_150422474 1.757 NM_000096
CP
ceruloplasmin (ferroxidase)
chr11_+_47236072 1.752 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr14_+_31868229 1.652 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_61655915 1.642 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr14_-_22516271 1.559 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr5_-_16791346 1.518 MYO10
myosin X
chr3_-_42818221 1.417


chr1_-_149611768 1.402 NM_003944
SELENBP1
selenium binding protein 1
chr12_+_99391870 1.371 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_-_55103938 1.331 DHCR24
24-dehydrocholesterol reductase
chr20_+_54420574 1.328 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr12_-_53153639 1.321 NM_144594
GTSF1
gametocyte specific factor 1
chr20_+_309675 1.267 TRIB3
tribbles homolog 3 (Drosophila)
chr17_+_71508581 1.249 NM_001258
CDK3
cyclin-dependent kinase 3
chr4_+_187424336 1.243 F11
coagulation factor XI
chr17_-_53847937 1.240 RNF43
ring finger protein 43
chr19_+_11211282 1.230 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr6_+_80397690 1.226 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr9_-_94095807 1.211 IARS
isoleucyl-tRNA synthetase
chr9_+_674193 1.205


chr6_+_132000134 1.203 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr9_-_94095787 1.190 NM_013417
IARS
isoleucyl-tRNA synthetase
chr15_+_80741876 1.188 LOC80154
hypothetical LOC80154
chr1_-_159543847 1.156 MPZ
myelin protein zero
chr13_+_51496679 1.155 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr17_+_1612056 1.117 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_85994788 1.108 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr17_-_36232366 1.101 NM_000421
KRT10
keratin 10
chr11_+_20000938 1.101 NAV2
neuron navigator 2
chr15_+_80741827 1.040 LOC80154
hypothetical LOC80154
chr8_+_82807218 1.040 NM_152284
CHMP4C
chromatin modifying protein 4C
chr16_-_30694799 1.037


chr9_-_94095810 1.025 NM_002161
IARS
isoleucyl-tRNA synthetase
chr17_-_45280377 0.973 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr3_-_49701085 0.963 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr11_+_62893836 0.959 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr2_+_108360798 0.953 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr16_-_28457728 0.949 NUPR1
nuclear protein, transcriptional regulator, 1
chr20_+_31613800 0.948 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr22_+_43451351 0.944 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr16_-_28457825 0.943 NM_001042483
NM_012385
NUPR1

nuclear protein, transcriptional regulator, 1

chr1_-_16006779 0.936 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr17_-_75427644 0.935 NM_003655
CBX4
chromobox homolog 4
chr1_+_99884018 0.914 NM_017734
PALMD
palmdelphin
chr1_+_17779528 0.896 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_158387975 0.891 NM_144699
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr20_+_32926452 0.879 ACSS2
acyl-CoA synthetase short-chain family member 2
chr9_-_122852356 0.878 NM_001735
C5
complement component 5
chr17_+_1612031 0.872 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_9570412 0.862 NM_198560
LHFPL4
lipoma HMGIC fusion partner-like 4
chr17_+_1612092 0.861 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_54910086 0.859 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr11_-_116168316 0.856 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr12_+_52105131 0.850 AMHR2
anti-Mullerian hormone receptor, type II
chr7_-_36991189 0.848 NM_001039459
ELMO1
engulfment and cell motility 1
chrX_-_15198509 0.838 NM_001168531
ASB9
ankyrin repeat and SOCS box containing 9
chr20_+_5935897 0.826 NM_001127458
CRLS1
cardiolipin synthase 1
chr1_-_143708467 0.824 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr22_+_21393107 0.789 IGLJ3
immunoglobulin lambda joining 3
chr1_+_26220895 0.774 EXTL1
exostoses (multiple)-like 1
chr11_-_69228286 0.774 NM_005117
FGF19
fibroblast growth factor 19
chrX_-_13745108 0.772 GPM6B
glycoprotein M6B
chr6_+_32021899 0.770 CFB
complement factor B
chr19_+_50144267 0.756 APOC2
apolipoprotein C-II
chr12_+_105519049 0.755 NM_002920
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr1_-_228916486 0.753 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_31117948 0.734 SDC3
syndecan 3
chr10_+_135010833 0.731 NM_001145201
NM_145202
PRAP1

