Motif ID: RXRA_VDR{dimer}.p2

Z-value: 1.524


Transcription factors associated with RXRA_VDR{dimer}.p2:

Gene SymbolEntrez IDGene Name
VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VDRchr12_-_46585032-0.552.9e-02Click!


Activity profile for motif RXRA_VDR{dimer}.p2.

activity profile for motif RXRA_VDR{dimer}.p2


Sorted Z-values histogram for motif RXRA_VDR{dimer}.p2

Sorted Z-values for motif RXRA_VDR{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRA_VDR{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_23742846 3.111 SPATA13
spermatogenesis associated 13
chr18_-_6404900 2.610 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr7_+_94374862 2.547 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr8_+_76482661 2.546 HNF4G
hepatocyte nuclear factor 4, gamma
chr21_-_46399900 2.435 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr10_+_102722275 2.245 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr15_+_89229275 2.125 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr19_-_7244876 1.863 NM_000208
NM_001079817
INSR

insulin receptor

chr22_+_48966394 1.593 TRABD
TraB domain containing
chr6_-_132314004 1.535 NM_001901
CTGF
connective tissue growth factor
chr22_+_16973556 1.514 TUBA8
tubulin, alpha 8
chr5_-_92982927 1.513


chr12_+_56284867 1.492 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr22_+_16973399 1.450 NM_001193414
NM_018943
TUBA8

tubulin, alpha 8

chr11_-_124311512 1.352 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr3_+_32834513 1.335 NM_001039111
TRIM71
tripartite motif containing 71
chr14_+_94117483 1.295 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr2_-_230494956 1.210 TRIP12
thyroid hormone receptor interactor 12
chr16_+_31027231 1.204 BCKDK
branched chain ketoacid dehydrogenase kinase
chr1_-_3806683 1.169 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr19_-_56582997 1.156 NM_001161748
NM_030657
LIM2

lens intrinsic membrane protein 2, 19kDa

chr2_+_74594093 1.145 TLX2
T-cell leukemia homeobox 2
chr17_+_18320822 1.123 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr2_-_230494862 1.104 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr17_-_8006979 1.084 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr11_-_65841077 1.075 NM_020404
CD248
CD248 molecule, endosialin
chr19_-_48700824 1.064 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr19_-_12456544 1.037 ZNF709
zinc finger protein 709
chr16_+_18986417 1.028 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr9_+_139245029 1.024 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr19_-_12305435 1.021 NM_145276
ZNF563
zinc finger protein 563
chr16_+_18986721 0.978 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr16_+_18986459 0.948 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr11_+_76516957 0.939 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr7_+_128365226 0.933 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr5_-_178984192 0.922 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr16_+_31027115 0.917 NM_001122957
NM_005881
BCKDK

branched chain ketoacid dehydrogenase kinase

chr20_+_3749164 0.911 NM_018347
C20orf29
chromosome 20 open reading frame 29
chr1_+_199259664 0.907


chr1_+_93830169 0.901 LOC100129046
hypothetical LOC100129046
chr11_-_124311106 0.858 HEPACAM
hepatic and glial cell adhesion molecule
chr19_-_1601246 0.853 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr17_-_61655915 0.849 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr10_-_43212166 0.848 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr19_+_12036513 0.841 NM_001136501
ZNF844
zinc finger protein 844
chr20_+_18516541 0.828 NM_080820
DTD1
D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
chr1_+_93830106 0.822 LOC100129046
hypothetical LOC100129046
chr16_-_88295595 0.819 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr2_+_222997456 0.818 SGPP2
sphingosine-1-phosphate phosphatase 2
chr1_-_20122638 0.812 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr22_+_48966480 0.792 NM_025204
TRABD
TraB domain containing
chr7_+_39956633 0.786 CDK13
cyclin-dependent kinase 13
chr10_-_21825879 0.778 C10orf114
chromosome 10 open reading frame 114
chr12_+_119900677 0.757 HNF1A
HNF1 homeobox A
chr17_-_20311411 0.756 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr3_-_27739201 0.746 EOMES
eomesodermin
chr5_-_32210084 0.738 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr7_+_39956480 0.736 NM_003718
NM_031267
CDK13

