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• Activity deltas table
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Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.381

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_159459814	3.846		APOA2	apolipoprotein A-II
chr1_-_159459999	3.763	NM_001643	APOA2	apolipoprotein A-II
chr12_-_51629874	3.193		KRT8	keratin 8
chr17_+_69939130	3.121	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr14_-_20562962	2.884	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr1_-_47468029	2.742	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr22_+_19458378	2.642	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_-_42847716	2.397	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr17_-_7023283	2.384		ASGR1	asialoglycoprotein receptor 1
chr7_+_134483305	2.230	NM_018295	TMEM140	transmembrane protein 140
chr20_-_45410033	2.129		ZMYND8	zinc finger, MYND-type containing 8
chr13_+_49658016	2.086
chr11_-_117589283	1.932	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr2_-_233586145	1.848		NGEF	neuronal guanine nucleotide exchange factor
chr2_-_233586164	1.736	NM_019850	NGEF	neuronal guanine nucleotide exchange factor
chr12_+_119900931	1.727	NM_000545	HNF1A	HNF1 homeobox A
chr17_-_7023378	1.673	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr12_+_119900677	1.668		HNF1A	HNF1 homeobox A
chr12_-_101835026	1.665		PAH	phenylalanine hydroxylase
chr6_-_41823056	1.582	NM_001166424 NM_002630	PGC	progastricsin (pepsinogen C)
chr13_-_45654292	1.581		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr4_+_100714995	1.572		MTTP	microsomal triglyceride transfer protein
chr1_-_167822248	1.571		F5	coagulation factor V (proaccelerin, labile factor)
chr15_-_32398220	1.570	NM_005135	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr1_+_116455898	1.536	NM_152367	MAB21L3	mab-21-like 3 (C. elegans)
chr16_-_11282595	1.527	NM_002761	PRM1	protamine 1
chr13_-_45654327	1.477	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr14_+_104337923	1.467	NM_001137601	ZBTB42	zinc finger and BTB domain containing 42
chr13_-_45654296	1.464		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_53081326	1.445		SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr10_-_91395194	1.432	NM_148977	PANK1	pantothenate kinase 1
chr14_+_31868229	1.405	NM_004274	AKAP6	A kinase (PRKA) anchor protein 6
chr1_-_1346465	1.403	NM_001145210	LOC441869	hypothetical protein LOC441869
chr2_-_43919392	1.388	NM_022436	ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5
chr6_-_138862271	1.384	NM_001144060	NHSL1	NHS-like 1
chr14_+_104338423	1.356		ZBTB42	zinc finger and BTB domain containing 42
chr10_-_69267774	1.351	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr8_-_30121741	1.343	NM_001100916	MBOAT4	membrane bound O-acyltransferase domain containing 4
chr6_-_138862273	1.334
chr1_-_167822334	1.320	NM_000130	F5	coagulation factor V (proaccelerin, labile factor)
chr7_+_106292975	1.275		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_-_165133239	1.263		GRB14	growth factor receptor-bound protein 14
chr7_+_50318801	1.248		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr3_+_173043832	1.242	NM_001164436	TMEM212	transmembrane protein 212
chr10_-_52315390	1.203		A1CF	APOBEC1 complementation factor
chr22_-_35835548	1.198		TMPRSS6	transmembrane protease, serine 6
chr16_-_66590856	1.195	NM_022355	DPEP2	dipeptidase 2
chr6_+_32003180	1.190	NM_000063 NM_001145903	C2	complement component 2
chr1_+_40635058	1.173	NM_001198980	SMAP2	small ArfGAP2
chr2_+_143351695	1.165		KYNU	kynureninase
chr18_+_53863865	1.158		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_32344192	1.157	NM_021209	NLRC4	NLR family, CARD domain containing 4