proline-rich acidic protein 1

chr6_+_32021831 0.706 CFB
complement factor B
chr1_-_176205672 0.704 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr8_-_38127489 0.694 NM_000349
STAR
steroidogenic acute regulatory protein
chr6_-_24597717 0.689 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr17_-_77488258 0.683 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr11_-_8695974 0.682 ST5
suppression of tumorigenicity 5
chr14_+_34583863 0.672 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr11_+_59580630 0.651 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr11_+_2279932 0.628 TSPAN32
tetraspanin 32
chr8_+_124264054 0.624 FAM83A
family with sequence similarity 83, member A
chr3_+_1109619 0.623 NM_014461
CNTN6
contactin 6
chr1_-_228916470 0.616 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_40612891 0.616 NM_001198978
SMAP2
small ArfGAP2
chr2_+_37282516 0.613 LOC100505876
hypothetical LOC100505876
chr2_+_32244406 0.610 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr17_-_37599953 0.608 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr20_+_61842880 0.608 SLC2A4RG
SLC2A4 regulator
chrX_-_13745134 0.608 GPM6B
glycoprotein M6B
chr19_-_4253389 0.587 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr1_-_172153024 0.585 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_-_11887265 0.576 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr8_+_124263932 0.575 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr9_-_94095734 0.572 IARS
isoleucyl-tRNA synthetase
chr8_-_13018123 0.570 NM_001164271
DLC1
deleted in liver cancer 1
chr11_+_59580705 0.564 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr16_+_65552600 0.564 NM_001185177
NM_024922
CES3

carboxylesterase 3

chr4_+_184257337 0.560 NM_024949
WWC2
WW and C2 domain containing 2
chr15_+_80434362 0.556 UBE2Q2P2
ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr21_-_10120690 0.552 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr2_-_121964373 0.550 CLASP1
cytoplasmic linker associated protein 1
chr1_+_173111306 0.545 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr17_+_1611983 0.541 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr7_+_99263571 0.525 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr11_+_75106512 0.525 NM_025098
MOGAT2
monoacylglycerol O-acyltransferase 2
chr17_+_18588050 0.520 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1
chr6_-_157664464 0.514 C6orf35
chromosome 6 open reading frame 35
chr3_+_187917791 0.509 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr17_+_4621924 0.506 NM_003963
TM4SF5
transmembrane 4 L six family member 5
chr16_-_68880908 0.501 NM_001605
AARS
alanyl-tRNA synthetase
chr10_+_70650064 0.500 NM_025130
HKDC1
hexokinase domain containing 1
chr20_-_31055892 0.499 NM_080675
SUN5
Sad1 and UNC84 domain containing 5
chr5_-_24680841 0.496 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_+_159350850 0.494 NM_018342
TMEM144
transmembrane protein 144
chr5_+_75734759 0.493 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr16_+_24174374 0.493 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr12_+_27740694 0.489 NM_001029874
REP15
RAB15 effector protein
chr6_+_28601767 0.487 NM_001509
NM_003996
GPX5

glutathione peroxidase 5 (epididymal androgen-related protein)

chr17_-_15463742 0.486 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr12_+_52121699 0.480 NM_001005354
NM_018457
PRR13

proline rich 13

chr6_-_31954745 0.474 SLC44A4
solute carrier family 44, member 4
chr1_-_57057956 0.456 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr7_-_83108682 0.449 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr16_-_66827449 0.449 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr1_+_559129 0.445