cyclin-dependent kinase 13

chr11_+_2378559 0.729 TSSC4
tumor suppressing subtransferable candidate 4
chr16_+_31027249 0.727 BCKDK
branched chain ketoacid dehydrogenase kinase
chr18_-_31178415 0.727 NM_006965
ZNF24
zinc finger protein 24
chr1_-_3806564 0.722 C1orf174
chromosome 1 open reading frame 174
chr19_-_14121728 0.719 LPHN1
latrophilin 1
chr19_+_10515570 0.714 ATG4D
ATG4 autophagy related 4 homolog D (S. cerevisiae)
chr18_-_31178379 0.700 ZNF24
zinc finger protein 24
chrX_+_46825179 0.685 RGN
regucalcin (senescence marker protein-30)
chr13_+_49658016 0.677


chr19_-_12456625 0.649 NM_152601
ZNF709
zinc finger protein 709
chr7_-_44547382 0.644 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr14_+_94117511 0.639 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr14_-_63076155 0.631 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr12_-_109611277 0.629 NM_032369
HVCN1
hydrogen voltage-gated channel 1
chr17_+_72958920 0.626 SEPT9
septin 9
chr5_-_32210142 0.615 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chrX_-_39921525 0.613 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr17_-_7023378 0.605 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr5_-_32210112 0.603 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr1_-_55103938 0.600 DHCR24
24-dehydrocholesterol reductase
chr11_+_7491789 0.592 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_-_32210154 0.591 NM_022130
GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr21_+_44699796 0.586 NM_030891
LRRC3
leucine rich repeat containing 3
chr10_-_101831579 0.582 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr3_+_185514937 0.581 NM_001194946
NM_001194947
NM_198241
NM_198242
NM_198244
EIF4G1




eukaryotic translation initiation factor 4 gamma, 1




chr16_+_31027255 0.580 BCKDK
branched chain ketoacid dehydrogenase kinase
chr8_-_93184629 0.578 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr2_+_20510312 0.576 NM_004040
RHOB
ras homolog gene family, member B
chr7_+_39956396 0.576


chr7_+_128365482 0.576 NM_032643
IRF5
interferon regulatory factor 5
chr2_+_128175413 0.573 SFT2D3
SFT2 domain containing 3
chr17_-_40843530 0.572 ARHGAP27
Rho GTPase activating protein 27
chr2_+_222997529 0.568 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr7_+_142788480 0.566 NM_001010972
NM_003461
ZYX

zyxin

chr16_+_1974182 0.562 GFER
growth factor, augmenter of liver regeneration
chr17_+_2646481 0.562 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr7_+_142788579 0.559 ZYX
zyxin
chr5_-_179166230 0.554 MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr8_-_8276598 0.546 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr19_-_47451119 0.540 NM_006494
ERF
Ets2 repressor factor
chr6_+_31538934 0.540 NM_006674
HCP5
HLA complex P5
chr11_-_780103 0.536 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr2_+_108271526 0.533 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chrX_-_130250715 0.532 NM_001170963
IGSF1
immunoglobulin superfamily, member 1
chr1_-_1840564 0.530 NM_178545
TMEM52
transmembrane protein 52
chr2_+_74595073 0.519 NM_016170
TLX2
T-cell leukemia homeobox 2
chr3_-_49117169 0.502 NM_005051
QARS
glutaminyl-tRNA synthetase
chr16_-_65742323 0.493 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr11_+_55884266 0.492 NM_001005205
OR8J1
olfactory receptor, family 8, subfamily J, member 1
chr17_-_31831093 0.487 NM_001123392
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
TBC1 domain family, member 3F
chr17_-_59451662 0.480 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr17_+_77528699 0.479 NM_024083
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr11_+_63883192 0.477 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr3_+_185515108 0.475 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr7_-_122126422 0.475 NM_139175
RNF133
ring finger protein 133
chr3_+_185515013 0.471 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_-_47450991 0.470 ERF
Ets2 repressor factor
chr16_+_30952350 0.470 STX4
syntaxin 4
chr21_-_45165249 0.446 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_-_36469869 0.442 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr19_+_50100843 0.441 NM_000041
APOE
apolipoprotein E
chr5_-_176868483 0.435 DOK3
docking protein 3
chr5_-_32209999 0.435 GOLPH3
golgi phosphoprotein 3 (coat-protein)
chr12_-_6668085 0.435 NM_001039916
ZNF384
zinc finger protein 384
chr16_+_30952382 0.432 NM_004604
STX4
syntaxin 4
chr17_+_62803824 0.432 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_1170045 0.430 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr11_+_72765318 0.428 NM_032871
RELT
RELT tumor necrosis factor receptor
chr4_-_2727548 0.425 NM_001161527
TNIP2
TNFAIP3 interacting protein 2
chr20_+_42463419 0.408 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_+_10652025 0.408