chr2_+_169637255	1.154	NM_001142270	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr19_+_17723285	1.137	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr12_-_61615124	1.135		PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_74488910	1.123		ALB	albumin
chr6_-_31740466	1.111		GPANK1	G patch domain and ankyrin repeats 1
chr10_-_5035967	1.078	NM_001135241	AKR1C1 AKR1C2	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr4_+_74488835	1.077	NM_000477	ALB	albumin
chr8_-_110724594	1.076	NM_001099756	SYBU	syntabulin (syntaxin-interacting)
chr4_-_176971175	1.076	NM_201591	GPM6A	glycoprotein M6A
chr12_-_69837831	1.074		TSPAN8	tetraspanin 8
chr3_-_10522267	1.070	NM_001001331 NM_001683	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr20_-_22514092	1.064	NM_153675	FOXA2	forkhead box A2
chr6_+_64289585	1.063		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr1_-_57204208	1.045	NM_000066	C8B	complement component 8, beta polypeptide
chr17_+_64922420	1.038	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr10_+_60606352	1.038	NM_032439	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_-_85622366	1.037	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr7_+_106293112	1.028	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr5_+_154072654	1.021	NM_015315	LARP1	La ribonucleoprotein domain family, member 1
chr10_-_52315436	1.015	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr7_-_140270749	1.010	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr6_-_26038817	0.984	NM_005835	SLC17A2	solute carrier family 17 (sodium phosphate), member 2
chr2_+_161980865	0.965	NM_006593	TBR1	T-box, brain, 1
chr7_+_111850367	0.962	NM_001007245 NM_001197080	IFRD1	interferon-related developmental regulator 1
chr2_+_201756048	0.944		CASP10	caspase 10, apoptosis-related cysteine peptidase
chr2_-_21084077	0.941		APOB	apolipoprotein B (including Ag(x) antigen)
chr1_-_205161821	0.926	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr17_+_70244945	0.925	NM_001006638 NM_001163990	RAB37	RAB37, member RAS oncogene family
chrX_+_70232362	0.924	NM_001170931 NM_005938	FOXO4	forkhead box O4
chr2_+_143351536	0.922	NM_001032998 NM_003937	KYNU	kynureninase
chr4_+_39084867	0.919	NM_175737	KLB	klotho beta
chr3_-_10522340	0.900		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr6_+_154373323	0.896	NM_001145279 NM_001145280 NM_001145281	OPRM1	opioid receptor, mu 1
chr17_-_36418869	0.892	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr10_+_4995597	0.890		AKR1C1 AKR1C3	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr9_+_135276940	0.887	NM_139025 NM_139026 NM_139027	ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr10_+_4995453	0.884	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chrX_-_153698930	0.884		HMGN1P37	high-mobility group nucleosome binding domain 1 pseudogene 37
chr10_-_50066386	0.883	NM_001010863	C10orf128	chromosome 10 open reading frame 128
chr6_+_32230172	0.883		PPT2	palmitoyl-protein thioesterase 2
chr7_-_25234582	0.876	NM_022150	NPVF	neuropeptide VF precursor
chr4_+_69716298	0.875	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_-_87156616	0.873		LOC285074	anaphase promoting complex subunit 1 pseudogene
chr17_-_23721485	0.869	NM_000638	VTN	vitronectin
chr6_+_32229599	0.868	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr4_+_22608252	0.860
chr12_-_94914133	0.857	NM_002108	HAL	histidine ammonia-lyase
chr18_-_50777634	0.852	NM_025214	CCDC68	coiled-coil domain containing 68
chr1_+_196874867	0.852		PTPRC	protein tyrosine phosphatase, receptor type, C
chr17_-_23721468	0.841		VTN	vitronectin
chr22_+_29696662	0.841
chr2_-_135498716	0.831	NM_001018046 NM_025052	YSK4	YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