chr7_+_123083096 0.442 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr9_-_14076901 0.442 NFIB
nuclear factor I/B
chr11_-_16953135 0.442 RPL36A
ribosomal protein L36a
chr16_-_68880844 0.435 AARS
alanyl-tRNA synthetase
chr21_-_46428788 0.430 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr19_-_12858956 0.423 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr17_-_17426416 0.420 PEMT
phosphatidylethanolamine N-methyltransferase
chr8_-_110730183 0.417 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr1_+_45738442 0.415 NM_015506
MMACHC
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr20_-_5982617 0.408 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr7_-_91601972 0.405 NM_001146152
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr11_+_22646229 0.402 NM_177553
GAS2
growth arrest-specific 2
chrX_-_15198093 0.400 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr14_-_57133361 0.395 NM_001080455
SLC35F4
solute carrier family 35, member F4
chr17_-_27252863 0.389 UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr1_-_51660328 0.378 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr8_-_110726921 0.375 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr12_-_120220493 0.374 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr11_-_102081654 0.373 NM_022122
MMP27
matrix metallopeptidase 27
chr22_+_21079355 0.372


chr4_+_74499651 0.371 ALB
albumin
chr6_+_126282078 0.370 NCOA7
nuclear receptor coactivator 7
chr9_+_135994734 0.367 NM_052821
WDR5
WD repeat domain 5
chr2_-_21084911 0.365 APOB
apolipoprotein B (including Ag(x) antigen)
chr14_+_20493467 0.362 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr6_-_11219932 0.361 NM_207582
ERVFRDE1
HERV-FRD provirus ancestral Env polyprotein
chr7_-_91601613 0.359 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr2_-_37150876 0.357 HEATR5B
HEAT repeat containing 5B
chr7_-_156494741 0.355 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr6_+_7524691 0.348 DSP
desmoplakin
chr4_+_187424111 0.344 NM_000128
F11
coagulation factor XI
chr19_-_57924946 0.344 NM_030972
ZNF611
zinc finger protein 611
chr1_+_234748187 0.339 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr14_-_22496098 0.336 NM_001166269
NM_001166270
NM_017815
HAUS4


HAUS augmin-like complex, subunit 4


chr7_+_29569913 0.334 NM_175887
PRR15
proline rich 15
chr15_+_56511466 0.334 NM_000236
LIPC
lipase, hepatic
chr11_-_118693021 0.334 NM_006500
MCAM
melanoma cell adhesion molecule
chr20_-_35318690 0.332 NM_001184731
NM_021081
GHRH

growth hormone releasing hormone

chr14_+_23508922 0.331 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr7_-_92686773 0.330 NM_198151
HEPACAM2
HEPACAM family member 2
chr17_-_77498399 0.325 NM_001145113
MYADML2
myeloid-associated differentiation marker-like 2
chr5_-_150264622 0.322 ZNF300
zinc finger protein 300
chr19_+_1401208 0.317 APC2
adenomatosis polyposis coli 2
chr2_-_158439868 0.315 NM_001105
ACVR1
activin A receptor, type I
chr20_+_57199469 0.313 NM_178457
ZNF831
zinc finger protein 831
chr6_+_131936057 0.312 NM_000045
ARG1
arginase, liver
chr16_-_88604029 0.310 NM_024043
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr19_-_56564068 0.306 NM_152353
CLDND2
claudin domain containing 2
chr5_-_176769094 0.305 F12
coagulation factor XII (Hageman factor)
chr1_+_26376611 0.304 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr5_-_150264583 0.303 ZNF300
zinc finger protein 300
chr8_+_110443881 0.299 NM_177531
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chrX_+_96025562 0.298 NM_013347
RPA4
replication protein A4, 30kDa
chr6_+_31604717 0.298 NM_001011700
MCCD1
mitochondrial coiled-coil domain 1
chr11_+_4564596 0.294 NM_001005170
OR52I2
olfactory receptor, family 52, subfamily I, member 2
chr19_+_41872141 0.294 NM_152603
ZNF567
zinc finger protein 567
chr1_-_180822686 0.293 NM_021133
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
14.48 2.01e-02 GO:0045723 positive regulation of fatty acid biosynthetic process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
34.75 9.59e-03 GO:0060230 lipoprotein lipase activator activity