chr20_+_46971618 0.406 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr17_+_77528782 0.398 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr7_+_97679501 0.391 NM_177455
BHLHA15
basic helix-loop-helix family, member a15
chr8_-_23596346 0.389 NM_006167
NKX3-1
NK3 homeobox 1
chr17_+_35751796 0.381 NM_001024809
RARA
retinoic acid receptor, alpha
chr16_+_658081 0.379 NM_138769
RHOT2
ras homolog gene family, member T2
chr10_-_43212703 0.376 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr21_-_45165204 0.373 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_+_62804036 0.370 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_23623713 0.362 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr17_-_36456949 0.348 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr20_+_337346 0.347 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr17_-_6557375 0.347 NM_001143838
NM_177550
SLC13A5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr16_+_14634324 0.344 BFAR
bifunctional apoptosis regulator
chr3_-_13032130 0.343


chr10_+_30763056 0.340 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr17_+_77603064 0.337 GPS1
G protein pathway suppressor 1
chr9_-_135593265 0.332 NM_001134707
SARDH
sarcosine dehydrogenase
chr8_-_37576515 0.331 LOC157860
hypothetical protein LOC157860
chr17_+_77603028 0.328 NM_004127
NM_212492
GPS1

G protein pathway suppressor 1

chr19_-_63550712 0.317 A1BG
alpha-1-B glycoprotein
chr16_+_27320983 0.313 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr4_+_2764510 0.312 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr16_+_55950195 0.312 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr11_+_65164167 0.308 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr12_+_54700955 0.305 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr20_-_33658823 0.304 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr3_+_171558188 0.299 SKIL
SKI-like oncogene
chr5_-_180169720 0.298 NM_001114617
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chrX_-_109570113 0.295 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr5_+_133889584 0.294 NM_015288
PHF15
PHD finger protein 15
chr21_-_34908614 0.293 NM_203417
RCAN1
regulator of calcineurin 1
chr10_+_111757867 0.293 ADD3
adducin 3 (gamma)
chr17_+_75808685 0.286 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr3_+_171558143 0.281 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr17_+_69974375 0.279 CD300A
CD300a molecule
chr16_+_620932 0.278 NM_053284
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr4_-_2727816 0.275 NM_024309
TNIP2
TNFAIP3 interacting protein 2
chr16_+_11978002 0.273 NM_032167
RUNDC2A
RUN domain containing 2A
chr11_+_76561471 0.270 MYO7A
myosin VIIA
chr16_-_2710552 0.268 NM_031948
PRSS27
protease, serine 27
chr3_+_171558215 0.268 SKIL
SKI-like oncogene
chr12_-_56422120 0.264 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_+_23508922 0.264 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr6_+_3697328 0.261


chr11_-_63841556 0.258 NM_016404
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr11_-_780065 0.256 CEND1
cell cycle exit and neuronal differentiation 1
chr10_+_80569464 0.254 ZMIZ1
zinc finger, MIZ-type containing 1
chr17_-_31616071 0.254 NM_001001418
NM_032258
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chr8_+_38877909 0.253 NM_021623
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr12_+_52181643 0.253 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr14_+_49429474 0.248 NM_001663
ARF6
ADP-ribosylation factor 6
chr2_+_104837004 0.248


chr16_-_4232053 0.246 NM_001098814
SRL
sarcalumenin
chr15_-_87565813 0.246 NM_000326
RLBP1
retinaldehyde binding protein 1
chr16_-_3707450 0.245 NM_016292
TRAP1
TNF receptor-associated protein 1
chr17_+_4434024 0.243 NM_198501
SMTNL2
smoothelin-like 2
chr16_-_2201011 0.242 NM_182563
C16orf79
chromosome 16 open reading frame 79
chr20_+_39199263 0.242 PLCG1
phospholipase C, gamma 1
chr14_-_106352471 0.242


chr19_+_10515591 0.241 NM_032885
ATG4D
ATG4 autophagy related 4 homolog D (S. cerevisiae)
chr20_-_52223918 0.240 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr11_-_66945190 0.237 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr19_-_41090960 0.236 TYROBP
TYRO protein tyrosine kinase binding protein
chr19_+_40223249 0.235 NM_002151
NM_182983
HPN

hepsin

chr22_+_48740432 0.234 PIM3
pim-3 oncogene
chr11_-_116168316 0.233 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr16_+_76313909 0.230 NM_001105663
NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_2764609 0.229 SH3BP2
SH3-domain binding protein 2
chr2_-_217268492 0.226 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr14_-_22515725 0.225 JUB
jub, ajuba homolog (Xenopus laevis)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.