chr6_+_44352443	0.826		TMEM151B	transmembrane protein 151B
chr2_+_86800940	0.824		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr13_-_48873735	0.818	NM_030925	CAB39L	calcium binding protein 39-like
chr10_+_102722275	0.817	NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr4_+_88939725	0.815	NM_004967	IBSP	integrin-binding sialoprotein
chr4_+_39084936	0.811		KLB	klotho beta
chr19_+_18357966	0.807	NM_004864	GDF15	growth differentiation factor 15
chr2_+_201755865	0.802	NM_001230 NM_032974 NM_032977	CASP10	caspase 10, apoptosis-related cysteine peptidase
chr2_+_176761552	0.801	NM_024501	HOXD1	homeobox D1
chr2_+_43919606	0.797	NM_022437	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8
chr4_-_123761615	0.795	NM_021803	IL21	interleukin 21
chr3_-_71376919	0.793		FOXP1	forkhead box P1
chr14_+_94148466	0.793	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr12_-_69838045	0.792	NM_004616	TSPAN8	tetraspanin 8
chr5_-_169657360	0.791		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr15_-_38387410	0.790	NM_004573	PLCB2	phospholipase C, beta 2
chr11_-_114880275	0.781	NM_001098517 NM_014333	CADM1	cell adhesion molecule 1
chr12_+_130004404	0.781	NM_198827	GPR133	G protein-coupled receptor 133
chr5_+_137701122	0.780	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr8_+_82807218	0.779	NM_152284	CHMP4C	chromatin modifying protein 4C
chr10_+_4995685	0.773		AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr19_-_51979838	0.768	NM_001145145	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr6_+_30238961	0.768	NM_033229	TRIM15	tripartite motif containing 15
chr6_+_112481970	0.766	NM_003880 NM_198239	WISP3	WNT1 inducible signaling pathway protein 3
chr4_-_186969041	0.762	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chrX_-_48578878	0.762	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr5_-_169657395	0.757	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr20_-_42561725	0.756
chr19_+_15612706	0.750	NM_000896	CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3
chr4_+_172971149	0.740	NM_001034845	GALNTL6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr5_+_171553780	0.737	NM_001171183	EFCAB9	EF-hand calcium binding domain 9
chr5_-_169657312	0.737		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_+_135277264	0.737		ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr6_-_50025115	0.733	NM_001166478	DEFB133	defensin, beta 133
chr14_-_22358752	0.728	NM_001126106	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr15_-_38387357	0.728		PLCB2	phospholipase C, beta 2
chr1_+_28134090	0.726	NM_001009568 NM_014474	SMPDL3B	sphingomyelin phosphodiesterase, acid-like 3B
chr9_-_115880494	0.723	NM_001633	AMBP	alpha-1-microglobulin/bikunin precursor
chr4_+_35962038	0.720	NM_001170700	DTHD1	death domain containing 1
chr17_-_43390108	0.719	NM_024320	PRR15L	proline rich 15-like
chr1_+_190811479	0.718	NM_002922	RGS1	regulator of G-protein signaling 1
chr2_-_180319013	0.716	NM_001113397	ZNF385B	zinc finger protein 385B
chr6_-_25834733	0.715	NM_170745	HIST1H2AA	histone cluster 1, H2aa
chr17_-_23721430	0.713		VTN	vitronectin
chr5_-_59819642	0.712	NM_001165899	PDE4D	phosphodiesterase 4D, cAMP-specific
chr5_-_169657192	0.709		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_144149794	0.708	NM_006472	TXNIP	thioredoxin interacting protein
chr1_-_24067347	0.701	NM_000147	FUCA1	fucosidase, alpha-L- 1, tissue
chr16_+_11346780	0.697	NM_152308	C16orf75	chromosome 16 open reading frame 75
chr9_-_205892	0.696	NM_152569	C9orf66	chromosome 9 open reading frame 66
chr18_+_30327341	0.694		DTNA	dystrobrevin, alpha
chr4_+_187424336	0.690		F11	coagulation factor XI
chrX_+_57329834	0.687	NM_174912	FAAH2	fatty acid amide hydrolase 2
chr17_-_23721420	0.685		VTN	vitronectin
chr7_+_149733309	0.685
chr9_-_115880366	0.682		AMBP	alpha-1-microglobulin/bikunin precursor
chr7_+_77307382	0.667	NM_001127357 NM_001127359 NM_020432	PHTF2	putative homeodomain transcription factor 2
chr17_+_38178969	0.662	NM_032353	VPS25	vacuolar protein sorting 25 homolog (S. cerevisiae)
chr17_-_23721351	0.661		VTN	vitronectin
chr1_+_198278339	0.658		NR5A2	nuclear receptor subfamily 5, group A, member 2
chr2_-_39201631	0.654		SOS1	son of sevenless homolog 1 (Drosophila)
chr17_+_69950782	0.654		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr15_-_38387164	0.653		PLCB2	phospholipase C, beta 2
chr11_+_22644732	0.645	NM_001143830	GAS2	growth arrest-specific 2
chr14_-_20636568	0.645	NM_016423	ZNF219	zinc finger protein 219
chr20_+_23293020	0.642	NM_022482	GZF1	GDNF-inducible zinc finger protein 1
chr9_-_115880281	0.638		AMBP	alpha-1-microglobulin/bikunin precursor
chr12_-_31370305	0.638		FAM60A	family with sequence similarity 60, member A
chr18_+_53170718	0.633	NM_015879	ST8SIA3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr5_+_147754467	0.631		FBXO38	F-box protein 38
chr2_+_86800898	0.631	NM_022780	RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_86801081	0.628		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr16_+_716936	0.616	NM_207112 NM_032304	HAGHL	hydroxyacylglutathione hydrolase-like
chr1_-_24342158	0.615	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chr10_-_54201400	0.615	NM_000242	MBL2	mannose-binding lectin (protein C) 2, soluble
chr11_-_116213511	0.605	NM_000039	APOA1	apolipoprotein A-I
chr17_-_73636386	0.604	NM_001127198	TMC6	transmembrane channel-like 6
chr4_+_187424111	0.598	NM_000128	F11	coagulation factor XI
chr17_+_75366524	0.597	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr1_-_31117948	0.593		SDC3	syndecan 3
chr6_+_32229771	0.590		PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr11_-_102331643	0.584	NM_002427	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr5_-_110090264	0.583	NM_001039763	TMEM232	transmembrane protein 232
chr11_-_16953135	0.582		RPL36A	ribosomal protein L36a
chr11_-_63690069	0.577	NM_014067	MACROD1	MACRO domain containing 1
chr18_+_30327243	0.576	NM_001198945 NM_001392 NM_032975 NM_032979	DTNA	dystrobrevin, alpha
chr4_-_38710376	0.570	NM_024943	TMEM156	transmembrane protein 156
chr16_+_11346812	0.569		C16orf75	chromosome 16 open reading frame 75
chr1_+_74473672	0.566	NM_015978	TNNI3K	TNNI3 interacting kinase
chr14_-_99140195	0.566	NM_001144995	CCDC85C	coiled-coil domain containing 85C
chr7_+_106292932	0.560		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_-_72151314	0.559	NM_018414	ST6GALNAC1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr10_+_70517863	0.558		SRGN	serglycin
chr12_-_31370351	0.555		FAM60A	family with sequence similarity 60, member A
chr12_+_77963563	0.552	NM_001135806	SYT1	synaptotagmin I
chr10_+_70517823	0.552	NM_002727	SRGN	serglycin

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
4.81	2.08e-02	GO:0002455	humoral immune response mediated by circulating immunoglobulin
4.55	3.77e-02	GO:0008206	bile acid metabolic process
4.94	4.12e-02	GO:0006958	complement activation, classical pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	6.24e-04	GO:0071944	cell periphery
1.26	6.30e-04	GO:0005886	plasma membrane
1.13	2.79e-02	GO:0016020	membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.37	6.84e-03	GO:0004871	signal transducer activity
1.37	6.84e-03	GO:0060089	molecular transducer activity
1.48	9.18e-03	GO:0004888	transmembrane receptor activity
1.40	1.15e-02	GO:0004872	receptor activity
1.59	1.16e-02	GO:0004930	G-protein coupled receptor activity